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MIRAGE
LDL clearance

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
LDLLDL:LDLR complexLdlrLDL:LDLR complexLDL:LDLR complexLDLLdlrLDLH2OCHOLFALIPA-degraded LDLNPC2:CHOLNpc2NPC1NPC1:CHOLCHOLacyl-CoACHESTCoA-SHCHESTCHOLLCFA(-)H2OPcsk9PCSK9:LDLRPCSK9:PCSK9 inhibitorsPCSK9 inhibitorsPCSK9:LDLR:Clathrin:AP2Clathrin:AP-2 complexPCSK9:LDLR:Clathrin:AP2Clathrin:AP2 complex
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 11 - 15 of 15 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q8BLF1 Neutral cholesterol ester hydrolase 1
  • Aadacl1
  • Kiaa1363
  • Nceh1
 view
Q8VCU1 Carboxylesterase 3B
  • Ces3b
  • Gm4738
 view
Q9DBG3 AP-2 complex subunit beta
  • Ap2b1
  • Clapb1
 view
Q9Z0J0 NPC intracellular cholesterol transporter 2
  • Npc2
 view
Q9Z0M5 Lysosomal acid lipase/cholesteryl ester hydrolase
  • Lip1
  • Lipa
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025