Regulation of IFNG signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3SOCS-1 and SOCS-3Sumo1p-STAT1 dimer:PIAS:SUMO1p-STAT1 homodimerPias1H2OStat1Pi
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P01580 Interferon gamma
  • Ifng
view
P15261 Interferon gamma receptor 1
  • Ifngr
  • Ifngr1
view
P52332 Tyrosine-protein kinase JAK1
  • Jak1
view
Q06180 Tyrosine-protein phosphatase non-receptor type 2
  • Ptpn2
  • Ptpt
view
Q63953 Ifngr2 protein
  • Ifngr2
  • ifngr2
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025