PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PIP2ADPATPPIP3PI5PP31750AKT1H2OPiPP2Ap-Y307-PP2Ap-ERK dimerPP2A-B56-beta,gamma:IER3:p-T,Y-MAPK dimersIer3p-S-B56-beta,gammaPP2A-A:PP2A-CPI4PPP2A-B56-beta,gamma
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025