RHO GTPases Activate WASPs and WAVEs

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Rac1-GTPWRC:IRSp53/58:RAC1:GTP:PIP3WAVE Regulatory ComplexPIP3Baiap2ATPp-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3ADPp-Y-WRC:IRSp53/58:RAC1:GTP:PIP3CDC42:GTP:WASP/N-WASP:WIP:SH3 proteinsCDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteinsWAVE2, WASP, N-WASP:ARP2/3 complex:G-actinMother filament:branching complexF-actinWAVE2, WASP, N-WASPMother filament:ARP2/3:actin:ADPG-actinMother filament:branching complex:daughter filament
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025