EPHB-mediated forward signaling

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PIP2p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTPARP2/3 complex (ATP bound)p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actinG-actinKALRNEFNBs:p-EPHBs:KALRNp-EPHB:EFNB oligomersGTPRAC1:GTPRAC1:GDPGDPPAK1 dimerRAC1:GTP:PAK1 dimer:RAC1:GTPRAC1-GTP:p-S144,T423-PAK1ATPADPEFNBs:p-EPHBs:p-Y397-PTK2EFNBs:p-EPHBs:p-Y397-PTK2:ARHGEF28P0C6P5RHOA:GTPGDPRHOA:GDPRHOA:GTP:ROCK1,ROCK2ROCK1,ROCK2Tiam1EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:GlyEFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:p-Y829-TIAM1RAC1:GDPRac1:GTPHRAS:GTPp-EPHBs:EFNBs:RASA1:HRAS:GTPp-EPHBs:EFNBs:RASA1H2Op-EPHBs:EFNBs:RASA1:HRAS:GDPPiP34900Sdc2p-Y179,Y191-SDC2 cluster
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P34900 Syndecan-2
  • Hspg1
  • Sdc2
  • Synd2
view
P35439 Glutamate receptor ionotropic, NMDA 1
  • Grin1
  • Nmdar1
view
P60711 Actin, cytoplasmic 1
  • Actb
view
Q00960 Glutamate receptor ionotropic, NMDA 2B
  • Grin2b
view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025