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MIRAGE
Fanconi Anemia Pathway

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Faap24FANCM:FAAP24FANCMFANCM:FAAP24:APITD1:STRA13:ICL-DNAFA Core Complex:ICL-DNAFAAP20FancgFanceFancbFancaFanclFancfA2ACJ2FanccFanciFANCD2:FANCIFancd2FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNAUbe2tATR:ATRIPFANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIPRPA heterotrimerp-FANCD2:p-FANCI:UBE2T:p-FA Core Complex:ICL-DNAATPp-RPA heterotrimerADPUbMonoUb:K91,K182-UBE2TMonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNAp-FA Core Complex:ICL-DNAp-FANCD2:p-FANCIFAN1MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleasesERCC1:ERCC4SLX1A:SLX4:MUS81:EME1,(MUS81:EME2)DCLRE1A,DCLRE1BMonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNAPolnMonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLNDNA double-strand break endsdNTPp-FA Core ComplexPPiDistorted dsDNAMonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025