Tie2 Signaling

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Angpt1ANGPT1:TEKTEK2xANGPT1:TEKANGPT1:p-5Y,S119-TEKp85 bound to Tie2PI3KGrb2 bound to Tie2Grb2Sos1SOS-1 bound to Tie2:Grb2p21 RAS:GDPGDPp21 RAS:GTPGTPShc1ANGPT1:p-5Y,S119-TEK:SHC1Dok2Tie2 and Dok-2 complexANGPT2ANGPT2:TEKANGPT4:TEKAngpt4pTie2 and SHP2 complexPTPN11Grb7Tie2:Grb7 complexTie2 and Grb14 complexGrb14
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 2 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O35460 Angiopoietin-1
  • Angpt1
view
O35462 Angiopoietin-2
  • Agpt2
  • Angpt2
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025