E3 ubiquitin ligases ubiquitinate target proteins

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Ub:UBE2D1,2,3PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14UBE2D1,2,3PrkdcRNF144A:PRKDC:Ub:UBE2L3Q925F3Ub:UBE2L3PrkdcUbe2l3Rnf152RNF152:RRAGA:GDP:Ub:UBE2NRRAGA:GDPUb:UBE2NK63polyUb-K142,K220,K230,K244-RRAGA:GDPUbe2nRnf181RNF181:BCL10:Ub:E2Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2NBcl10Bcl10UBE2D1,UBE2D2,UBE2D3,UBE2E1,UBE2NHistone HIST1H2BPAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2BPAF1CUb:UBE2A,BWacRNF20:RNF40HIST1H2BA-D,H,J-OUBE2A,BUb:UBE2N:UBE2V2SHPRH:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2SHPRHRAD18:UBE2BMonoUb:K164-PCNA homotrimerUBE2N:UBE2V2K63polyUb-K164-PCNA homotrimerHLTF:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2HLTF
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 11 - 14 of 14 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q8CGP2 Histone H2B type 1-P
  • Hist1h2bp
view
Q8K2T8 RNA polymerase II-associated factor 1 homolog
  • Paf1
view
Q924H7 WW domain-containing adapter protein with coiled-coil
  • Kiaa1844
  • Wac
view
Q9D2M8 Ubiquitin-conjugating enzyme E2 variant 2
  • Mms2
  • Ube2v2
  • Uev2
view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025