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MIRAGE
TNFR1-induced NF-kappa-B signaling pathway

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TNF-α:TNFR1:TRADD:RIPK1:TRAF2TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3BIRC2,3,4K63polyUbTNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4TAK1 complexTNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBACCHUK:IKBKB:IKBKGTNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:CHUK:IKBKB:IKBKG
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
A0A8I6AL23 ubiquitinyl hydrolase 1
  • Tnfaip3
 view
P0C8E4 Mitogen-activated protein kinase kinase kinase 7
  • Map3k7
 view
P16599 Tumor necrosis factor
  • Tnf
  • Tnfa
  • Tnfsf2
 view
P22934 Tumor necrosis factor receptor superfamily member 1A
  • Tnfr-1
  • Tnfr1
  • Tnfrsf1a
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025