GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **251 - 275** of **557** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Lactose synthesis	Beta-1,4-galactosyltransferase 1 Solute carrier family 2, facilitated glucose transporter member 1	P08037 P27674	B4GALT1 GALT GGTB2 GLUT1 SLC2A1	Bos taurus (cattle)	G58161NS G74621DY
Interaction With Cumulus Cells And The Zona Pellucida	Beta-1,4-galactosyltransferase 1 Disintegrin and metalloproteinase domain-containing protein 2 Hyaluronidase Oviduct-specific glycoprotein Zona pellucida sperm-binding protein 2 Zona pellucida sperm-binding protein 3 Zona pellucida sperm-binding protein 4	A0A3Q1MHW1 A0A3S5ZPD7 A6H6X7 F1MZM9 G1K1H0 P08037 Q9BH11	ADAM2 B4GALT1 GALT GGTB2 LOC509761 OVGP1 ZP2 ZP3 ZP4 ZPB	Bos taurus (cattle)
Glycosphingolipid biosynthesis	Beta-1,4 N-acetylgalactosaminyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Ceramide kinase Gal-NAc6S Galactoside alpha-(1,2)-fucosyltransferase 1 Hexosyltransferase Hexosyltransferase L-Fucosyltransferase Lactosylceramide 4-alpha-galactosyltransferase Lactosylceramide alpha-2,3-sialyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 UDP glycosyltransferase 8 ceramide glucosyltransferase	A0A3Q1LUC6 A0A3Q1MPZ8 A0A452DJH9 A4IFB0 E1BCQ2 F1MUJ7 F1MUS1 F1MXN8 F1N2J4 F1N7G6 F6Q1T7 G3MXL8 G3MZ03 Q08DR4 Q2HJA3 Q58DI2 Q6H8M9	A4GALT B3GALT4 B3GNT5 B4GALNT1 B4GALT5 B4GALT6 CERK FUT1 FUT2 GALGT ST3GAL2 ST3GAL3 ST3GAL5 ST6GALNAC5 ST6GALNAC6 ST8SIA5 UGCG UGT8 siat4B	Bos taurus (cattle)
O-linked glycosylation of mucins	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase C1GALT1-specific chaperone 1 Glucosaminyl (N-acetyl) transferase 1 Glucosaminyl (N-acetyl) transferase 4 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Mucin 15, cell surface associated Mucin 20, cell surface associated Mucin-1 Mucin-2 Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase like 5 Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Sulfotransferase UDP-GlcNAc UDP-GlcNAc VWFD domain-containing protein	A0A3Q1LM69 A0A3Q1M2T0 A0A3Q1M633 A0A3Q1M6U9 A0A3Q1M986 A0A3Q1MN70 A0A3Q1MPZ8 A0A3Q1MQ00 A0A3Q1MUB2 A0A3Q1NK42 A0A3S5ZPG9 A6H6Z5 A6QLD9 A6QLX6 A7YY64 E1B9U7 E1BBP1 E1BCQ2 E1BDW8 E1BHN6 E1BKQ9 E1BPR6 F1MGN7 F1MSS4 F1MUJ7 F1MUW5 F6QA59 F6RJ62 G3N0Q1 G5E5A7 Q07537 Q08DM9 Q0VC83 Q0VC84 Q17QZ8 Q1LZD4 Q3SX46 Q7YQE1	B3GNT2 B3GNT4 B3GNT5 B3GNT6 B3GNT8 B3GNT9 B3GNTL1 B4GALT5 B4GALT6 C1GALT1 C1GALT1C1 CHST4 GALNT1 GALNT10 GALNT11 GALNT12 GALNT13 GALNT14 GALNT15 GALNT16 GALNT17 GALNT18 GALNT2 GALNT3 GALNT5 GALNT6 GALNT7 GALNT8 GALNTL1 GALNTL5 GCNT1 GCNT3 GCNT4 LOC789503 MUC1 MUC15 MUC2 MUC20	Bos taurus (cattle)
Basigin interactions	Basigin Caveolin-1 Integrin alpha-3 Integrin beta Integrin subunit alpha 6 Large neutral amino acids transporter small subunit 2 Monocarboxylate transporter 1 Myelin associated glycoprotein Peptidyl-prolyl cis-trans isomerase A RING-type E3 ubiquitin transferase SLC3A2 protein SLC7A10 protein SPN protein Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Solute carrier family 16 member 3 Solute carrier family 16 member 8 Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 9 Solute carrier family 7 member 11 Solute carrier family 7 member 5 Solute carrier family 7 member 7 Y+L amino acid transporter 2 interstitial collagenase	A0A140T8D2 A0A3Q1LVK3 A0A3Q1M8K4 A0A3Q1MGJ2 A0A3Q1N4D0 A0A3Q1NNN2 A6QLL5 A6QQF2 A6QQP5 F1MDA3 F1MMS9 F1MT97 F1MYX6 F6QYA3 F6RFP6 G3MWR4 G3N179 P62935 P79132 Q08DL0 Q2T9V1 Q3MHW6 Q3T0C6 Q3ZCL6	ATP1B1 ATP1B2 ATP1B3 BSG CAV1 ITGA3 ITGA6 ITGB1 LOC112441463 MAG PPIA PPIL2 SLC16A1 SLC16A3 SLC16A8 SLC3A2 SLC7A10 SLC7A11 SLC7A5 SLC7A6 SLC7A7 SLC7A8 SLC7A9 SPN	Bos taurus (cattle)
Integrin cell surface interactions	Basigin CD44 antigen Cadherin-1 Cartilage oligomeric matrix protein Collagen alpha-1(IV) chain Collagen type IV alpha 3 chain Collagen type XIII alpha 1 chain Collagen type XVI alpha 1 chain Collagen type XVIII alpha 1 chain Fibrillin-1 Fibronectin Integrin alpha-3 Integrin alpha-L Integrin beta-2 Integrin beta-6 Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 10 Integrin subunit alpha 11 Integrin subunit alpha 1 Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 4 Integrin subunit alpha 6 Integrin subunit alpha 9 Integrin subunit alpha M Integrin subunit alpha V Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 3 Intercellular adhesion molecule 5 Intercellular adhesion molecule N-terminal domain-containing protein JAM2 protein Junctional adhesion molecule A Leukocyte surface antigen CD47 Lumican Platelet and endothelial cell adhesion molecule 1 Purinergic receptor P2X 5 Secreted phosphoprotein 1 Tenascin C Thrombospondin 1 VCAM1 protein VWFA domain-containing protein Vitronectin	A0A140T8D2 A0A3Q1LT76 A0A3Q1LZT3 A0A3Q1LZU0 A0A3Q1M8K4 A0A3Q1MFX6 A0A3Q1MHJ9 A0A3Q1MQV3 A0A3Q1MSS6 A0A3Q1MXS2 A4IFI9 A7MBB0 E1BDD5 E1BFX5 E1BLR0 F1MBA3 F1MEF6 F1MGZ4 F1MI38 F1MMH2 F1MMN6 F1MMS9 F1MQF0 F1MQT9 F1MRZ6 F1MTN1 F1MVW3 F1MZU6 F1N157 F1N6W9 F6RFP6 F6RKH9 F6RND5 G3MXK9 G3MYD9 G5E5A9 P32592 P35445 P61625 P98133 Q05443 Q28862 Q3ZBS7 Q7SIB2 Q8SQB8 Q8SQB9 Q9XT56	BSG CD18 CD44 CD47 CDH1 COL13A1 COL16A1 COL18A1 COL4A1 COL4A3 COMP F11R FBN1 FN1 IBSP ICAM1 ICAM3 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA6 ITGA9 ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM1 JAM2 LDC LOC534578 LOC616254 LUM P2RX5 PECAM1 SPP1 THBS1 TNC VCAM1 VTN	Bos taurus (cattle)
Neurexins and neuroligins	Band 4.1-like protein 5 Calcium/calmodulin dependent serine protein kinase Carboxylesterase type B domain-containing protein DLG associated protein 1 DLG associated protein 3 DLG associated protein 4 Discs large MAGUK scaffold protein 3 Discs large MAGUK scaffold protein 4 Erythrocyte membrane protein band 4.1 like 1 Erythrocyte membrane protein band 4.1 like 2 Erythrocyte membrane protein band 4.1 like 3 Glutamate metabotropic receptor 1 Glutamate metabotropic receptor 5 Homer protein homolog 1 Homer scaffold protein 2 Homer scaffold protein 3 LRRTM2 protein LRRTM3 protein Leucine rich repeat transmembrane neuronal 4 Leucine-rich repeat transmembrane neuronal protein 1 Neurexin 3 Neuroligin 1 Neuroligin 2 Neuroligin 3 Protein 4.1 SH3 and multiple ankyrin repeat domains 1 SH3 and multiple ankyrin repeat domains 3 Sorbin and SH3 domain containing 2 Uncharacterized protein	A0A3Q1LHC4 A0A3Q1LPV4 A0A3Q1LRW9 A0A3Q1LWK1 A0A3Q1MBH0 A0A3Q1MUK3 A0A3Q1MV08 A1A4H9 A6H701 A6QNR7 E1B7S3 E1BBJ2 F1MDE0 F1MEA4 F1MM66 F1MW19 F1N104 F1N119 F1N5I2 F1N611 F6Q4B1 G3MXP5 G3N1H2 G3X7B4 G3X7N7 G5E618 Q2KJ56 Q58CU2 Q9N179	CASK DLG3 DLG4 DLGAP1 DLGAP3 DLGAP4 E41P EPB41 EPB41L1 EPB41L2 EPB41L3 EPB41L5 GRM1 GRM5 HOMER1 HOMER2 HOMER3 LRRTM1 LRRTM2 LRRTM3 LRRTM4 NLGN1 NLGN2 NLGN3 NLGN4X NRXN3 SHANK1 SHANK3 SORBS2	Bos taurus (cattle)
Antimicrobial peptides	BPI fold containing family A, member 2A BPI fold containing family B member 1 BPI fold containing family B member 2 BPI fold containing family B member 4 BPI fold containing family B member 6 BPI fold-containing family A member 1 Bactericidal permeability-increasing protein Cathelicidin-4 Clusterin Elastase, neutrophil expressed Fibrinogen C-terminal domain-containing protein Lactotransferrin Lipid-binding serum glycoprotein N-terminal domain-containing protein Lithostathine Liver-expressed antimicrobial peptide 2 Lysozyme C-1 Lysozyme C-2 Lysozyme C-3 Peptidase S1 domain-containing protein Peptidase inhibitor 3, skin-derived (SKALP) Peptidoglycan recognition protein 1 Peptidoglycan recognition protein 2 Peptidoglycan recognition protein 3 Peptidoglycan recognition protein 4 Phospholipase A2, membrane associated Proteinase 3 Rho guanine nucleotide exchange factor 40 Ribonuclease A family member 2 Ribonuclease A-domain domain-containing protein Ribonuclease K6 Saposin B-type domain-containing protein trypsin	A0A3Q1LIW8 A0A3Q1LWA5 A0A3Q1M1U5 A0A3Q1MPE3 A0A3Q1N0V6 A1A4Q6 A7YWU9 E1BAD2 E1BH94 F1MHQ2 F1MI67 F1MJS1 F1MLW2 F1MQW0 F6RMF1 G3MWP1 G3MXK8 G3MZA1 G3N3R4 P08904 P17453 P17697 P23132 P24627 P33046 Q06283 Q06284 Q06285 Q56JZ2 Q8SPP7 Q8SPU5 Q95JC3	ARHGEF40 BPI BPIFA1 BPIFA2A BPIFB1 BPIFB2 BPIFB4 BPIFB6 CATHL4 CLU ELANE LEAP2 LOC104968634 LOC112441508 LOC509956 LOC783267 LTF LYZ1 LYZ2 LYZ3 PGLYRP PGLYRP1 PGLYRP2 PGLYRP3 PGLYRP4 PGRP PI3 PLA2G2A PLUNC PRSS2 PRTN3 PTP RK6B RNASE2 RNASE6 RNS6	Bos taurus (cattle)	G49108TO
Translocation of ZAP-70 to Immunological synapse	BOLA-DQA1 protein BoLA-DR-alpha Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II antigen MHC class II antigen Major histocompatibility complex, class II, DQ alpha 5 Major histocompatibility complex, class II, DY alpha T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TRAV29-1*01 Tyrosine-protein kinase Tyrosine-protein kinase protein-tyrosine-phosphatase	A0A3Q1M088 A0A3Q1M3D2 A0A3Q1MT21 A6H6Y1 A6QQE7 E1BLZ1 E1BMP9 F1MJK4 F1MJU5 F1ML60 F1N0X9 F1N6L3 G3MWT2 G8JL01 Q0VCU4 Q28072 Q28073 Q30309 Q3ZCM0 Q70IB5	BLA-DQB BOLA-DQA1 BOLA-DQA2 BOLA-DQA5 BOLA-DRA BOLA-DRB2 BOLA-DRB3 BOLA-DYA BOLA-DYB BoLA-DIB BoLA-DRA BoLA-DYB CD247 CD3D CD3E CD3G CD4 DYB HLA-DRA LCK LOC100848815 PTPN22 TRAV29-1 ZAP70	Bos taurus (cattle)
PD-1 signaling	BOLA-DQA1 protein BoLA-DR-alpha Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II antigen MHC class II antigen Major histocompatibility complex, class II, DQ alpha 5 Major histocompatibility complex, class II, DY alpha Programmed cell death 1 ligand 2 Programmed cell death-ligand 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TRAV29-1*01 Tyrosine-protein kinase CSK Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type	A0A3Q1M088 A0A3Q1M2W6 A0A3Q1M3D2 A0A3Q1M739 A0A3Q1MT21 A6H6Y1 A6QQE7 C5NU11 E1BLZ1 F1MJK4 F1MJU5 F1ML60 F1N0X9 F1N339 G3MWT2 G8JL01 Q0VBZ0 Q0VCU4 Q28072 Q28073 Q30309 Q3ZCM0 Q70IB5	BLA-DQB BOLA-DQA1 BOLA-DQA2 BOLA-DQA5 BOLA-DRA BOLA-DRB2 BOLA-DRB3 BOLA-DYA BOLA-DYB BoLA-DIB BoLA-DRA BoLA-DYB CD247 CD274 CD3D CD3E CD3G CD4 CSK DYB HLA-DRA LCK LOC100848815 PD-L1 PDCD1LG2 PTPN11 PTPN6 TRAV29-1	Bos taurus (cattle)
Phosphorylation of CD3 and TCR zeta chains	BOLA-DQA1 protein BoLA-DR-alpha Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II antigen MHC class II antigen Major histocompatibility complex, class II, DQ alpha 5 Major histocompatibility complex, class II, DY alpha Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TRAV29-1*01 Tyrosine-protein kinase CSK Tyrosine-protein kinase peptidylprolyl isomerase protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A3Q1M088 A0A3Q1M3D2 A0A3Q1M6K1 A0A3Q1MT21 A6H6Y1 A6QQE7 E1BLZ1 F1MJK4 F1MJS9 F1MJU5 F1ML60 F1MQC1 F1N0X9 F1N6L3 G3MWT2 G8JL01 Q0VBZ0 Q0VCU4 Q28072 Q28073 Q30309 Q3ZCM0 Q70IB5	BLA-DQB BOLA-DQA1 BOLA-DQA2 BOLA-DQA5 BOLA-DRA BOLA-DRB2 BOLA-DRB3 BOLA-DYA BOLA-DYB BoLA-DIB BoLA-DRA BoLA-DYB CD247 CD3D CD3E CD3G CD4 CSK DYB HLA-DRA LCK LOC100848815 PAG1 PTPN22 PTPRC PTPRJ TRAV29-1	Bos taurus (cattle)
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-B Polyubiquitin-C Serine-threonine kinase receptor-associated protein Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta-1 proprotein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase	A0A3Q1LHW5 A0A3Q1LJ39 A0A3Q1N449 E1B7G3 E1B8T7 E1BE92 F1MUZ3 G3MZV8 O46680 P0CG53 P0CH28 P62992 P63048 Q1RMX1 Q5E959	BAMBI MTMR4 RPS27A SMAD2 SMAD3 SMAD7 SMURF2 STRAP STUB1 TGFB1 TGFBR1 TGFBR2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
Myogenesis	BCL2 interacting protein 2 BOC cell adhesion associated, onco regulated Cadherin 15 Cadherin-2 Cadherin-4 Catenin alpha 1 Catenin beta-1 Cell adhesion associated, onco regulated Cell division control protein 42 homolog Mitogen-activated protein kinase 11 Myocyte enhancer factor 2B Myocyte-specific enhancer factor 2C Myogenic factor 5 Myogenic factor 6 Myogenic factor Myogenin Sperm associated antigen 9 Transcription factor 12 Transcription factor 4 Transcription factor E2-alpha Tyrosine-protein kinase mitogen-activated protein kinase	A0A3Q1LI98 A0A3Q1LLQ6 A0A3Q1LQN2 A0A3Q1LTT9 A0A3Q1M9M0 A0A3Q1MB78 A0A3Q1NAH5 A0A3Q1NJ00 A0A5H1ZRH6 E1BB93 E1BHG3 F1MV33 F1MW29 F2Z4G1 G3X793 P17667 Q0VBX9 Q0VCX4 Q2KIA0 Q2KJ93 Q7YS80 Q7YS81	ABL1 BNIP2 BOC CDC42 CDH15 CDH2 CDH4 CDON CTNNA1 CTNNB1 MAPK11 MAPK14 MEF2B MEF2C MRF4 MYF5 MYF6 MYOD1 MYOG SPAG9 TCF12 TCF3 TCF4	Bos taurus (cattle)
Apoptotic execution phase	B-cell receptor-associated protein Caspase 8 Dynamin-1-like protein non-specific serine/threonine protein kinase	A2VE07 Q2KIA5 Q2LGB8 Q5E9F1	BCAP31 CASP8 DNM1L STK24	Bos taurus (cattle)
CD22 mediated BCR regulation	B-cell antigen receptor complex-associated protein alpha chain B-cell receptor CD22 CD79b molecule Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A3Q1LKV0 A0A3Q1M739 A0A3Q1NI55 F1MMQ7 F1N261 G5E513 P40293	CD22 CD79A CD79B IGA LYN MB-1 PTPN6	Bos taurus (cattle)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	B-cell activating factor Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing 3 CD40 ligand CD40 ligand LTBR protein Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 TNF receptor superfamily member 11a TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 12 TNF superfamily member 14 Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 5	A0A3Q1LHY0 A0A3Q1MKD6 A0A452DIT3 A6QQ46 B0LKN7 E1B9D9 E1BBH2 E1BIP0 E1BK50 E1BL08 F1MJD0 F1MTC1 F1MX43 F1N0K4 G3X822 Q06600 Q28203 Q3SYW8	BIRC2 BIRC3 CD40 CD40LG LTA LTB LTBR MAP3K14 NCR3 TNFB TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF5 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNLG1D TNLG7A TRAF2 TRAF3	Bos taurus (cattle)
TCF dependent signaling in response to WNT	Axin 2 Axin-1 Catenin beta-1 E3 ubiquitin-protein ligase RNF146-B Poly [ADP-ribose] polymerase Poly [ADP-ribose] polymerase Polyubiquitin-B Polyubiquitin-C Protein Wnt Protein Wnt Protein Wnt Protein Wnt Ubiquitin specific peptidase 34 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LTW2 A0A3Q1M230 A0A3Q1MDV7 E1B8R5 E1BDG5 E1BEN9 F1N5R1 G3X7P3 M5FK80 P0CG53 P0CH28 P62992 P63048 Q0VCX4 Q3T139	AXIN1 AXIN2 CTNNB1 RNF146B RPS27A TNKS TNKS2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP34 WNT1 WNT3 WNT3A WNT5A	Bos taurus (cattle)
Receptor Mediated Mitophagy	Autophagy protein 5 Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta FUN14 domain-containing protein 1 Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Serine/threonine-protein phosphatase PGAM5, mitochondrial Tyrosine-protein kinase Ubiquitin-like protein ATG12 Unc-51 like autophagy activating kinase 1	E1BIE7 E1BIM8 F1MFB2 F1MJ55 F1MZE2 F1N5S9 O41515 P67868 P68399 Q2HJ23 Q3MQ24	ATG12 ATG5 CK2A1 CK2N CSNK2A1 CSNK2A2 CSNK2B FUNDC1 MAP1ALC3 MAP1LC3 MAP1LC3A MAP1LC3B PGAM5 SRC ULK1	Bos taurus (cattle)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Autocrine motility factor receptor Derlin-1 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Polyubiquitin-B Polyubiquitin-C Transitional endoplasmic reticulum ATPase UBX domain-containing protein 1 UV excision repair protein RAD23 homolog B Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	A0A3Q1LKK4 E1BE05 E1BKB2 G3X757 P0CG53 P0CH28 P62992 P63048 Q29RK4 Q32KW2 Q71SS4	AMFR DERL1 ENGASE NGLY1 RAD23B RPS27A SAKS1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBXN1 VCP	Bos taurus (cattle)	G03934XO G25577BM G28233ME G51034LA G86419OL
Chemokine receptors bind chemokines	Atypical chemokine receptor 2 Atypical chemokine receptor 3 Atypical chemokine receptor 4 C motif chemokine ligand 1 C-C chemokine receptor type 5 C-C motif chemokine 20 C-C motif chemokine 2 C-C motif chemokine 4 C-C motif chemokine 5 C-C motif chemokine ligand 1 C-C motif chemokine ligand 21 C-C motif chemokine ligand 27 C-C motif chemokine receptor 10 C-C motif chemokine receptor 3 C-C motif chemokine receptor 4 C-C motif chemokine receptor 6 C-C motif chemokine receptor 8 C-C motif chemokine C-C motif chemokine C-C motif chemokine C-C motif chemokine C-C motif chemokine C-C motif chemokine C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 3 C-X-C chemokine receptor type 4 C-X-C chemokine receptor type 6 C-X-C motif chemokine 10 C-X-C motif chemokine 11 C-X-C motif chemokine 16 C-X-C motif chemokine 6 C-X-C motif chemokine 9 C-X-C motif chemokine receptor 5 C-X-C motif chemokine C-X-C motif chemokine C-X-C motif chemokine CCL25 protein CCR9 protein CX3C chemokine receptor 1 Chemokine (C-C motif) receptor 1 Chemokine C-C motif receptor-like 2 Chemokine interleukin-8-like domain-containing protein Eotaxin Growth-regulated protein homolog beta Growth-regulated protein homolog gamma Interleukin-8 Stromal cell-derived factor 1 X-C motif chemokine receptor 1	A0A3Q1LTZ4 A0A3Q1M085 A0A3Q1MHN9 A0A3Q1NB11 A0JN72 A4IF77 A4IF92 A5PKF1 A6QLA5 A6QNL7 A6YT15 A9QWP9 A9QWQ1 D9ZDE4 E1BAG6 E1BGB8 E1BH62 F1MD23 F1MD83 F1MP16 F1MT56 F1MYS4 F1MZ86 F1N2D2 F1N4S8 F6RDR3 G3N3U0 G5E6Q0 O46675 O46677 O97919 P25930 P28291 P35350 P79255 P80221 Q0II78 Q17QA1 Q1RMQ0 Q29RT9 Q2HJ17 Q2KIQ8 Q3ZBN3 Q56JW7 Q5EA94 Q5MD61 Q8SQB1 Q9BDJ2 Q9TTS6	ACKR2 ACKR3 ACKR4 CCL1 CCL11 CCL19 CCL2 CCL20 CCL21 CCL22 CCL25 CCL27 CCL28 CCL4 CCL5 CCR1 CCR10 CCR11 CCR3 CCR4 CCR5 CCR6 CCR8 CCR9 CCRL1 CCRL2 CMKBR5 CX3CR1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL16 CXCL3 CXCL6 CXCL8 CXCL9 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 GCP2 IL8 LOC100297044 LOC525415 LOC616364 MIP3A PPBP SCY4A SCYA2 SCYA20 SCYA5 SCYB6 XCL1 XCL2 XCR1	Bos taurus (cattle)
Physiological factors	Atrial natriuretic peptide receptor 2 C-type natriuretic peptide Carboxylic ester hydrolase Corin, serine peptidase Guanylate cyclase Natriuretic peptides A Neprilysin	A0A3Q1LLW8 A0A3Q1MQJ1 E1BN71 E1BPL8 P07501 P46197 P55206	CES1 CORIN MME NPPA NPPC NPR1 NPR2	Bos taurus (cattle)
RAF-independent MAPK1/3 activation	Astrocytic phosphoprotein PEA-15 Dual specificity protein phosphatase 10 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase protein-serine/threonine phosphatase protein-serine/threonine phosphatase	A0A3Q1MLC5 A6QLS1 E1B8P9 E1BAA9 F1MEZ2 F1MI99 F1MM08 F1MQM7 P46196 Q0IID7 Q0VCY8 Q2KJ36	DUSP1 DUSP10 DUSP16 DUSP4 DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 ERK2 MAPK1 MAPK3 PEA15 PRKM1	Bos taurus (cattle)
Glutamate and glutamine metabolism	Aspartate aminotransferase, mitochondrial Beta-citrylglutamate synthase B Delta-1-pyrroline-5-carboxylate synthase Glutamate dehydrogenase 1, mitochondrial Glutamine synthetase N-acetylaspartylglutamate synthase Ornithine aminotransferase Pyrroline-5-carboxylate reductase 1, mitochondrial Pyrroline-5-carboxylate reductase 2 Pyrroline-5-carboxylate reductase 3 glutaminase glutaminase	A0A140T871 E1BHZ6 F1MM79 F1MYG0 F1N0M1 P12344 P15103 Q0VCE9 Q17QJ7 Q2KJH7 Q58D08 Q58DT4	ALDH18A1 FAM80B GLS GLS2 GLUD1 GLUL GOT2 OAT PYCR1 PYCR2 PYCR3 PYCRL RIMKLA RIMKLB	Bos taurus (cattle)
Malate-aspartate shuttle	Aspartate aminotransferase, cytoplasmic Aspartate aminotransferase, mitochondrial Malate dehydrogenase, cytoplasmic Malate dehydrogenase, mitochondrial Mitochondrial 2-oxoglutarate/malate carrier protein Mitochondrial glutamate carrier 1 Solute carrier family 25 member 12	A0A3Q1M9V5 P12344 P22292 P33097 Q08DK4 Q32LG3 Q3T145	GC1 GOT1 GOT2 MDH1 MDH2 SLC20A4 SLC25A11 SLC25A12 SLC25A22	Bos taurus (cattle)
Asparagine N-linked glycosylation	Asialoglycoprotein receptor 1 Asialoglycoprotein receptor 2 Beta-1,4-N-acetyl-galactosaminyltransferase 2 Uromodulin	A0A3Q1LMR0 F1ME82 F1MWE7 Q32KM0	ASGR1 ASGR2 B4GALNT2 UMOD	Bos taurus (cattle)

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