Antigen processing: Ubiquitination & Proteasome degradation

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
UbE1 bound ubiquitinATPAMPMg2+Activating enzymes E1PPiE2 Ubiquitin-conjugating enzymeUbiquitin:E2 conjugating enzymesantigenic substrateAg-substrate:E3:E2:UbE3 ligases in proteasomal degradationE3:Ub:substrateE3:K48-polyubiquitinated substrateK48polyUb-antigenic substrateoligopeptideL-amino acidoligopeptideoligopeptide
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 2 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_000374 Q80UW2 F-box only protein 2 view
GL_001479 Q9QZN4 F-box only protein 6 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025