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MIRAGE
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Zfp36TTP:mRNA ComplexTnpo1mRNA Transcript Targeted by TristetraprolineTTP:mRNA Degradation ComplexXrn1Dcp1aDCP2Exosome ComplexPhosphorylated TTP:mRNA ComplexATPADPYwhabPhosphorylated TTP:mRNA:14-3-3 Complex
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P97789 5'-3' exoribonuclease 1
  • Dhm2
  • Exo
  • Sep1
  • Xrn1
 view
Q91YD3 mRNA-decapping enzyme 1A
  • Dcp1a
  • Mitc1
  • Smif
 view
Q9CSH3 Exosome complex exonuclease RRP44
  • Dis3
  • Kiaa1008
  • Rrp44
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025