TNFR2 non-canonical NF-kB pathway

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TNF(1-233) trimerTNF-alpha inhibitors:TNF(1-233) trimerTNF-alpha inhibitorsTRAF2:cIAP1,2cIAP1,2:TRAF2:TRAF3:NIKTRAF3:NIKK48polyUbTraf3D3ZTD1Q80WY6TNFA trimer:TNFR2TNFA trimer:TNFR2 trimerTNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIKK63polyUbTNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIKNon-canonical NF-kB initiating TNFRSF memebersTNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIKD3ZTD1TNFRSF:TNFSF trimersTRAF1:TRAF2:K63polyUb-cIAP1,2
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025