Antigen Presentation: Folding, assembly and peptide loading of class I MHC

Summary
Species
Mus musculus
Reactome
PubChem
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Chaperones calnexin/BiPmonoglucosylated MHC class I HC:Calnexin/BiPmonoglucosylated MHC class I HCB2mMHC HC:B2M:Erp57MHC class I HC:Calnexin/BiP:Erp57TapbpMHC:B2M peptide loading complexTAPBAP31 oligomerCALRATPPiH2OoligopeptideADPoligopeptideL-amino acidoligopeptideAntigenic peptide:MHC:B2M peptide loading complexErp57Antigen peptide bound class I MHC:BAP31 oligomerPeptide bound class I MHCSEC23:SEC24SAR1B:GTP:SEC23:SEC24SAR1B:GTPSec31aCOPII vesicle with MHC class ISar1p:GTP:Sec23p:Sec24p:Ag bound MHC class ISec13COPII vesicle with MHC class IAntigen peptide bound class I MHCGDPGTPSEC24SEC23ASAR1B:GDPAntigen peptide bound class I MHCAntigen peptide bound class I MHC
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025