TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
CD40 trimerCD40:CD40L trimerCD40LG trimerLTBR:lymphotoxin,TNFSF14 trimer3xLTBR:lymphotoxin,TNFSF14 trimerLtbrcIAP1,2:TRAF2:TRAF3:NIK3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIKCD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIKD4A2813xBAFFR:BAFF trimersBAFF trimer3xBAFFR:BAFF trimer:TRAF3:NIKF1M8Z6RANK:RANKL,sRANKL trimerRANKL,sRANKL trimer3xRANK:RANKL,sRANKL trimer3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIKG3V6F93xFN14:sTWEAK,TWEAK homotrimersTWEAK,TWEAK homotrimers3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q06332 Lymphotoxin-alpha
  • Lta
  • Tnfb
  • Tnfsf1
view
Q9ESE2 Tumor necrosis factor ligand superfamily member 11
  • Opgl
  • Rankl
  • Tnfsf11
  • Trance
view
Q9Z2V2 CD40 ligand
  • Cd40l
  • Cd40lg
  • Tnfsf5
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025