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MIRAGE
RHO GTPases Activate WASPs and WAVEs

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Baiap2WRC:IRSp53/58:RAC1:GTP:PIP3WAVE Regulatory ComplexPIP3Rac1:GTPCDC42:GTP:WASP/N-WASP:WIP:SH3 proteinsCDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteinsADPATPp-Y-WRC:IRSp53/58:RAC1:GTP:PIP3p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3F-actinMother filament:branching complexWAVE2, WASP, N-WASP:ARP2/3 complex:G-actinMother filament:ARP2/3:actin:ADPWAVE2, WASP, N-WASPMother filament:branching complex:daughter filamentG-actin
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
D4A8H8 Cytoplasmic FMR1-interacting protein
  • Cyfip1
 view
P60711 Actin, cytoplasmic 1
  • Actb
 view
Q5BJU7 Actin-binding protein WASF1
  • Wasf1
  • Wave1
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025