Vasopressin regulates renal water homeostasis via Aquaporins

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PKA tetramerPKA tetramer:4xcAMPcAMPcAMP:PKA regulatory subunitPRKACA,PRKACB,PRKACGAvpr2AVPR2:AVP(20-28)AvpGTPAVPR2:AVP:G-alpha(s):GTP:G-beta:G-gammaAVPR2:AVP:G-alpha(s):GDP:G-beta:G-gammaGDPAQP2 tetramerADPp-S256-AQP2 tetramerATPp-S256-AQP2 tetramerH2OH2O
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 6 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P01186 Vasopressin-neurophysin 2-copeptin
  • Avp
view
P29975 Aquaporin-1
  • Aqp1
  • Chip28
view
P34080 Aquaporin-2
  • Aqp2
view
P47862 Aquaporin-3
  • Aqp3
view
P47863 Aquaporin-4
  • Aqp4
view
Q00788 Vasopressin V2 receptor
  • Avpr2
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025