Factors involved in megakaryocyte development and platelet production

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
RAD51CRAD51B:RAD51CRAD51BRAD51B:RAD51C:Single-stranded DNASingle-stranded DNAPKA tetramerDual-specific AKAPs:PKA tetramerDual-specific AKAPsMitofusinsMitofusin complexCbx5HP1alpha:Histone H3 methylated at K9Histone H3 methylated at lysine-9ATPI(1,3,4,5,6)P5ADPI(3,4,5,6)P4I(1,3,4)P3I(1,3,4,5)P4I(1,3,4,6)P4Q6EDY6LRRC16A:F-actin capping proteinCapza1,2:CapzbCapzbCapza1,2BHC complexBHC complex:REST:REST DNA binding sitesREST:REST DNA binding sitesZFPM1, ZFPM2ZFPM proteins:GATA proteinsGATA proteinsHistone H3 mono or di-methylated at K9Histone H3 mono- or unmethylated at K9Q62120SH2B family:p-Y813-JAK2SH2B familyGTPADPGDPAMPNF-E2NF-E2:Promoter region of beta-globinPromotor region of beta-globinC-terminal EH domain containing proteinsC-terminal EH domain containing proteins:Rabenosyn-5Q80Y56Rabenosyn-5:VPS-45Vps45RAB5ADOCK-GEFsDOCK-GEFs:RAC1, CDC42RAC1, CDC42
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025