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MIRAGE
PINK1-PRKN Mediated Mitophagy

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PINK1PINK1B5DFG1PINK1ATPp-S228,S402-PINK1:p-S228,S402-PINK1ADPp-S65-Ub:MOM proteinsUb-MOM proteinsPRKNPRKN:Ub-MOM proteinsp-S65-PRKN:Ub-MOM proteinsK48polyUb-MOM proteinsK48polyUB Mitophagy Substrates:SQSTM1SQSTM1LC3:K48polyUB Mitophagy Substrates:SQSTM1LC3ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1ATG5:ATG12OPTNTBK1:OPTN:K63-polyUb-mitochondrial proteinsK63polyUb-MOM proteinsTbk1p-S172-TBK1:OPTN:K63polyUb-mitochondrial proteinsp-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteinsMAP1LC3B:p-S-TBK1:p-S-OPTN:K63polyUb-mitochondrial proteinsQ62625ATG9A:p-S172-TBK1:p-S177-OPTN:K63polyUb-mitochondrial proteinsAtg9a
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P81155 Non-selective voltage-gated ion channel VDAC2
  • Vdac2
 view
Q5FWU3 Autophagy-related protein 9A
  • Apg9l1
  • Atg9a
 view
Q9Z2L0 Non-selective voltage-gated ion channel VDAC1
  • VDAC
  • Vdac1
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025