Regulation of TP53 Activity through Methylation

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Ttc5Q99LG4ATPADPQ99LG4EP300p-S203,S221-TTC5:EP300:JMYJmyp-S15,S20-TP53 Tetramer:p-S203,S221-TTC5:EP300:JMYp-S15,S20-TP53 TetramerUbJmyPRMT5p-S15,S20-TP53 Tetramer:p-S203,S221-TTC5:EP300:JMY:PRMT5p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer:p-S203,S221-TTC5:EP300:JMY:PRMT5SAMSAHMe1-K370,p-S15,S20-TP53 TetramerMe-K382,p-S15,S20-TP53 TetramerA2A5N8L3MBTL1:Me-K382,p-S-15,S20-TP53Me2-K373-TP53 TetramerTP53 Tetramer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
B2RWS6 Histone acetyltransferase p300
  • Ep300
  • P300
view
P02340 Cellular tumor antigen p53
  • P53
  • Tp53
  • Trp53
view
P0CG49 Polyubiquitin-B
  • Ubb
view
Q5DW34 Histone-lysine N-methyltransferase EHMT1
  • Ehmt1
  • Euhmtase1
  • Glp
  • Kmt1d
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025