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MIRAGE
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells

Summary
Species
Saccharomyces cerevisiae
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATPQ12236ADPPDPK1PKN2P24583p-S473-AKT1:PIP3AKT1:PIP3p-T308,S473-AKT1:PIP3palmitoylated, myristoylated eNOS dimerp-S1177-eNOS dimerp-S1177,S1179-eNOS dimerPKA tetramerPKA tetramer:4xcAMPcAMPcAMP:PKA regulatory subunitPRKACA,PRKACB,PRKACGp-S633-eNOS dimer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying 1 entry
UniProt ID Protein Name Gene Symbol Pathway Viewer
P38346 Probable target of rapamycin complex 2 subunit BIT2
  • BIT2
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025