Antigen processing: Ubiquitination & Proteasome degradation

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Mg2+PPiAMPUbATPE1 bound ubiquitinActivating enzymes E1E2 Ubiquitin-conjugating enzymeUbiquitin:E2 conjugating enzymesE3 ligases in proteasomal degradationAg-substrate:E3:E2:Ubantigenic substrateE3:Ub:substrateE3:K48-polyubiquitinated substrateK48polyUb-antigenic substrateL-amino acidoligopeptideoligopeptideoligopeptide
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying 1 entry
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_001478 Q923V4 F-box only protein 6 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025