GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **276 - 300** of **557** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism
Interleukin-12 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 12 receptor subunit beta 2 Interleukin-12 subunit alpha Interleukin-12 subunit beta Protein disulfide-isomerase Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A3Q1LXM0 E1BCP6 F1MCX4 F1MEB5 F1N0D6 F1N0R2 F6Q9Q9 G3MX29 P54349	IL12A IL12B IL12RB1 IL12RB2 JAK1 JAK2 P4HB STAT4 TYK2	Bos taurus (cattle)
EPH-Ephrin signaling	EFNA2 protein EFNA4 protein EPH receptor A10 EPH receptor B6 EPH-related receptor tyrosine kinase ligand 7 Ephrin A3 Ephrin B2 Ephrin B3 Ephrin type-B receptor 3 Ephrin-A1 Ephrin-B1 receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A3Q1LXH4 A0A3Q1MAA9 A0A3Q1MJW2 A1L570 A5D7J8 A6QLY0 E1BER5 E1BIE4 E1BJ31 E1BJS9 F1MII5 F1ML02 F1N0M5 F1N163 F1N3R6 F1N5D4 F1N6H6 F1N780 Q17R05 Q3ZC64	EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3 EPHA1 EPHA10 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6	Bos taurus (cattle)
PKMTs methylate histone lysines	ASH1 like histone lysine methyltransferase ASH2 like, histone lysine methyltransferase complex subunit Activating transcription factor 7 interacting protein Euchromatic histone lysine methyltransferase 1 Histone H3.1 Histone H3.2 Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Histone-lysine N-methyltransferase SETD7 Histone-lysine N-methyltransferase SETDB2 Histone-lysine N-methyltransferase, H3 lysine-79 specific Histone-lysine N-methyltransferase Histone-lysine N-methyltransferase Histone-lysine N-methyltransferase N-lysine methyltransferase KMT5A N-lysine methyltransferase SMYD2 NF-kappaB transcription factor p65 subunit NFKB2 protein Nuclear factor NF-kappa-B p105 subunit Nuclear receptor binding SET domain protein 1 Nuclear receptor binding SET domain protein 2 Nuclear receptor binding SET domain protein 3 PR/SET domain 16 PR/SET domain 9 PR/SET domain 9 Polycomb protein EED RBBP5 protein SET domain bifurcated histone lysine methyltransferase 1 SET domain containing 1A, histone lysine methyltransferase SET domain containing 1B, histone lysine methyltransferase SET domain containing 6, protein lysine methyltransferase SUZ12 polycomb repressive complex 2 subunit WD repeat domain 5 Zinc finger protein AEBP2 [histone H3]-lysine(4) N-methyltransferase [histone H3]-lysine(4) N-methyltransferase [histone H3]-lysine(4) N-trimethyltransferase [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B protein-histidine N-methyltransferase	A0A3Q1LX03 A0A3Q1M6A7 A0A3Q1M792 A0A3Q1M7L9 A0A3Q1MID6 A0A3Q1MJ82 A0A3Q1MSK4 A0A452DJ38 A1XG22 A4FUE3 A4FV57 A7MBB7 E1BEP4 E1BGA4 E1BKH5 E1BKN0 E1BLX2 E1BM66 E1BNH7 F1MHA1 F1MKW9 F1MMY4 F1MTF1 F1MUT0 F1MXG0 F1MYZ3 F1N093 F1N6Y5 F6R2J7 G3N3E5 G3X6G5 G3X6T4 G3X834 P62803 P68432 P84227 Q0P585 Q0P5C5 Q2YDJ8 Q3MHL3 Q3SWX8 Q3SZ25	AEBP2 ASH1L ASH2L ATF7IP DOT1L EED EHMT1 EZH2 KMT2A KMT2B KMT2C KMT5A KMT5B KMT5C NFKB1 NFKB2 NSD1 NSD2 NSD3 PRDM16 PRDM7 RBBP4 RBBP5 RBBP7 RELA SETD1A SETD1B SETD3 SETD6 SETD7 SETD8 SETDB1 SETDB2 SMYD2 SMYD3 SUV39H1 SUV39H2 SUZ12 WDR5	Bos taurus (cattle)
Acyl chain remodelling of PS	Cytosolic phospholipase A2 LPCAT4 protein Lysophospholipid acyltransferase 5 Membrane bound O-acyltransferase domain containing 1 Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein PLA2G12A protein Phospholipase A2, group XVI Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Secretory phospholipase A2 receptor	A0A3Q1LWY5 A0A3Q1LYR5 A0A3Q1MI45 A0A3Q1MNU5 A0A3Q1NMD6 A0JNE8 A4IFJ5 A5D7L0 E1BGU4 E1BNI4 F1MFD9 F1MG30 F1MNU5 F1MSG5 G8JL05 P00593 P49259 Q56JZ2	CPLA2 LOC613966 LPCAT3 LPCAT4 MBOAT1 OSBPL10 OSBPL5 OSBPL8 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G4 PLA2G4A PLA2G4D PLA2G4E PLA2G4F PLA2R1	Bos taurus (cattle)
Passive transport by Aquaporins	Aquaporin 10 Aquaporin 5 Aquaporin 7 Aquaporin 8 Aquaporin 9 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin Aquaporin Lens fiber major intrinsic protein	A0A3Q1LWN9 A0A3S5ZPM1 E1BDW5 F1MNJ1 F1N1C3 F1N3R5 F1N7X5 O77750 P06624 P47865 P79099 Q08DE6	AQP1 AQP10 AQP11 AQP12 AQP2 AQP3 AQP4 AQP5 AQP6 AQP7 AQP8 AQP9 MIP	Bos taurus (cattle)
Reversible hydration of carbon dioxide	Carbonic anhydrase 14 Carbonic anhydrase 1 Carbonic anhydrase 3 Carbonic anhydrase 4 Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase	A0A3Q1LWK4 A0A3Q1MI50 E1BPA4 F1MBS0 F1MIP9 F1MPL2 F1N0H3 F1N5D1 Q1LZA1 Q3SZX4 Q95323	CA1 CA12 CA13 CA14 CA2 CA3 CA4 CA5A CA5B CA6 CA9	Bos taurus (cattle)
LDL clearance	AP-1 complex subunit beta-1 AP-2 complex subunit alpha-2 AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma Apolipoprotein B Carboxylic ester hydrolase Clathrin heavy chain 1 Clathrin light chain A LDLRAP1 protein Low-density lipoprotein receptor NPC intracellular cholesterol transporter 2 Neutral cholesterol ester hydrolase 1 O-acyltransferase O-acyltransferase	A0A3Q1LVF9 A4IFV0 E1BNR0 F1MI11 F1N277 P01131 P04973 P49951 P79345 Q08DS7 Q0VCK5 Q17QC5 Q1JQE6 Q3T0N9 Q3ZC13	AADACL1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB CES3 CLTA CLTC LDLR LDLRAP1 NCEH1 NPC2 SOAT1 SOAT2	Bos taurus (cattle)
PI Metabolism	TNF alpha induced protein 8 like 3 Tumor necrosis factor alpha-induced protein 8-like protein 1 Tumor necrosis factor alpha-induced protein 8-like protein 2 Tumor necrosis factor alpha-induced protein 8	A0A3Q1LVF0 A4IF78 A5PK29 Q3ZBK5	TNFAIP8 TNFAIP8L1 TNFAIP8L2 TNFAIP8L3	Bos taurus (cattle)
Ion homeostasis	ATP binding cassette subfamily C member 9 ATP-sensitive inward rectifier potassium channel 11 Aspartyl/asparaginyl beta-hydroxylase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin-like Cardiac phospholamban Chloride intracellular channel 2 EF-hand domain-containing protein FXYD domain-containing ion transport regulator 6 FXYD domain-containing ion transport regulator 7 FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Nitric oxide synthase Peptidyl-prolyl cis-trans isomerase FKBP1B Phospholemman Plasma membrane calcium-transporting ATPase 4 Ryanodine receptor 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Short transient receptor potential channel 1 Sodium/calcium exchanger 1 Sodium/potassium-transporting ATPase subunit alpha-1 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Solute carrier family 8 member A2 Sorcin Stromal interaction molecule 1 cAMP-dependent protein kinase catalytic subunit alpha calcium/calmodulin-dependent protein kinase	A0A3Q1LV78 A0A3Q1LWV7 A0A3Q1M6M2 A0A3Q1M9U0 A0A3Q1MFU0 A0A3Q1MGH8 A0A3Q1MKC7 A0A3Q1MR28 A0A3Q1N7P8 A0A3Q1ND98 A0A3S5ZPA3 A2VDL6 A2VDS4 A2VE46 A6QLL5 D3K0R6 E1B7D0 E1B8N5 E1BHV1 E1BKE7 E1BMQ6 F1MC36 F1MLH6 F1MN60 F1MR06 F1MS16 F1MX21 F2Z4I4 F6QQY9 G3MWR4 P00517 P68107 Q08DA1 Q0VCY0 Q28056 Q2HJF7 Q3MHJ9 Q3MHZ5 Q3SZX0 Q3T0C6 Q3ZBJ3	ABCC9 ASPH ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 CALM CAMK2A CAMK2B CAMK2D CLIC2 FKBP12.6 FKBP1B FXYD1 FXYD2 FXYD4 FXYD6 FXYD7 ITPR1 ITPR2 ITPR3 KCNJ11 NOS1 PLM PLN PRKACA RYR2 SLC8A1 SLC8A2 SRI STIM1 TRPC1	Bos taurus (cattle)
Formation of the cornified envelope	Caspase 14 Corneodesmosin DSC1 protein Desmocollin 2 Desmocollin 3 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoplakin Envoplakin Junction plakoglobin Kallikrein C Kallikrein related peptidase 12 Kallikrein related peptidase 13 Kallikrein related peptidase 14 Kallikrein related peptidase 8 Lipase family member J Lipase Lipase Lipase Peptidase inhibitor 3, skin-derived (SKALP) Periplakin Plakophilin 1 Plakophilin 4 Protein-glutamine gamma-glutamyltransferase K Repetin Serine peptidase inhibitor Kazal type 5 Serine peptidase inhibitor Kazal type 9 Serine protease inhibitor Kazal-type 6 Trichohyalin pancreatic elastase II	A0A3Q1LV63 A0A3Q1LZM5 A0A3Q1M4I0 A0A3Q1NK79 A1A4Q6 A6QR67 E1B9D7 E1B9N6 E1BA50 E1BE09 E1BGD9 E1BKC5 E1BKT9 E1BM91 E1BNT1 F1MBB7 F1MFC2 F1MGR5 F1MIW8 F1MJ11 F1MJH0 F1MSA3 F1MWJ0 F1MXJ3 F1MXS5 F1MZF2 F1N2K8 G3MVZ9 G3N156 G3X7H1 P01001 Q8SPJ1	CASP14 CDSN CELA2A DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSG4 DSP EVPL JUP KLK12 KLK13 KLK14 KLK5 KLK8 KLNC LIPJ LIPK LIPM LIPN PI3 PKP1 PKP4 PPL RPTN SPINK5 SPINK6 SPINK9 TCHH TGM1	Bos taurus (cattle)
Phase 1 - inactivation of fast Na+ channels	Kv channel-interacting protein 4 Potassium voltage-gated channel interacting protein 1 Potassium voltage-gated channel interacting protein 2 Potassium voltage-gated channel interacting protein 3 Potassium voltage-gated channel subfamily D member 1 Potassium voltage-gated channel subfamily D member 2 Potassium voltage-gated channel subfamily D member 3	A0A3Q1LV43 A0A3Q1M5I5 A0A3Q1M784 F1MVI5 F1MY95 Q2KI69 Q52PG9	KCND1 KCND2 KCND3 KCNIP1 KCNIP2 KCNIP3 KCNIP4	Bos taurus (cattle)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 CUL2 protein Elongin-C Endothelial PAS domain protein 1 Hypoxia inducible factor 3 subunit alpha Hypoxia-inducible factor 1-alpha LIM domain-containing protein 1 LIM domain-containing protein ajuba Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) Ubiquitin conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WT1 interacting protein hypoxia-inducible factor-proline dioxygenase hypoxia-inducible factor-proline dioxygenase hypoxia-inducible factor-proline dioxygenase	A0A3Q1LUX2 A0A3Q1M2B6 A0A3Q1M5N0 A0A3Q1MIU5 A0A3Q1MKG5 A0A452DI44 A0A452DIY4 A0JND0 A7MBA0 A7MBA2 E1BD83 E1BKA3 E1BP33 F1MBI1 F1MLV1 F1MWE0 F1MXE4 F1MYH8 F1N6Z0 G5E589 G5E5X0 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q08DE9 Q17QP9 Q1RMX2 Q2KI42 Q2KII4 Q2KJ25 Q2KJ46 Q2KJE7 Q2TA10 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZ32 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	AJUBA CUL2 EGLN1 EGLN2 EGLN3 ELOC EPAS1 HIF1A HIF3A JUB LIMD1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SUG1 TCEB1 TCEB2 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBCEP1 UBCEP2 UBCH4 UBCH5B UBE2D1 UBE2D2 UBE2D3 WTIP	Bos taurus (cattle)
SUMOylation of immune response proteins	Inhibitor of nuclear factor kappa B kinase subunit epsilon NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappaB transcription factor p65 subunit NFKB2 protein PIAS3 protein PIAS4 protein RING-type E3 ubiquitin transferase Rad60/SUMO-like domain-containing protein Rad60/SUMO-like domain-containing protein SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 3	A0A3Q1LUL4 A0A3Q1M2W5 A1XG22 A4FV15 A6QQU9 A7MBB7 F1MQ36 F1N329 G3MZL6 Q17QV3 Q8WNW7 Q95KU9	IKBKE IKBKG NEMO NFKB2 NFKBIA PIAS3 PIAS4 RELA SUMO3 TOPORS bIkBa	Bos taurus (cattle)
TRAF6 mediated NF-kB activation	Advanced glycosylation end-product specific receptor Amyloid-beta A4 protein High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappa-B inhibitor-interacting Ras-like protein 2 NF-kappaB transcription factor p65 subunit NFKB inhibitor interacting Ras like 1 NFKB2 protein Nuclear factor NF-kappa-B p105 subunit Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta Protein S100-A12 Protein S100-B	A0A3Q1LUG2 A0A3Q1LZM4 A1XG22 A7MBB7 F1MKW9 F1N306 P02638 P10103 P79105 Q0IIB2 Q1JPF1 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	AGER APP CAAF1 CHUK HMG1 HMGB1 IKBKB IKBKG IKKA NEMO NFKB1 NFKB2 NFKBIA NFKBIB NKIRAS1 NKIRAS2 RELA S100A12 S100B bIkBa	Bos taurus (cattle)
TAK1-dependent IKK and NF-kappa-B activation	Advanced glycosylation end-product specific receptor Amyloid-beta A4 protein High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappa-B inhibitor-interacting Ras-like protein 2 NF-kappaB transcription factor p65 subunit NFKB inhibitor interacting Ras like 1 NFKB2 protein Nuclear factor NF-kappa-B p105 subunit Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta Protein S100-A12 Protein S100-B	A0A3Q1LUG2 A0A3Q1LZM4 A1XG22 A7MBB7 F1MKW9 F1N306 P02638 P10103 P79105 Q0IIB2 Q1JPF1 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	AGER APP CAAF1 CHUK HMG1 HMGB1 IKBKB IKBKG IKKA NEMO NFKB1 NFKB2 NFKBIA NFKBIB NKIRAS1 NKIRAS2 RELA S100A12 S100B bIkBa	Bos taurus (cattle)
Bicarbonate transporters	Adenosylhomocysteinase 3 Anion exchange protein Anion exchange protein Anion exchange protein Anion exchange protein Anion exchange protein Anion exchange protein Anion exchange protein Anion exchange protein Sodium-driven chloride bicarbonate exchanger	A0A3Q1LUF6 A0A3Q1M051 A6QLP2 E1BBH7 E1BIN2 E1BKK3 F1MVR5 F6QPG2 G3MWI1 Q32LP4	AHCYL2 SLC4A1 SLC4A10 SLC4A2 SLC4A3 SLC4A4 SLC4A5 SLC4A7 SLC4A8 SLC4A9	Bos taurus (cattle)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor receptor Klotho	A0A3Q1LUE0 E1BAI2 E1BJU2	FGF23 FGFR1 KL	Bos taurus (cattle)
FGFR1c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q1LUE0 A0MTF4 D8KXU9 E1BHC1 E1BJU2 E1BP37 F1N6G8 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF17 FGF2 FGF20 FGF23 FGF4 FGF4A FGF5 FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 Fgf4 HBGF-1	Bos taurus (cattle)
FGFR1b ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor	A0A3Q1LUE0 A0A3Q1NAV6 E1BGY3 P03968 P03969	AFGF FGF1 FGF10 FGF2 FGF3 FGF5C FGFA FGFR1 HBGF-1	Bos taurus (cattle)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho	A0A3Q1LUE0 A0A3Q1NAV6 A0MTF4 D8KXU9 E1BAI2 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MYF9 F1N6G8 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF10 FGF17 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF5 FGF5C FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 Fgf4 HBGF-1 KL PLCG1	Bos taurus (cattle)
Downstream signaling of activated FGFR1	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 1 Fibronectin leucine rich transmembrane protein 2 Fibronectin leucine rich transmembrane protein 3 Klotho	A0A3Q1LUE0 A0A3Q1NAV6 A0MTF4 D8KXU9 E1BAI2 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MVT1 F1N0R7 F1N6G8 G3MXR4 G3MY74 G3XGD3 P03968 P03969	AFGF FGF1 FGF10 FGF17 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF5 FGF5C FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 FLRT1 FLRT2 FLRT3 Fgf4 HBGF-1 KL	Bos taurus (cattle)
PI-3K cascade:FGFR1	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated-binding protein 1 Growth factor receptor-bound protein 2 Klotho Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type	A0A3Q1LUE0 A0A3Q1NAV6 A0MTF4 A6QLU3 D8KXU9 E1B7I9 E1BAI2 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1N339 F1N6G8 G3MXR4 G3XGD3 P03968 P03969 P23727 P32871 Q3T0F9	AFGF FGF1 FGF10 FGF17 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF5 FGF5C FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 FRS2 Fgf4 GAB1 GRB2 HBGF-1 KL PIK3CA PIK3R1 PTPN11	Bos taurus (cattle)
SHC-mediated cascade:FGFR1	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase NRas Growth factor receptor-bound protein 2 Klotho SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A3Q1LUE0 A0A3Q1NAV6 A0MTF4 A5D7R9 D8KXU9 E1BAI2 E1BGY3 E1BHC1 E1BJU2 E1BMX0 E1BP37 F1N6G8 F1N7C3 G3MXR4 G3XGD3 P03968 P03969 Q0IIE2 Q3T0F9	AFGF FGF1 FGF10 FGF17 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF5 FGF5C FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 Fgf4 GRB2 HBGF-1 KL KRAS NRAS SHC1 SOS1	Bos taurus (cattle)
FRS-mediated FGFR1 signaling	FRS3 protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase NRas Growth factor receptor-bound protein 2 Klotho SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A3Q1LUE0 A0A3Q1NAV6 A0MTF4 A5D7R9 A6H792 D8KXU9 E1B7I9 E1BAI2 E1BGY3 E1BHC1 E1BJU2 E1BMX0 E1BP37 F1N339 F1N6G8 F1N7C3 G3MXR4 G3XGD3 P03968 P03969 Q3T0F9	AFGF FGF1 FGF10 FGF17 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF5 FGF5C FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 FRS2 FRS3 Fgf4 GRB2 HBGF-1 KL KRAS NRAS PTPN11 SOS1	Bos taurus (cattle)
Glycosphingolipid biosynthesis	Beta-1,4 N-acetylgalactosaminyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Ceramide kinase Gal-NAc6S Galactoside alpha-(1,2)-fucosyltransferase 1 Hexosyltransferase Hexosyltransferase L-Fucosyltransferase Lactosylceramide 4-alpha-galactosyltransferase Lactosylceramide alpha-2,3-sialyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 UDP glycosyltransferase 8 ceramide glucosyltransferase	A0A3Q1LUC6 A0A3Q1MPZ8 A0A452DJH9 A4IFB0 E1BCQ2 F1MUJ7 F1MUS1 F1MXN8 F1N2J4 F1N7G6 F6Q1T7 G3MXL8 G3MZ03 Q08DR4 Q2HJA3 Q58DI2 Q6H8M9	A4GALT B3GALT4 B3GNT5 B4GALNT1 B4GALT5 B4GALT6 CERK FUT1 FUT2 GALGT ST3GAL2 ST3GAL3 ST3GAL5 ST6GALNAC5 ST6GALNAC6 ST8SIA5 UGCG UGT8 siat4B	Bos taurus (cattle)

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