GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **326 - 350** of **557** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Alternative complement activation	Complement C3 Complement factor B Complement factor D Granzyme M	E1BP32 P81187 Q2UVX4 Q3T0A3	BF C3 CFB CFD GZMM	Bos taurus (cattle)
Sensory perception of sweet, bitter, and umami (glutamate) taste	G protein subunit beta 3 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(t) subunit alpha-3 Inositol 1,4,5-trisphosphate receptor Taste 1 receptor member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2	A0A3Q1LRA2 A0A3Q1LZA1 A0A3Q1MIP5 A0A3Q1ML22 A0A3Q1N0Q7 A0A3Q1NGS8 A0A3Q1NND8 E1B8B7 E1B8Q3 E1BKE7 E1BPM8 F1MP17 F1MVK0 F1N5V2 P0C7Q4 P62871 Q2ABB3 Q2ABC0 Q2ABC3 Q2ABC4 Q2ABC5	GNAT3 GNB1 GNB3 GNG13 ITPR3 LOC782957 T2R10C TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R16 TAS2R3 TAS2R39 TAS2R4 TAS2R40 TAS2R46 TAS2R7 TAS2R8	Bos taurus (cattle)	G58161NS
Calmodulin induced events	Beta-adrenergic receptor kinase 1 Calmodulin-like EF-hand domain-containing protein Protein kinase C delta type	A0A3Q1MR28 A0A3Q1MRR6 F1MLH6 P21146	ADRBK1 CALM GRK2 PRKCD	Bos taurus (cattle)
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 G protein subunit alpha L adenylate cyclase	A0A3Q1M3D6 A0A3Q1MA58 E1B9K3 E1BHU9 E1BM79 E1BQ12 F1MJV4 F1MPC9 P19754	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 GNAL	Bos taurus (cattle)
Orc1 removal from chromatin	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cell division control protein Chromatin licensing and DNA replication factor 1 Cullin 1 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA helicase MCM8 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 ORC5L protein Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 6 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta S-phase kinase-associated protein 1 SKP2 protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A140T8C7 A0A3Q1LHC9 A0A3Q1LIW5 A0A3Q1LR25 A0A3Q1MVB0 A0A452DI44 A0A452DIY4 A4FUD9 A5PJS5 A6H7F8 A7MB09 A7MBA2 E1BD83 E1BFZ9 E1BH89 E1BPX4 F1MBI1 F1MLV1 F1MVR8 F1MWE0 F1MXE4 F1MYD0 F1MYH8 F1N6W8 F1N6Z0 G5E589 G8JKW1 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2HJF3 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q2YDI2 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZBH9 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0 Q5E9Y0	CCNA1 CCNA2 CDC6 CDK2 CDKN2 CDT1 CUL1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 ORC1 ORC2 ORC3 ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SKP1 SKP1A SKP2 SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
Digestion	Guanylate cyclase activator 2B Guanylate cyclase Guanylin PIR protein alkaline phosphatase	A6QQH1 E1BIM0 E1BIM1 E1BJE3 F1N5B2	GUCA2A GUCA2B GUCY2C LOC516378 PIR	Bos taurus (cattle)
Prednisone ADME	11-beta-hydroxysteroid dehydrogenase type 2 AKR1C4 protein ATP binding cassette subfamily B member 1 Albumin Corticosteroid-binding globulin Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Dihydrodiol dehydrogenase 3 NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Prostaglandin F synthase 2 UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase	A0A140T897 A0A3Q1LWZ2 A0A3Q1LYU5 A0A3Q1LZ03 A0A3Q1M423 A0A3Q1MB23 A0A3Q1MIN6 E1BBB3 E1BF81 E1BG58 E1BJU8 E1BP71 F1MFF6 F1MNC0 F1MT58 F1N3U0 G3X6I4 M0QW04 M0QW14 M0QW25 P52897 P52898 Q29RV2 Q3T047 Q3ZBG2	ABCB1 AKR1C4 ALB CBG CYP3A28 CYP3A4 CYP3A5 CYP3A74 CYP3A76 HSD11B2 LOC100138004 LOC100138908 LOC100296421 LOC506594 LOC538060 LOC782061 LOC782884 LOC785762 SERPINA6 UGT1A6 UGT2B10	Bos taurus (cattle)
Endogenous sterols	Adrenodoxin, mitochondrial Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor CYP39A1 protein Cholesterol 7-alpha-monooxygenase Cholesterol side-chain cleavage enzyme, mitochondrial Cytochrome P450 family 1 subfamily B member 1 Cytochrome P450 family 27 subfamily A member 1 Cytochrome P450 family 4 subfamily V member 2 Cytochrome P450, family 46, subfamily A, polypeptide 1 Ferredoxin-2, mitochondrial Lanosterol 14-alpha demethylase NADPH Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Pro-opiomelanocortin Retinoic acid receptor RXR Steroid 21-hydroxylase aromatase steroid 11beta-monooxygenase steroid 11beta-monooxygenase steroid 11beta-monooxygenase	A0A3Q1LKX3 A3KMX9 A6H722 E1BM29 E1BPY4 F1MG97 F1ML85 F1MNG1 F1MTT1 F1MU47 F1MWH3 F1MX52 F1MYL2 F1N3Z7 F2Z4F2 F6QQE8 G3N0C2 P00191 P00257 P01190 Q05B51 Q08DD0 Q148K8 Q4PJW3	ADX AHR ARNT ARNT2 CYP11A1 CYP11B1 CYP19A1 CYP1B1 CYP21 CYP21A1 CYP21A2 CYP27A1 CYP39A1 CYP46A1 CYP4V2 CYP51A1 CYP7A1 FDX1 FDX1L FDX2 FDXR LOC112449566 NCOA1 NCOA2 NR1H4 POMC RXRA	Bos taurus (cattle)
Glycosphingolipid biosynthesis	Beta-1,4 N-acetylgalactosaminyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Ceramide kinase Gal-NAc6S Galactoside alpha-(1,2)-fucosyltransferase 1 Hexosyltransferase Hexosyltransferase L-Fucosyltransferase Lactosylceramide 4-alpha-galactosyltransferase Lactosylceramide alpha-2,3-sialyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 UDP glycosyltransferase 8 ceramide glucosyltransferase	A0A3Q1LUC6 A0A3Q1MPZ8 A0A452DJH9 A4IFB0 E1BCQ2 F1MUJ7 F1MUS1 F1MXN8 F1N2J4 F1N7G6 F6Q1T7 G3MXL8 G3MZ03 Q08DR4 Q2HJA3 Q58DI2 Q6H8M9	A4GALT B3GALT4 B3GNT5 B4GALNT1 B4GALT5 B4GALT6 CERK FUT1 FUT2 GALGT ST3GAL2 ST3GAL3 ST3GAL5 ST6GALNAC5 ST6GALNAC6 ST8SIA5 UGCG UGT8 siat4B	Bos taurus (cattle)
Interaction With Cumulus Cells And The Zona Pellucida	Beta-1,4-galactosyltransferase 1 Disintegrin and metalloproteinase domain-containing protein 2 Hyaluronidase Oviduct-specific glycoprotein Zona pellucida sperm-binding protein 2 Zona pellucida sperm-binding protein 3 Zona pellucida sperm-binding protein 4	A0A3Q1MHW1 A0A3S5ZPD7 A6H6X7 F1MZM9 G1K1H0 P08037 Q9BH11	ADAM2 B4GALT1 GALT GGTB2 LOC509761 OVGP1 ZP2 ZP3 ZP4 ZPB	Bos taurus (cattle)
Acyl chain remodelling of PS	Cytosolic phospholipase A2 LPCAT4 protein Lysophospholipid acyltransferase 5 Membrane bound O-acyltransferase domain containing 1 Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein PLA2G12A protein Phospholipase A2, group XVI Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Secretory phospholipase A2 receptor	A0A3Q1LWY5 A0A3Q1LYR5 A0A3Q1MI45 A0A3Q1MNU5 A0A3Q1NMD6 A0JNE8 A4IFJ5 A5D7L0 E1BGU4 E1BNI4 F1MFD9 F1MG30 F1MNU5 F1MSG5 G8JL05 P00593 P49259 Q56JZ2	CPLA2 LOC613966 LPCAT3 LPCAT4 MBOAT1 OSBPL10 OSBPL5 OSBPL8 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G4 PLA2G4A PLA2G4D PLA2G4E PLA2G4F PLA2R1	Bos taurus (cattle)
EPH-ephrin mediated repulsion of cells	72 kDa type IV collagenase EPH receptor B6 Ephrin B2 Ephrin B3 Ephrin type-B receptor 3 Ephrin-B1 Gamma-secretase subunit APH-1 Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Matrix metalloproteinase-9 Nicastrin Presenilin-1 Presenilin-2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A3Q1LNM1 A0A3Q1LXH4 A0A3Q1MBH7 A0A3Q1MDC6 A0A3Q1MQP9 A0JNB0 A1L570 A7MB57 E1BBD2 E1BIE4 E1BIM8 F1MII5 F1MKH8 F1ML02 F1N0M5 F1N261 F1N3R6 F1N5D4 P52176 Q5G235 Q9XT96 Q9XT97	APH1A APH1B EFNB1 EFNB2 EFNB3 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 FYN LYN MMP2 MMP9 NCSTN PEN2 PSEN1 PSEN2 PSENEN SRC VAV2 VAV3 YES1	Bos taurus (cattle)
Cellular hexose transport	Fibroblast growth factor Major facilitator superfamily domain containing 4B Na+/glucose cotransporter 2 Sodium/glucose cotransporter 1 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2 member 11 Solute carrier family 2 member 6 Solute carrier family 2 member 8 Solute carrier family 2 member 9 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 45 member 3 Solute carrier family 5 member 4 Solute carrier family 5 member 9	A0A3Q1MA30 A0A3Q1MQD9 A2VDL2 E1B749 E1BDA6 E1BLB0 E1BMB9 F1MD24 F1MIV2 F1MPC8 F1MRS7 F1MZY9 F1N4B2 P27674 P58351 Q27994 Q6R4Q5 Q6XUI1	FGF21 FGF8C GLUT1 GLUT2 GLUT4 MFSD4B SGLT5 SLC2A1 SLC2A11 SLC2A12 SLC2A2 SLC2A3 SLC2A4 SLC2A6 SLC2A8 SLC2A9 SLC45A3 SLC5A1 SLC5A10 SLC5A2 SLC5A4 SLC5A9	Bos taurus (cattle)	G58161NS G70323CJ
Cross-presentation of soluble exogenous antigens (endosomes)	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 CD207 molecule Fc fragment of IgG receptor Ia Mannose receptor C type 2 Mannose receptor C-type 1 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta	A0A3Q1M5H7 A0A3S5ZP99 A0A452DI44 A0A452DIY4 A7MBA2 E1BB51 E1BD83 F1MBI1 F1MLV1 F1MWE0 F1MWM8 F1MXE4 F1MYH8 F1N6Z0 G5E589 P33672 P56701 P62194 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	CD207 FCGR1A MRC1 MRC2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 SUG1 TRAP2	Bos taurus (cattle)
Activation of C3 and C5	Complement C2 Complement C3 Complement C5 Complement component 4A Complement factor B Uncharacterized protein	E1BH06 F1MVK1 F1MY85 P81187 Q2UVX4 Q3SYW2	BF C2 C3 C4A C5 CFB LOC107131209	Bos taurus (cattle)
RIP-mediated NFkB activation via ZBP1	ATP-dependent RNA helicase A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappa-B inhibitor-interacting Ras-like protein 2 NF-kappaB transcription factor p65 subunit NFKB inhibitor interacting Ras like 1 NFKB2 protein Nuclear factor NF-kappa-B p105 subunit Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	A0A3Q1LZM4 A0A452DHW6 A1XG22 A7MBB7 F1MKW9 Q0IIB2 Q1JPF1 Q28141 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	CHUK DDX9 DHX9 IKBKB IKBKG IKKA MYD88 NDH2 NEMO NFKB1 NFKB2 NFKBIA NFKBIB NKIRAS1 NKIRAS2 RELA bIkBa	Bos taurus (cattle)
Aspartate and asparagine metabolism	Acidic amino acid decarboxylase GADL1 Asparagine synthetase [glutamine-hydrolyzing] Aspartate aminotransferase, cytoplasmic Aspartate aminotransferase, mitochondrial Aspartoacylase Folate hydrolase 1B N-acetylated alpha-linked acidic dipeptidase 2 Solute carrier family 25 member 12	A0A3Q1M9V5 A6QM00 F1MGS8 F1MUP1 F1MUZ8 P12344 P33097 Q1LZA3	ASNS ASPA FOLH1B GADL1 GOT1 GOT2 NAALAD2 SLC25A12	Bos taurus (cattle)
Assembly of active LPL and LIPC lipase complexes	Angiopoietin like 8 Angiopoietin-like 3 Angiopoietin-related protein 4 Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Hepatic triacylglycerol lipase Lipase maturation factor Lipase maturation factor Lipoprotein lipase Proprotein convertase subtilisin/kexin type 5 Proprotein convertase subtilisin/kexin type 6 furin	A0A3Q1LU66 A0A3Q1MCD7 A0A3Q1MPP4 B0JYR0 E1BKI5 F1MCT1 G3X879 P11151 Q2KJ51 Q2KJB3 Q3SZ79	ANGPTL3 ANGPTL4 ANGPTL8 FURIN GPIHBP1 LIPC LMF1 LMF2 LPL PCSK5 PCSK6	Bos taurus (cattle)
COPI-mediated anterograde transport	ADP ribosylation factor GTPase activating protein 1 ADP-ribosylation factor 1 ADP-ribosylation factor 3 ADP-ribosylation factor 4 ADP-ribosylation factor GTPase-activating protein 2 ADP-ribosylation factor GTPase-activating protein 3 ADP-ribosylation factor Actin-related protein 10 Alpha-centractin BET1-like protein Bet1 golgi vesicular membrane trafficking protein Beta-soluble NSF attachment protein CD55 molecule (Cromer blood group) CD59 glycoprotein Coatomer subunit alpha Coatomer subunit beta' Coatomer subunit beta Coatomer subunit delta Coatomer subunit epsilon Coatomer subunit gamma-2 Coatomer subunit gamma Coatomer subunit zeta-1 Coatomer subunit zeta Component of oligomeric golgi complex 5 Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 Conserved oligomeric Golgi complex subunit 8 Cytoplasmic dynein 1 intermediate chain 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein cytoplasmic 1 heavy chain 1 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light intermediate chain Dynein light intermediate chain ER lumen protein-retaining receptor 1 ER lumen protein-retaining receptor 2 ER lumen protein-retaining receptor F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha Folate receptor 3 Gamma-soluble NSF attachment protein General vesicular transport factor p115 Golgi SNAP receptor complex member 1 Golgi SNAP receptor complex member 2 Golgi brefeldin A resistant guanine nucleotide exchange factor 1 Golgi reassembly stacking protein 1 Golgin A2 Golgin B1 Insulin NSF attachment protein alpha Ras-related protein Rab-1A Spectrin alpha, erythrocytic 1 Spectrin alpha, non-erythrocytic 1 Spectrin beta chain Spectrin beta chain Spectrin beta, non-erythrocytic 4 Synaptobrevin homolog YKT6 Syntaxin-5 TMED7 protein Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 9 Transmembrane p24 trafficking protein 3 Transmembrane protein 115 Vesicle-fusing ATPase small monomeric GTPase	A0A140T856 A0A140T886 A0A3Q1LNC8 A0A3Q1LQX2 A0A3Q1LSE5 A0A3Q1LTM9 A0A3Q1LWK0 A0A3Q1LXI8 A0A3Q1LYE2 A0A3Q1M072 A0A3Q1M3Y3 A0A3Q1M5V0 A0A3Q1M762 A0A3Q1MJE3 A0A3Q1MUW5 A0A3Q1MWA3 A0A3Q1N147 A0A3Q1NDZ1 A0A3Q1NEU9 A0A452DKB6 A0JN39 A2VE21 A4FUA8 A4FUB8 A4IFP7 A4IFT6 A5PJB2 E1BBI8 E1BGA6 E1BJK5 E1BK29 E1BKZ5 E1BLT3 E1BMC4 E1BMN5 F1MBQ0 F1MI54 F1MKE9 F1MLE3 F1MMQ8 F1MQ89 F1N5R4 F2Z4F0 F6Q334 G3N173 P33946 P35604 P35605 P41541 P53619 P61285 P81126 P84080 Q08DB5 Q0P5A1 Q148G7 Q17R07 Q28104 Q29RQ3 Q2KII9 Q2KJ37 Q2TBU3 Q32KS3 Q32PA1 Q3MHG0 Q3MHP8 Q3MHR3 Q3SZF2 Q3T000 Q3T133 Q3ZBD2 Q3ZCF0 Q5E971 Q5E997 Q5E9I6	ACTR10 ACTR1A ARCN1 ARF1 ARF3 ARF4 ARF5 ARFGAP1 ARFGAP2 ARFGAP3 ARP10 BET1 BET1L CAPZA1 CAPZA2 CAPZA3 CD55 CD59 COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 COPA COPB1 COPB2 COPD COPE COPE1 COPG1 COPG2 COPZ COPZ1 COPZ2 DCTN1 DCTN2 DCTN3 DCTN4 DCTN5 DCTN6 DNCL1 DYNC1H1 DYNC1I1 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 FOLR3 GBF1 GOLGA2 GOLGB1 GORASP1 GOSR1 GOSR2 INS KDELR KDELR1 KDELR2 KDELR3 NAPA NAPB NAPG NSF RAB1A RAB1B SNAPB SPTA1 SPTAN1 SPTB SPTBN2 SPTBN4 STX5 TMED10 TMED3 TMED7 TMED9 TMEM115 TMP21 USO1 VDP YKT6	Bos taurus (cattle)
FGFR3c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Polypeptide N-acetylgalactosaminyltransferase	A0A3Q1MPT9 A0MTF4 D8KXU9 E1BBP1 E1BJU2 E1BP37 F1MHC6 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF4 FGF4A FGF4C FGF5 FGF6A FGF8 FGF9 FGFA FGFR3 Fgf4 GALNT3 HBGF-1	Bos taurus (cattle)
RUNX1 regulates transcription of genes involved in differentiation of HSCs	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 CDK-activating kinase assembly factor MAT1 Core-binding factor subunit beta Cyclin-H Cyclin-dependent kinase 7 E3 ubiquitin-protein ligase GATA binding protein 1 GATA binding protein 3 Histone-lysine N-methyltransferase LIM domain binding 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Rhombotin-1 Rhombotin-2 Runt-related transcription factor TAL bHLH transcription factor 1, erythroid differentiation factor Transcription factor 12 Transcription factor E2-alpha Tumor protein p73 Tyrosine-protein kinase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Yes1 associated transcriptional regulator	A0A3Q1LI98 A0A3Q1LQN2 A0A3Q1M323 A0A3Q1MGB0 A0A3Q1ML13 A0A452DI44 A0A452DI60 A0A452DIY4 A7MBA2 E1B9S8 E1BAD4 E1BAU0 E1BD83 E1BI59 F1MBI1 F1MGQ5 F1MHA1 F1MK73 F1MLV1 F1MV33 F1MWE0 F1MXE4 F1MYH8 F1N6Z0 G3X6J7 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q08DX5 Q0P5B3 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SX39 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	ABL1 CBFB CCNH CDK7 GATA1 GATA3 ITCH KMT2A LDB1 LMO1 LMO2 MNAT1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RBTN1 RPS27A RUNX1 SUG1 TAL1 TCF12 TCF3 TP73 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YAP1	Bos taurus (cattle)
Acyl chain remodelling of PC	Cytosolic phospholipase A2 LPCAT4 protein Lysophosphatidylcholine acyltransferase 1 Lysophosphatidylcholine acyltransferase 2 Lysophospholipid acyltransferase 5 Lysoplasmalogenase TMEM86B Membrane bound O-acyltransferase domain containing 2 PLA2G12A protein Patatin like phospholipase domain containing 8 Phospholipase A2, group XVI Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1 Secretory phospholipase A2 receptor phospholipase A2 phospholipase A2	A0A3Q1LYR5 A0A3Q1MNU5 A0A3Q1MPE0 A0A3Q1NMD6 A0JNE8 A4IFJ5 A5D7L0 E1BB89 E1BE78 E1BEM2 E1BGU4 F1MG30 F1MH02 F1MNU5 F1MSG5 F1MTK4 G8JL05 P00593 P49259 Q3T0W0 Q56JZ2 Q9GL30	CPLA2 LOC613966 LPCAT1 LPCAT2 LPCAT3 LPCAT4 MBOAT2 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G3 PLA2G4 PLA2G4A PLA2G4D PLA2G4E PLA2G4F PLA2G6 PLA2R1 PLBD1 PNPLA8 TMEM86B	Bos taurus (cattle)
Lysosome Vesicle Biogenesis	ADP-ribosylation factor 1 AP complex subunit beta AP complex subunit beta AP complex subunit sigma AP-1 complex subunit gamma AP-1 complex subunit gamma AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-1 complex subunit sigma-1A AP-1 complex subunit sigma-2 AP-4 complex subunit mu-1 AP-4 complex subunit sigma-1 Adaptor related protein complex 4 subunit epsilon 1 Amyloid-beta A4 protein Beta-arrestin-1 Biogenesis of lysosome-related organelles complex 1 subunit 1 Cathepsin Z Cation-dependent mannose-6-phosphate receptor Charged multivesicular body protein 2a Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Clavesin-1 Clavesin-2 Deoxyribonuclease-2-alpha Hepatocyte growth factor-regulated tyrosine kinase substrate N-acetylglucosamine-6-sulfatase SH3 domain containing GRB2 like 2, endophilin A1 Thioredoxin domain containing 5 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 8	A0A3Q1LMK0 A0A3Q1LUG2 A0A3Q1LUG9 A0A3Q1LWC6 A0A3Q1M481 A0A3Q1M952 E1BE20 E1BHP4 E1BNA3 F1MXZ0 F1MZ33 F6QYT8 P04973 P04975 P05689 P11456 P17870 P49951 P63026 P84080 Q08DX1 Q0V8S0 Q1JQ98 Q29RY8 Q2KJ81 Q2NKW0 Q3SYW1 Q3T0U5 Q3T0Y8 Q3ZBB6 Q3ZBS3	AP1B1 AP1G1 AP1G2 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 AP4B1 AP4E1 AP4M1 AP4S1 APP ARF1 ARRB1 BLOC1S1 CHMP2A CLTA CLTB CLTC CLTLB CLVS1 CLVS2 CTSZ DNASE2 GNS HGS M6PR SH3GL2 SYB2 TXNDC5 VAMP2 VAMP8	Bos taurus (cattle)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho	A0A3Q1LUE0 A0A3Q1NAV6 A0MTF4 D8KXU9 E1BAI2 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MYF9 F1N6G8 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF10 FGF17 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF5 FGF5C FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 Fgf4 HBGF-1 KL PLCG1	Bos taurus (cattle)
COPI-independent Golgi-to-ER retrograde traffic	1-acylglycerol-3-phosphate O-acyltransferase 3 Actin-related protein 10 Alpha-centractin BICD cargo adaptor 1 BICD cargo adaptor 2 Cytoplasmic dynein 1 intermediate chain 1 Cytosolic phospholipase A2 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein cytoplasmic 1 heavy chain 1 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light intermediate chain Dynein light intermediate chain F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha Platelet-activating factor acetylhydrolase IB subunit alpha1 Platelet-activating factor acetylhydrolase IB subunit alpha2 Platelet-activating factor acetylhydrolase IB subunit alpha Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase RAB3 GTPase activating non-catalytic protein subunit 2 RAB6A, member RAS onco family RAB6B, member RAS onco family Rab3 GTPase-activating protein catalytic subunit Ras-related protein Rab-18 phospholipase A2	A0A3Q1M3Y3 A0A3Q1M986 A0A3Q1MBS7 A0A3Q1MUW5 A0A3Q1NEU9 A0A452DHU1 A0A452DIB1 A4FUA8 A4FUE5 A4IFJ5 A5D7P3 E1BB89 E1BBI8 F1MBQ0 F2Z4F0 G3N061 G3N3P0 G5E5P6 G5E601 P61285 P68401 Q07537 Q0P5A1 Q148G7 Q29460 Q29RQ3 Q2KII9 Q32KS3 Q3MHR3 Q3ZBD2 Q3ZCF0 Q5E997	ACTR10 ACTR1A AGPAT3 ARP10 BICD1 BICD2 CAPZA1 CAPZA2 CAPZA3 CPLA2 DCTN1 DCTN2 DCTN3 DCTN4 DCTN5 DCTN6 DNCL1 DYNC1H1 DYNC1I1 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 GALNT1 GALNT2 LIS1 PAFAH1B1 PAFAH1B2P68402 PAFAH1B3 PAFAHB PAFAHG PLA2G4 PLA2G4A PLA2G6 RAB18 RAB3GAP1 RAB3GAP2 RAB6A RAB6B	Bos taurus (cattle)

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