GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **557** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
Synthesis of PA	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha 1-acyl-sn-glycerol-3-phosphate acyltransferase delta 1-acyl-sn-glycerol-3-phosphate acyltransferase 1-acylglycerol-3-phosphate O-acyltransferase 3 1-acylglycerol-3-phosphate O-acyltransferase 5 1-acylglycerol-3-phosphate O-acyltransferase 6 (Lysophosphatidic acid acyltransferase, zeta) Cytosolic phospholipase A2 DDHD domain containing 1 DDHD domain containing 2 Dihydroxyacetone phosphate acyltransferase Glycerol-3-phosphate acyltransferase 1, mitochondrial Glycerol-3-phosphate acyltransferase 2, mitochondrial Glycerol-3-phosphate acyltransferase 3 Glycerol-3-phosphate dehydrogenase [NAD(+)] Glycerol-3-phosphate dehydrogenase [NAD(+)] Glycerol-3-phosphate dehydrogenase, mitochondrial LPCAT4 protein Lipase H Lysophosphatidic acid phosphatase type 6 Lysophosphatidylcholine acyltransferase 1 Mitochondrial cardiolipin hydrolase Mitoguardin 1 Mitoguardin 2 PLA2G12A protein Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase Phospholipase Secretory phospholipase A2 receptor alkaline phosphatase	A0A3Q1LQH8 A0A3Q1MFB9 A0A3Q1MFP5 A0A3Q1MMR4 A0A3Q1MNU5 A0A3S5ZPU2 A0A452DJJ3 A0JNE8 A4IFJ5 A5D7L0 A6H757 A6H7D4 A6QLU1 A6QQR7 E1BE10 E1BGF8 E1BGU4 E1BJE3 F1MDT6 F1MG30 F1MLW9 F1MNB3 F1MSG5 F1MSS2 F1MTK4 F1MXA8 F1MZS9 G5E5P6 P00593 P49259 Q1JPG0 Q56JZ2 Q5EA60 Q95JH2	ACP6 AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT5 AGPAT6 CPLA2 DDHD1 DDHD2 FAM73B GNPAT GPAM GPAT2 GPAT3 GPAT4 GPD1 GPD1L GPD2 LIPH LOC516378 LOC613966 LPCAT1 LPCAT4 MIGA1 MIGA2 PLA2G12A PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G4 PLA2G4A PLA2G4D PLA2R1 PLD1 PLD2 PLD6	Bos taurus (cattle)
Neutrophil degranulation	1-acyl-sn-glycerol-3-phosphate acyltransferase 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 7 ADP ribosylation factor like GTPase 8A ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase AMP deaminase AP-1 complex subunit mu-1 AP-2 complex subunit alpha-2 ARSB protein ATP binding cassette subfamily A member 13 ATP-citrate synthase ATP-dependent 6-phosphofructokinase, liver type ATPase family AAA domain-containing protein 3 Acetyl-CoA acyltransferase 1 Acid ceramidase Actin-related protein 10 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Acylamino-acid-releasing enzyme Adenine phosphoribosyltransferase Adenylyl cyclase-associated protein Adhesion G protein-coupled receptor E3 Adhesion G protein-coupled receptor E5 Adhesion G protein-coupled receptor G3 Aldehyde dehydrogenase family 3 member B1 Alpha-1,4 glucan phosphorylase Alpha-1-acid glycoprotein Alpha-1-antiproteinase Alpha-1B-glycoprotein Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-galactosidase Amine oxidase Annexin A2 Anoctamin Apoptotic protease-activating factor 1 Arachidonate 5-lipoxygenase Arginase-1 Armadillo repeat-containing protein 8 Arylsulfatase A Aspartylglucosaminidase Azurocidin 1 BIN2 protein Bactericidal permeability-increasing protein Beta-1,4-galactosyltransferase 1 Beta-2-microglobulin Beta-centractin Beta-galactosidase Beta-glucuronidase Beta-hexosaminidase Beta-mannosidase Bis(5'-adenosyl)-triphosphatase ENPP4 Bone marrow stromal antigen 2 C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 2 C-type lectin domain containing 5A C-type lectin domain family 4 member D C-type lectin domain family 6 member A C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 CALML5 protein CD177 molecule CD44 antigen CD55 molecule (Cromer blood group) CD58 molecule CD59 glycoprotein CD63 antigen CD68 molecule CD93 molecule CKLF like MARVEL transmembrane domain containing 6 COMM domain containing 9 COMM domain-containing protein 3 CPNE3 protein Calcium activated nucleotidase 1 Calcium release activated channel regulator 2A Calcium-binding protein 39 Calpain-1 catalytic subunit Calponin-2 Carboxypeptidase Carcinoembryonic antigen related cell adhesion molecule 1 Carcinoembryonic antigen related cell adhesion molecule 1 Casein kinase II subunit beta Catalase Cathelicidin-4 Cathepsin B Cathepsin D Cathepsin S Cathepsin Z Cell cycle control protein 50A Cellular repressor of E1A stimulateds 1 Centrosomal protein 290 Chitinase-3-like protein 1 Choline transporter-like protein 2 Chromosome 7 C1orf35 homolog Coactosin-like protein Coatomer subunit beta Complement C3 Complement factor D Complement factor properdin Copine-1 Cullin-associated NEDD8-dissociated protein 1 Cyclin-dependent kinase 13 Cystatin B (stefin B) Cystatin-C Cysteine-rich and transmembrane domain-containing protein 1 Cysteine-rich secretory protein 2 Cysteine-rich secretory protein LCCL domain-containing 2 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoskeleton associated protein 4 DPP7 protein DSC1 protein DSN1 component of MIS12 kinetochore complex Dedicator of cytokinesis 2 Delta-aminolevulinic acid dehydratase Deoxyribonuclease Deoxyribose-phosphate aldolase Desmoglein 1 Desmoplakin Diaphanous related formin 1 Dipeptidyl peptidase 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ heat shock protein family (Hsp40) member C13 DnaJ homolog subfamily C member 3 DnaJ homolog subfamily C member 5 Docking protein 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Dynein cytoplasmic 1 heavy chain 1 Dynein light chain 1, cytoplasmic Dynein light chain Tctex-type 1 Dynein light intermediate chain E3 ubiquitin-protein ligase KCMF1 Elastase, neutrophil expressed Elongation factor 1-alpha 1 Elongation factor 2 Endoplasmic reticulum resident protein 44 FAS-associated factor 2 FERM and PDZ domain containing 3 Fatty acid-binding protein 5 Fc alpha receptor Fc fragment of IgG receptor IIb Ferritin heavy chain Ferritin light chain Fibroleukin Ficolin-2 Folate receptor 2 (Fetal) Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase G-protein coupled receptor 84 GH3 domain containing GLI pathogenesis-related 1 GTPase NRas Galectin Gamma-glutamyl hydrolase Ganglioside GM2 activator Gasdermin D Gelsolin Glia maturation factor gamma Glucose-6-phosphate isomerase Glutaminyl-peptide cyclotransferase Glutathione S-transferase Glutathione S-transferase Glycogen debranching enzyme Glycogen phosphorylase, liver form Golgin subfamily A member 7 Grancalcin Granulin Growth-regulated protein homolog gamma HECT-type E3 ubiquitin transferase Heat shock 70 kDa protein 1A Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock protein family A (Hsp70) member 6 Heme binding protein 2 Hemoglobin subunit beta Heparan-alpha-glucosaminide N-acetyltransferase Heparanase High affinity immunoglobulin epsilon receptor subunit gamma High mobility group protein B1 IQ motif containing GTPase activating protein 1 IQ motif containing GTPase activating protein 2 IST1 homolog Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin domain-containing protein Immunoglobulin subtype domain-containing protein Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Insulin like growth factor 2 receptor Integrin alpha-L Integrin beta-2 Integrin subunit alpha M Integrin subunit alpha V Interleukin enhancer binding factor 2 Isocitrate dehydrogenase [NADP] Junction plakoglobin Karyopherin subunit beta 1 Keratin, type II cytoskeletal 1 Lactotransferrin Leucine rich alpha-2-glycoprotein 1 Leukocyte elastase inhibitor Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 Leukocyte surface antigen CD47 Leukocyte surface antigen CD53 Leukotriene A-4 hydrolase Lipocalin 2 Long-chain-fatty-acid--CoA ligase Low affinity immunoglobulin gamma Fc region receptor III-A Lysophosphatidylcholine acyltransferase 1 Lysosomal alpha-glucosidase Lysosomal alpha-mannosidase Lysosomal associated membrane protein 2 Lysosome-associated membrane glycoprotein 1 Lysozyme C-1 Lysozyme C-2 Lysozyme C-3 MGC140461 protein MLEC protein MPO protein Macrophage migration inhibitory factor Magnesium transporter protein 1 Major vault protein Maltase-glucoamylase 2 (putative) Mast cell expressed membrane protein 1 Matrix metallopeptidase 25 Matrix metallopeptidase 8 Matrix metalloproteinase-9 Membrane protein BRI3 Membrane spanning 4-domains A3 Membrane-associated progesterone receptor component 1 Metalloproteinase inhibitor 2 Methyltransferase type 11 domain-containing protein Microsomal glutathione S-transferase 1 Mitogen-activated protein kinase 1 Monocyte differentiation antigen CD14 Motile sperm domain containing 2 N-acetylgalactosamine-6-sulfatase N-acetylglucosamine-6-sulfatase NADH dehydrogenase [ubiquinone] 1 subunit C2 NADH-cytochrome b5 reductase 3 NCK associated protein 1 like NFAT activating protein with ITAM motif 1 NHL repeat containing 3 NPC intracellular cholesterol transporter 2 Natural resistance-associated macrophage protein 1 Neprilysin Neurofascin Neuronal acetylcholine receptor subunit beta-4 Nicastrin Nuclear factor NF-kappa-B p105 subunit Nucleoside diphosphate kinase B O-acyltransferase ORM1-like protein 3 Olfactomedin 4 Omega-amidase NIT2 Osteoclast associated Ig-like receptor Osteoclast-stimulating factor 1 Oxidized low-density lipoprotein receptor 1 P2X purinoceptor PDGFA associated protein 1 PP1201 protein PYD and CARD domain containing Pantetheinase Pentraxin 3 Peptidase S1 domain-containing protein Peptidoglycan recognition protein 1 Peptidyl-prolyl cis-trans isomerase A Peroxiredoxin-6 Phosphoglucomutase 2 Phosphoglycerate mutase 1 Phospholipase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Placenta-specific gene 8 protein Plakophilin 1 Platelet and endothelial cell adhesion molecule 1 Platelet glycoprotein 4 Platelet-activating factor acetylhydrolase IB subunit alpha2 Platelet-activating factor receptor Pleckstrin homology domain containing O2 Polymeric immunoglobulin receptor Presenilin-1 Pro-cathepsin H Proliferation-associated 2G4 Prolylcarboxypeptidase Prosaposin Prostaglandin E synthase 2 Prostatic acid phosphatase Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome subunit alpha type-2 Proteasome subunit alpha type-5 Proteasome subunit beta Proteasome subunit beta Protein S100-A12 Protein S100-A7 Protein S100-A8 Protein S100-A9 Protein S100 Protein S100 Protein kinase C delta type Protein tyrosine phosphatase receptor type N2 Protein yippee-like 5 Protein-arginine deiminase Proteinase 3 Purine nucleoside phosphorylase Pyridoxal kinase Pyruvate kinase RAB31, member RAS onco family RAB37, member RAS onco family RAB44, member RAS onco family RAB6A, member RAS onco family RAB9B, member RAS onco family RNA helicase Rab GDP dissociation inhibitor Rab GDP dissociation inhibitor Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ras homolog family member G Ras-related protein Rab-10 Ras-related protein Rab-14 Ras-related protein Rab-18 Ras-related protein Rab-27A Ras-related protein Rab-3A Ras-related protein Rab-4 Ras-related protein Rap-1A Ras-related protein Rap-1b Ras-related protein Rap-2 Ras-related protein Rap-2c Renin receptor Resistin Rho GTPase activating protein 45 Rho GTPase activating protein 9 Rho-associated protein kinase Rho-related GTP-binding protein RhoF Ribonuclease A family member 2 Ribonuclease A-domain domain-containing protein Ribonuclease T2 STOM protein Secretory carrier-associated membrane protein Secretory leukocyte peptidase inhibitor Serine/threonine-protein kinase 11-interacting protein Serine/threonine-protein phosphatase CPPED1 Serpin B10 Serpin B6 Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin family B member 12 Serpin family B member 4 Sialidase-1 Signal recognition particle 14 kDa protein Signal regulatory protein alpha Signal-regulatory protein beta 1 Signal-regulatory protein beta 1 Small VCP/p97-interacting protein Solute carrier family 15 member 4 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 5 Solute carrier organic anion transporter family member Sorbin and SH3 domain containing 2 Spectrin alpha, non-erythrocytic 1 Sphingolipid delta(4)-desaturase DES1 Starch binding domain 1 Stimulator of interferon genes protein Surfeit locus protein 4 Synaptogyrin Synaptosomal-associated protein 25 Synaptosomal-associated protein 29 Synaptosomal-associated protein Syndecan binding protein T-complex protein 1 subunit beta T-complex protein 1 subunit theta TIR domain-containing adapter molecule 2 TNF alpha induced protein 6 TNF receptor superfamily member 1B Target of myb1 membrane trafficking protein Thioredoxin domain containing 5 Tissue alpha-L-fucosidase Toll-interacting protein Toll-like receptor 2 Trafficking protein particle complex subunit 1 Transcobalamin 1 Transforming protein RhoA Transitional endoplasmic reticulum ATPase Transmembrane protein 179B Transthyretin Tubulin beta-4B chain Tubulin beta-5 chain Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Ubiquitin protein ligase E3 component n-recognin 4 Ubiquitin-like modifier-activating enzyme ATG7 Unc-13 homolog D Uncharacterized protein Uncharacterized protein Uncharacterized protein Urokinase plasminogen activator surface receptor Urokinase-type plasminogen activator V-type proton ATPase proteolipid subunit V-type proton ATPase subunit a V-type proton ATPase subunit a VWFA domain-containing protein Vesicle amine transport 1 Vesicle-associated membrane protein 8 Vesicle-associated membrane protein-associated protein A Vinculin Voltage-gated hydrogen channel 1 Voltage-gated potassium channel subunit beta-2 X-ray repair cross complementing 5 X-ray repair cross complementing 6 adenosine deaminase glycogenin glucosyltransferase heme oxygenase (biliverdin-producing) hexokinase mitogen-activated protein kinase peptidylprolyl isomerase protein-tyrosine-phosphatase protein-tyrosine-phosphatase small monomeric GTPase thioredoxin-dependent peroxiredoxin trypsin	A0A140T831 A0A140T891 A0A140T8A5 A0A140T8C6 A0A3Q1LFK5 A0A3Q1LGT8 A0A3Q1LIW8 A0A3Q1LMG1 A0A3Q1LMV5 A0A3Q1LMW6 A0A3Q1LMZ3 A0A3Q1LNC8 A0A3Q1LNV7 A0A3Q1LPG3 A0A3Q1LPS7 A0A3Q1LQ26 A0A3Q1LQX2 A0A3Q1LR63 A0A3Q1LRA9 A0A3Q1LRK4 A0A3Q1LRW6 A0A3Q1LTS9 A0A3Q1LTT9 A0A3Q1LUD9 A0A3Q1LUG9 A0A3Q1LWA7 A0A3Q1LWC4 A0A3Q1LWX5 A0A3Q1LX90 A0A3Q1LXA9 A0A3Q1LY36 A0A3Q1LYV0 A0A3Q1LZT3 A0A3Q1M0A2 A0A3Q1M0R0 A0A3Q1M288 A0A3Q1M2J3 A0A3Q1M2M7 A0A3Q1M2R9 A0A3Q1M411 A0A3Q1M4C7 A0A3Q1M4G7 A0A3Q1M4J0 A0A3Q1M6K1 A0A3Q1M6L1 A0A3Q1M739 A0A3Q1M7I8 A0A3Q1M7Z2 A0A3Q1MAL1 A0A3Q1MAZ1 A0A3Q1MBS7 A0A3Q1MCZ8 A0A3Q1MD45 A0A3Q1MD51 A0A3Q1MDC6 A0A3Q1MFP5 A0A3Q1MFX6 A0A3Q1MHJ9 A0A3Q1MHN9 A0A3Q1MIE9 A0A3Q1MKV8 A0A3Q1ML33 A0A3Q1MNB1 A0A3Q1MPF1 A0A3Q1MPJ7 A0A3Q1MQ27 A0A3Q1MRR6 A0A3Q1MS24 A0A3Q1MS42 A0A3Q1MU65 A0A3Q1MUK3 A0A3Q1MX09 A0A3Q1MXS2 A0A3Q1N0X5 A0A3Q1N1V7 A0A3Q1N4Z1 A0A3Q1N8P4 A0A3Q1NDL5 A0A3Q1NDQ7 A0A3Q1NE02 A0A3Q1NEU9 A0A3Q1NF89 A0A3Q1NHB1 A0A3Q1NLJ5 A0A3Q1NMT9 A0A3S5ZPB0 A0A3S5ZPJ9 A0A452DHY4 A0A452DI43 A0A452DIB1 A0A452DIE3 A0A452DJ01 A0A452DJ67 A0A452DJ87 A0A452DJA8 A0JN39 A0JNA3 A1A4J1 A1L4Z7 A2VDL2 A2VDP5 A3KMY8 A4FUG5 A4IF76 A4IFE3 A4IFF5 A4IFQ6 A4IFU2 A5D7H3 A5D7R9 A5D984 A5PJK0 A5PJY9 A5PKG9 A6BMK7 A6H730 A6H797 A6QLB1 A6QLB7 A6QLS9 A6QLZ0 A6QLZ3 A6QLZ7 A6QNL0 A6QNX2 A6QPT4 A6QQ81 A6QQL0 A6QQL9 A6QR67 A7MB62 A7MBA2 A7MBA7 A7MBJ5 A7YWC4 A7YWG4 A7YWU9 A7YY49 A8E4P3 E1B6Z4 E1B6Z6 E1B725 E1B876 E1B8B5 E1B8E5 E1B8Y2 E1BA23 E1BAD2 E1BAJ4 E1BB52 E1BCC1 E1BCF4 E1BCU6 E1BD53 E1BDF5 E1BER4 E1BF48 E1BFE2 E1BFM6 E1BFP1 E1BFU3 E1BFV0 E1BGJ5 E1BHT5 E1BHY6 E1BI28 E1BI37 E1BI70 E1BIP1 E1BK38 E1BKA1 E1BKT9 E1BN47 E1BNL9 E1BNM1 E1BNY9 E1BPI3 E1BPL8 F1MAU4 F1MBI1 F1MC48 F1MC93 F1MCK4 F1MDR7 F1ME65 F1MF50 F1MGC2 F1MGY9 F1MHH9 F1MHS5 F1MHT1 F1MIC5 F1MIE6 F1MIW3 F1MIW8 F1MJ59 F1MJ63 F1MJS9 F1MKW9 F1ML17 F1ML95 F1MLP3 F1MMD5 F1MMR6 F1MMS7 F1MMX5 F1MN89 F1MNI4 F1MNN6 F1MNS8 F1MQ78 F1MQF6 F1MQT9 F1MQX9 F1MR22 F1MRG6 F1MRP0 F1MST2 F1MTK4 F1MTR1 F1MTY9 F1MU24 F1MU84 F1MUK6 F1MUP9 F1MVJ8 F1MW13 F1MW32 F1MWE0 F1MWM6 F1MWU9 F1MX50 F1MXE4 F1MXJ5 F1MXY2 F1MXZ0 F1MZ44 F1MZQ5 F1MZS9 F1N036 F1N048 F1N0T3 F1N144 F1N1F5 F1N1G1 F1N1I6 F1N3R7 F1N3T5 F1N430 F1N455 F1N4H1 F1N4Y5 F1N5H2 F1N632 F1N680 F1N720 F1N789 F1N7H2 F1N7I6 F2Z4E7 F6PZJ9 F6QEU6 F6QH17 F6QIT9 F6RMV5 G3MWP1 G3MXC8 G3MXK8 G3MXU0 G3MY77 G3MYD9 G3MZR7 G3N0J0 G3N0V2 G3N156 G3N2H4 G3N3S2 G3X6D0 G3X6Q8 G3X757 G3X7D2 G3X8C3 G5E538 G5E574 G5E589 G5E5M5 G5E5N4 G5E5S0 G5E631 G5E6Q0 H7BWW2 O46375 O46414 O46415 O46521 O46522 O46675 O77834 P00432 P01035 P01888 P02070 P04272 P05689 P07514 P07688 P08037 P10103 P11023 P12763 P17453 P19120 P24627 P25326 P26201 P28782 P32592 P33046 P34955 P46196 P52176 P55052 P56701 P58353 P61223 P61285 P61585 P61625 P62833 P62935 P67868 P68103 P68401 P79105 P79107 P79345 P80177 P80227 P81134 Q02827 Q05204 Q05588 Q05589 Q06283 Q06284 Q06285 Q08DB4 Q08DC2 Q08DD1 Q08DI5 Q0II59 Q0II86 Q0P598 Q0VCB4 Q0VCK5 Q0VCM4 Q0VCN9 Q0VCY1 Q0VD15 Q10741 Q17QB3 Q17QI1 Q17QL5 Q17QP9 Q17QQ1 Q17QQ3 Q1JPA0 Q1JPB0 Q1RMI2 Q1RMS1 Q27955 Q27975 Q28050 Q29451 Q29455 Q29RI6 Q29RY7 Q2HJ57 Q2HJD0 Q2KI42 Q2KI54 Q2KI97 Q2KI99 Q2KII9 Q2KIM0 Q2KIW2 Q2KJ25 Q2KJ46 Q2KJ64 Q2KJ81 Q2KJD0 Q2KJF1 Q2LGB5 Q2LGB7 Q2T9M8 Q2UVX4 Q32L83 Q32LK2 Q32PA1 Q32PF2 Q3LUH2 Q3MHI9 Q3MHM5 Q3MHQ1 Q3SWY3 Q3SYU2 Q3SYU6 Q3SZ62 Q3SZA1 Q3SZH7 Q3T0A3 Q3T0D2 Q3T0D8 Q3T0I2 Q3T0L2 Q3T0Q4 Q3T0Q9 Q3T0V9 Q3T0Y5 Q3T0Y8 Q3T132 Q3ZBD0 Q3ZBD2 Q3ZBD7 Q3ZBE7 Q3ZBG1 Q3ZBH0 Q3ZBH5 Q3ZBY7 Q3ZC41 Q3ZCB2 Q3ZCI9 Q3ZCL0 Q56JZ9 Q58DK5 Q58DM3 Q5E964 Q5E987 Q5E9F9 Q5EA55 Q5GN72 Q5I2E5 Q5W1C4 Q673L2 Q6QRN7 Q762I5 Q76LV1 Q76LV2 Q8MJ50 Q8SPJ1 Q8SPP7 Q9BDR7 Q9MYM4 Q9TTY5 Q9XSK2 Q9XT97	A1BG ABCA13 ABP1 ACAA1 ACLY ACP3 ACPP ACTR10 ACTR1B ACTR2 ADA2 ADAM10 ADGRE3 ADGRE5 ADGRG3 AGA AGL AGP AGPAT2 AHSG ALAD ALDH3B1 ALDOA ALDOC ALOX5 AMPD3 ANO6 ANX2 ANXA2 AOC1 AOP2 AP1M1 AP2A2 APAF1 APEH APRT ARG1 ARHA ARHGAP45 ARHGAP9 ARL8A ARMC8 ARP10 ARP2 ARPC5 ARSA ARSB ASAH1 ATAD3 ATG7 ATP11A ATP11B ATP6AP2 ATP6IP2 ATP6V0A1 ATP6V0C ATP8A1 ATP8B4 AZU1 B2M B4GALT1 BIN2 BOLA BOLA-NC1 BPI BRI3 BST1 C3 C3AR1 C5AR1 C7H1orf35 CAAF1 CAAF2 CAB39 CALML5 CAND1 CANT1 CAP1 CAPN1 CAT CATHL4 CCT2 CCT8 CD14 CD177 CD18 CD36 CD44 CD47 CD53 CD55 CD58 CD59 CD63 CD68 CD93 CDC2L CDC2L5 CDK13 CEACAM1 CEP290 CFD CFP CHI3L1 CHRNB4 CK2N CKAP4 CLEC4D CLEC5A CLEC6A CMTM6 CNN2 COMMD3 COMMD9 COPB1 COTL1 CPNE1 CPNE3 CPPED1 CRACR2A CREG1 CRISP2 CRISP3 CRISPLD2 CSNK2B CST3 CSTB CTL2 CTSA CTSB CTSC CTSD CTSH CTSS CTSZ CXCR1 CXCR2 CYB5R3 CYBA CYBB CYFIP1 CYSTM1 DDOST DDX3X DECTIN2 DEGS1 DERA DES1 DGAT1 DIA1 DIAPH1 DNAJC13 DNAJC3 DNAJC5 DNASE1L1 DNCL1 DOCK2 DOK3 DPP7 DSC1 DSG1 DSN1 DSP DYNC1H1 DYNC1LI1 DYNLL1 EEF1A EEF1A1 EEF2 EF1A ELANE ENPP4 ERK2 ERP44 FABP5 FAF2 FCAR FCER1G FCGR2B FCGR3 FCGR3A FCGRIII FCN2 FETUA FGL2 FGR FOLR2 FRK FRMPD3 FTH FTH1 FTL FUCA1 FUCA2 GAA GALNS GALT GCA GDI2 GGH GGTB2 GHDC GLA GLB1 GLIPR1 GLUT5 GM2A GMFG GNS GOLGA7 GPI GPR84 GPX GRN GSDMD GSN GSTP1 GUSB GYG1 HBB HEBP2 HEXB HGSNAT HK3 HMG1 HMGB1 HMOX2 HPSE HSC70 HSP70-1 HSP90A HSP90AA1 HSP90AB1 HSPA1A HSPA6 HSPA8 HSPC3 HSPCA HSPCB HUWE1 HVCN1 IDH1 IGF2R ILF2 IMPDH1 IMPDH2 IQGAP1 IQGAP2 IST1 ITGAL ITGAM ITGAV ITGAX ITGB2 JUP KCMF1 KCNAB2 KPNB1 KRT1 KVB2 LAMP1 LAMP2 LAMTOR1 LAMTOR2 LAMTOR3 LCN2 LGALS3 LILRA4 LOC100138951 LOC100336589 LOC100336941 LOC101904667 LOC107131803 LOC112441494 LOC112448555 LOC509956 LOC511695 LOC519132 LOC522479 LOC526163 LOC614923 LOC617406 LOC618268 LOC618463 LOC618737 LOC781990 LOC786350 LOC786410 LOC789748 LPCAT1 LRG1 LTA4H LTF LYZ1 LYZ2 LYZ3 MADM MAGT1 MAN2B1 MANB MANBA MAPK1 MAPK14 MCEMP1 MGAM2 MGC140461 MGST1 MIF MLEC MME MMP25 MMP8 MMP9 MOSPD2 MPO MS4A3 MVP NCKAP1L NCSTN NDUFC2 NEU1 NFAM1 NFASC NFKB1 NHLRC3 NIT2 NME2 NPC2 NRAS OLFM4 OLR1 ORM1 ORMDL3 OSCAR OSTF1 P2RX1 PA2G4 PADI2 PAFAH1B2P68402 PAFAHB PAFR PAS4 PDAP1 PDXK PECAM1 PFKL PGAM1 PGLYRP PGLYRP1 PGM2 PGRMC1 PGRP PHGPX PHT1 PI PIGR PKM PKM2 PKP1 PLAC8 PLAU PLAUR PLD1 PLEKHO2 PNP PPIA PRCP PRDX4 PRDX6 PRKCD PRKM1 PRSS2 PRTN3 PSAP PSEN1 PSMA2 PSMA5 PSMB1 PSMB7 PSMC2 PSMC3 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PTAFR PTGES2 PTPN6 PTPRB PTPRC PTPRJ PTPRN2 PTX3 PYCARD PYGB PYGL QPCT RAB10 RAB14 RAB18 RAB27A RAB31 RAB37 RAB3A RAB44 RAB4B RAB5B RAB6A RAB9B RAP1A RAP1B RAP2B RAP2C RECS1 RETN RHO12 RHOA RHOF RHOG RNASE2 RNASET2 ROCK1 RSTN S100A12 S100A7 S100A8 S100A9 SCAMP1 SDCBP SERPINA1 SERPINB1 SERPINB10 SERPINB12 SIRPA SIRPB1 SLC11A1 SLC15A4 SLC27A2 SLC2A3 SLC2A5 SLC44A2 SLCO4C1 SLPI SNAP23 SNAP25 SNAP29 SORBS2 SPTAN1 SRP14 STBD1 STING STING1 STK11IP STOM SURF4 SVIP SYNGR1 TCIRG1 TCN1 TICAM2 TIMP2 TLR2 TMBIM1 TMEM173 TMEM179B TMEM30A TNFAIP6 TNFRSF1B TOLLIP TOM1 TRAM TRAP2 TRAPPC1 TTR TUBB2C TUBB4B TUBB5 TXNDC4 TXNDC5 UBR4 UBXD8 UNC13D VAMP8 VAPA VAT1 VCL VCP VNN1 XRCC5 XRCC6 YPEL5 agp tsg-6	Bos taurus (cattle)
COPI-independent Golgi-to-ER retrograde traffic	1-acylglycerol-3-phosphate O-acyltransferase 3 Actin-related protein 10 Alpha-centractin BICD cargo adaptor 1 BICD cargo adaptor 2 Cytoplasmic dynein 1 intermediate chain 1 Cytosolic phospholipase A2 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein cytoplasmic 1 heavy chain 1 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light intermediate chain Dynein light intermediate chain F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha Platelet-activating factor acetylhydrolase IB subunit alpha1 Platelet-activating factor acetylhydrolase IB subunit alpha2 Platelet-activating factor acetylhydrolase IB subunit alpha Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase RAB3 GTPase activating non-catalytic protein subunit 2 RAB6A, member RAS onco family RAB6B, member RAS onco family Rab3 GTPase-activating protein catalytic subunit Ras-related protein Rab-18 phospholipase A2	A0A3Q1M3Y3 A0A3Q1M986 A0A3Q1MBS7 A0A3Q1MUW5 A0A3Q1NEU9 A0A452DHU1 A0A452DIB1 A4FUA8 A4FUE5 A4IFJ5 A5D7P3 E1BB89 E1BBI8 F1MBQ0 F2Z4F0 G3N061 G3N3P0 G5E5P6 G5E601 P61285 P68401 Q07537 Q0P5A1 Q148G7 Q29460 Q29RQ3 Q2KII9 Q32KS3 Q3MHR3 Q3ZBD2 Q3ZCF0 Q5E997	ACTR10 ACTR1A AGPAT3 ARP10 BICD1 BICD2 CAPZA1 CAPZA2 CAPZA3 CPLA2 DCTN1 DCTN2 DCTN3 DCTN4 DCTN5 DCTN6 DNCL1 DYNC1H1 DYNC1I1 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 GALNT1 GALNT2 LIS1 PAFAH1B1 PAFAH1B2P68402 PAFAH1B3 PAFAHB PAFAHG PLA2G4 PLA2G4A PLA2G6 RAB18 RAB3GAP1 RAB3GAP2 RAB6A RAB6B	Bos taurus (cattle)
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Calmodulin-like EF-hand domain-containing protein Inositol polyphosphate-5-phosphatase J Inositol-tetrakisphosphate 1-kinase Kinase Kinase Kinase Phosphatase and tensin homolog Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phospholipase C epsilon 1 Phospholipase D family member 4 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase	A0A3Q1LJT8 A0A3Q1LJY0 A0A3Q1LNH2 A0A3Q1MMD9 A0A3Q1MR28 A4FV33 E1BB73 E1BBJ7 E1BJE0 E1BLB5 F1MBY5 F1MDX9 F1MLH6 F1MN32 F1MSD7 F1MTE8 F1MYF9 G3N3D6 P0C0T1 P10894 P10895 Q1RML2	CALM INPP5B INPP5D INPP5J INPPL1 ITPK1 ITPKA ITPKB ITPKC OCRL PLCB1 PLCB4 PLCD1 PLCD3 PLCE1 PLCG1 PLCG2 PLCH1 PLCZ PLCZ1 PLD4 PTEN	Bos taurus (cattle)
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Amyloid-beta A4 protein Angiotensinogen Annexin Appetite-regulating hormone Arginine vasopressin B1 bradykinin receptor Beta-adrenergic receptor kinase 1 Bombesin receptor subtype-3 C motif chemokine ligand 1 CYSLTR2 protein Chemokine interleukin-8-like domain-containing protein Chemokine interleukin-8-like domain-containing protein Cholecystokinin Coagulation factor II (Thrombin) receptor-like 2 Cysteinyl leukotriene receptor 1 Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Extracellular calcium-sensing receptor F2R like thrombin or trypsin receptor 3 F2R like trypsin receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 3 Free fatty acid receptor 4 G protein subunit beta 3 G protein subunit gamma 13 G protein-coupled receptor 132 G protein-coupled receptor 143 G protein-coupled receptor 17 G protein-coupled receptor 39 G protein-coupled receptor 65 G-protein coupled receptor 4 GNB4 protein Gastrin releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Gastrin Glucagon receptor Glutamate metabotropic receptor 1 Glutamate metabotropic receptor 5 Gonadotropin releasing hormone 2 Gonadotropin-releasing hormone receptor Growth hormone secretagogue receptor type 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma KISS1 receptor KiSS-1 metastasis suppressor Kininogen 1 LPAR4 protein Leukotriene B4 receptor 1 Leukotriene B4 receptor 2 Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 5 Lysophosphatidic acid receptor 6 Melanin concentrating hormone receptor 2 Melanin-concentrating hormone receptor 1 Melanopsin Motilin receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Neuromedin B receptor Neuromedin S Neuromedin U receptor 1 Neuromedin U receptor 2 Neuromedin-K receptor Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Neuropeptide S receptor 1 Neuropeptide S Neurotensin receptor 1 Neurotensin receptor 2 Neurotensin/neuromedin N Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Ovarian cancer G-protein coupled receptor 1 Oxytocin receptor Oxytocin-neurophysin 1 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y receptor family member 10 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 Platelet-activating factor receptor Pro-FMRFamide-related neuropeptide FF Pro-MCH Pro-glucagon Pro-thyrotropin-releasing hormone Progonadoliberin Prokineticin 1 Prokineticin 2 Prokineticin receptor 2 Promotilin Prostaglandin E receptor 1 Prostaglandin F2-alpha receptor Protachykinin-1 Proteinase-activated receptor 1 Prothrombin Purinergic receptor P2Y11 Pyrimidinergic receptor P2Y6 Pyroglutamylated RFamide peptide receptor Pyroglutamylated RFamide peptide RGS17 protein Regulator of G protein signaling 13 Regulator of G protein signaling 18 Regulator of G protein signaling 21 Regulator of G protein signaling like 1 Regulator of G-protein signaling 16 Regulator of G-protein signaling 19 Regulator of G-protein signaling 1 Regulator of G-protein signaling 2 Regulator of G-protein signaling 4 Regulator of G-protein signaling 5 Rho guanine nucleotide exchange factor 25 Substance-K receptor Substance-P receptor Tachykinin-3 Thromboxane A2 receptor Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Tyrosine-protein kinase Uncharacterized protein Urotensin 2B Urotensin-2 Vasopressin V1a receptor Vasopressin V1b receptor X-C motif chemokine receptor 1 non-specific serine/threonine protein kinase	A0A140T858 A0A140T8B9 A0A140T8C8 A0A3Q1LTV3 A0A3Q1LUG2 A0A3Q1LXY0 A0A3Q1LYG0 A0A3Q1M7J7 A0A3Q1M9C6 A0A3Q1MAT2 A0A3Q1MSN3 A0A3Q1MXN7 A0A3Q1MXY0 A0A3Q1N2W6 A0A3Q1N6F4 A0A3Q1NGS8 A0A3S5ZPL0 A0A452DI66 A0A452DI80 A0A452DII4 A0A452DIJ2 A0A452DKE4 A1Z2Z3 A2VEA2 A4IFB7 A4IFL6 A4IFV1 A5PKD6 A5PKG3 A6QL49 A6QLQ7 A6QM11 A7MB13 A7MBG6 A7MBH4 B5U8Y5 B9VJV9 B9VJW0 C3W8S1 E1B7W0 E1B8Q3 E1BA29 E1BC83 E1BCZ7 E1BEK2 E1BFS5 E1BH23 E1BH62 E1BHL6 E1BJI3 E1BKB6 E1BKC0 E1BL07 E1BLD8 E1BMB5 E1BMI3 E1BMN4 F1MCC4 F1MCK3 F1MDE0 F1MDI7 F1MDQ5 F1ME85 F1MG23 F1MGA6 F1MIX5 F1MJD1 F1MJZ0 F1MLS2 F1MMX1 F1MN36 F1MPG4 F1MPN9 F1MRY8 F1MSD7 F1MTB2 F1MU50 F1MUR0 F1MUY4 F1MWG2 F1MX11 F1MXG2 F1MXG7 F1MY53 F1MYW8 F1N1Y7 F1N2D2 F1N2V3 F1N2X0 F1N3V3 F1N4J9 F1N4Y7 F1N5C5 F1N650 F1N7R3 F6PV87 F6QI78 G3MWJ9 G3N1H2 G3X6J0 G3X6Q0 G5E581 O46471 O46639 O46685 P01017 P01156 P01175 P01272 P01289 P01352 P02698 P05363 P08858 P10894 P11017 P17322 P21146 P21450 P23726 P23727 P25104 P28088 P30671 P32236 P32871 P35384 P38408 P38409 P41520 P48042 P50154 P56449 P62871 P63212 P63214 P63217 Q08DC7 Q0GBZ5 Q0VBW7 Q1JQB3 Q28024 Q29RM9 Q3SZ98 Q3T0T8 Q3T181 Q3ZC80 Q3ZC95 Q5E9F0 Q863C3 Q867A9 Q8SPN1 Q95125 Q9BDJ2 Q9BDJ6 Q9TTY5 Q9TUX7	ADRA1A ADRA1B ADRA1D ADRBK1 AGT AGTR1 ANXA1 APP ARHGEF25 AVP AVPR1A AVPR1B BDKRB2 BRS3 BTK CASR CCK CCKBR CHRM1 CHRM3 CHRM5 CYSLTR1 CYSLTR2 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 F2RL3 FFAR2 FFAR3 FFAR4 GAS GAST GCG GCGR GHRL GHSR GNA11 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 GNRH1 GNRH2 GNRHR GPR120 GPR132 GPR143 GPR17 GPR39 GPR4 GPR41 GPR43 GPR65 GPR68 GPR73L1 GPR92 GPRC2A GRK2 GRM1 GRM5 GRP GRPR HCRTR1 HCRTR2 HTR2A HTR2B KISS1 KISS1R KNG1 LOC112445811 LOC508666 LPAR1 LPAR2 LPAR3 LPAR4 LPAR5 LPAR6 LTB4R LTB4R2 MCHR1 MCHR2 MLN MLNR NKA NKNA NKNB NMBR NMS NMUR1 NMUR2 NPFF NPFFR1 NPFFR2 NPS NPSR1 NTS NTSR1 NTSR2 OPN4 OXT OXTR P2RY1 P2RY10 P2RY11 P2RY2 P2RY5 P2RY6 PAFR PCAR1 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKR2 PLCB1 PLCB4 PMCH PROK1 PROK2 PROKR2 PTAFR PTGER1 PTGFR QRFP QRFPR RGS1 RGS13 RGS16 RGS17 RGS18 RGS19 RGS2 RGS21 RGS3 RGS4 RGS5 RGSL1 SERPINA8 TAC1 TAC2 TAC2R TAC3 TACR1 TACR2 TACR3 TBXA2R TRH TRHR TRIO UTS2 UTS2B XCL1 XCL2 XCR1 mln	Bos taurus (cattle)
PLC beta mediated events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha	E1BA29 F1MSD7 F1N2V3 P10894 P38408 P38409	GNA11 GNA14 GNA15 GNAQ PLCB1 PLCB4	Bos taurus (cattle)
Ca2+ pathway	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 Calcineurin subunit B type 1 Calmodulin-like Catenin beta-1 EF-hand domain-containing protein Frizzled class receptor 3 Frizzled class receptor 5 Frizzled-2 Frizzled-6 G protein subunit beta 3 G protein subunit gamma 13 GNB4 protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Lymphoid enhancer binding factor 1 Mitogen-activated protein kinase kinase kinase 7 Mitogen-activated protein kinase Nuclear factor of activated T cells 1 Phosphodiesterase Phosphodiesterase Protein Wnt Protein Wnt Protein phosphatase 3 catalytic subunit alpha Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Serine/threonine-protein phosphatase Transcription factor 7 like 2 calcium/calmodulin-dependent protein kinase small monomeric GTPase	A0A3Q1MAN6 A0A3Q1MDX6 A0A3Q1MKC7 A0A3Q1MR28 A0A3Q1MZ99 A0A3Q1NGS8 A0A3S5ZPL0 A2VDU3 A4IFL6 A5PKD6 A6H703 E1B8Q3 E1B957 E1BDG5 E1BK80 E1BMX0 F1MGM1 F1MLH6 F1MP23 F1MYW8 F1N4C0 G3N2W8 G3XCF6 H2XJE9 P02698 P04696 P04972 P08239 P10894 P11017 P30671 P48452 P50154 P62871 P63099 P63212 P63214 P63217 Q0VCX4 Q28024 Q3SZ98 Q5E9F0	CALM CAMK2A CNA2 CNB CTNNB1 FZD2 FZD3 FZD5 FZD6 GNAO1 GNAT2 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 KRAS LEF1 MAP3K7 NFATC1 NLK PDE6A PDE6B PDE6G PDEG PLCB1 PPP3CA PPP3CB PPP3R1 TCF7L2 WNT11 WNT5A	Bos taurus (cattle)
Role of phospholipids in phagocytosis	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 5'-3' exonuclease PLD3 Fc fragment of IgG receptor IIb Fc fragment of IgG receptor Ia Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Low affinity immunoglobulin gamma Fc region receptor III-A Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phospholipase D family member 4 Phospholipase Phospholipase Phospholipid phosphatase 4 Phospholipid phosphatase 5 Protein kinase C delta type T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain Tyrosine-protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phospholipase A2	A0A3Q1LJY0 A0A3Q1LKV0 A0A3Q1LPG0 A0A3Q1M3L6 A0A3Q1MFB9 A0A3Q1MFP5 A0A3Q1MHG9 A0A3Q1MMD9 A0A3Q1MRR6 A0A3S5ZP99 E1BB89 F1MH11 F1MHH9 F1MXQ6 F1MYF9 F1MYM3 G3N0V0 G8JL01 P23726 P23727 P32871 P79107 Q0VCU4 Q2KJJ8	CD247 CD3G FCGR1A FCGR2B FCGR3 FCGR3A FCGRIII PIK3CA PIK3CB PIK3R1 PIK3R2 PLA2G6 PLCG1 PLCG2 PLD1 PLD2 PLD3 PLD4 PLPP4 PLPP5 PRKCD SYK	Bos taurus (cattle)
Generation of second messenger molecules	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma BOLA-DQA1 protein BoLA-DR-alpha CD101 molecule Cytoplasmic protein FYB protein GRB2 related adaptor protein 2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Linker for activation of T cells Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) MHC class II antigen MHC class II antigen Major histocompatibility complex, class II, DQ alpha 5 Major histocompatibility complex, class II, DY alpha Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 3 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TRAV29-1*01 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase non-specific serine/threonine protein kinase	A0A3Q1LSY0 A0A3Q1M088 A0A3Q1M0G8 A0A3Q1M3D2 A0A3Q1MMD9 A0A3Q1MT21 A0A3Q1MTF5 A6H6Y1 A6QQE7 A7YWJ7 A7Z039 E1BKA6 E1BLZ1 E1BMP9 F1MJK4 F1MJU5 F1ML60 F1MYF9 F1MZ60 F1N0X9 G3MWT2 G8JL01 Q08DS6 Q08E52 Q0VCU4 Q1LZB2 Q28072 Q28073 Q30309 Q3ZCM0 Q70IB5	BLA-DQB BOLA-DQA1 BOLA-DQA2 BOLA-DQA5 BOLA-DRA BOLA-DRB2 BOLA-DRB3 BOLA-DYA BOLA-DYB BoLA-DIB BoLA-DRA BoLA-DYB CD101 CD247 CD3D CD3E CD3G CD4 DYB FYB FYB1 GRAP2 HLA-DRA ITK LAT LCK LCP2 LOC100848815 NCK1 PAK1 PAK2 PAK3 PLCG1 PLCG2 TRAV29-1 ZAP70	Bos taurus (cattle)
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 B-cell CLL/lymphoma 10 C-type lectin domain containing 7A Caspase recruitment domain family member 9 Cell division cycle 34, ubiqiutin conjugating enzyme Cullin 1 F-box and WD repeat domain containing 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta MALT1 paracaspase Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappaB transcription factor p65 subunit Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein kinase C delta type S-phase kinase-associated protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TNF receptor-associated factor 6 Tyrosine-protein kinase Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LKU2 A0A3Q1LT51 A0A3Q1M118 A0A3Q1M7T8 A0A3Q1MMD9 A0A3Q1MRR6 A0A452DI44 A0A452DIY4 A1XG22 A2VDU3 A7MBA2 E1B7Z0 E1BD83 E1BIM8 F1MBI1 F1MBS7 F1MKW9 F1MLV1 F1MWE0 F1MXE4 F1MYD0 F1MYH8 F1N2F3 F1N4D3 F1N6Z0 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QJ6 Q17QP9 Q1RMX2 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2TA10 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCC3 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	BCL10 CARD9 CDC34 CHUK CLEC7A CUL1 FBXW11 IKBKB IKBKG IKKA MALT1 MAP3K7 NEMO NFKB1 NFKBIA PLCG2 PRKCD PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RELA RPS27A SKP1 SKP1A SRC SUG1 TAB1 TAB2 TAB3 TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBCEP1 UBCEP2 UBCH4 UBCH5B UBE2D1 UBE2D2 bIkBa	Bos taurus (cattle)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma B cell linker B-cell antigen receptor complex-associated protein alpha chain B-cell receptor CD22 CD19 molecule CD79b molecule Cytoplasmic protein Dual adaptor of phosphotyrosine and 3-phosphoinositides Growth factor receptor-bound protein 2 Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase adaptor protein 1 Proto-oncogene vav SH3 domain containing kinase binding protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Short transient receptor potential channel 1 Stromal interaction molecule 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LKV0 A0A3Q1M535 A0A3Q1M739 A0A3Q1M839 A0A3Q1MFU0 A0A3Q1MHG9 A0A3Q1MMD9 A0A3Q1N7P8 A0A3Q1NI55 A0A3Q1NIZ6 A0A3S5ZPA3 E1BE66 E1BKE7 F1MMQ7 F1MX21 F1N586 F1N7C3 G5E513 P23727 P40293 Q08DN7 Q08DV4 Q1LZB2 Q3T0F9 Q3ZC95	BLNK BTK CD19 CD22 CD79A CD79B DAPP1 GRB2 IGA ITPR1 ITPR2 ITPR3 MB-1 NCK1 PIK3AP1 PIK3CD PIK3R1 PLCG2 PTPN6 SH3KBP1 SOS1 STIM1 SYK TRPC1 VAV1	Bos taurus (cattle)
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Bactericidal permeability-increasing protein CD180 molecule Dynamin-1 Integrin beta-2 Integrin subunit alpha M Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type dynamin GTPase	A0A3Q1MIC9 A0A3Q1MMD9 A0A3Q1MZF3 A6QNL0 C4T7Z1 E1BJR7 F1MFI2 F1MNN7 G3MYD9 P17453 P32592 Q08DF4 Q2LGB7 Q6WCD5	BPI CD14 CD18 CD180 DNM1 DNM3 ITGAM ITGB2 LBP LY86 LY96 MD-2 PLCG2 PTPN4 TICAM2 TLR4 TRAM	Bos taurus (cattle)
Dectin-2 family	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma C-type lectin domain containing 10A C-type lectin domain family 4 member D C-type lectin domain family 4 member E C-type lectin domain family 6 member A High affinity immunoglobulin epsilon receptor subunit gamma Mucin 15, cell surface associated Mucin 20, cell surface associated Mucin-1 Mucin-2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase VWFD domain-containing protein	A0A3Q1M2T0 A0A3Q1M633 A0A3Q1M6U9 A0A3Q1MHG9 A0A3Q1MMD9 A0A3S5ZPG9 A0JNB0 E1BHM0 E1BJL5 F1N261 F1N4H1 G5E5A7 Q3LUH2 Q9BDR7	CLEC10A CLEC4D CLEC4E CLEC6A DECTIN2 FCER1G FYN LOC789503 LYN MUC1 MUC15 MUC2 MUC20 PLCG2 SYK	Bos taurus (cattle)
VEGFR2 mediated cell proliferation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 3-phosphoinositide-dependent protein kinase 1 GTPase NRas Protein kinase C beta type Protein kinase C delta type Protein kinase C RAS p21 protein activator 1 Sphingosine kinase 1 Tyrosine-protein kinase Vascular endothelial growth factor A Vascular endothelial growth factor receptor 2 small monomeric GTPase	A0A3Q1MRR6 A0A3Q1MSP9 A5D7R9 E1BIM8 E1BMX0 F1MQJ7 F1MWF1 F1MXZ6 F1MYF9 F1N7N8 P05126 P15691	KDR KRAS NRAS PDPK1 PLCG1 PRKCB PRKCB1 PRKCD PRKCZ RASA1 SPHK1 SRC VEGF VEGFA	Bos taurus (cattle)
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Adapter molecule crk BCAR1 scaffold protein, Cas family member CRK like proto-onco, adaptor protein Cytoplasmic protein Cytoplasmic protein GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B RAS p21 protein activator 1 Rap guanine nucleotide exchange factor 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase small monomeric GTPase	A0A140T878 A0A3Q1LXN8 A0A3Q1ME65 A0A3Q1ME99 A0A3Q1MQ07 A0A3Q1N3Z8 A5D7R9 A6H720 B1H0W5 E1BIM8 E1BMX0 E1BQ32 F1MGJ4 F1MX38 F1MYF9 F1MYM3 F1N339 F1N7C3 F1N7N8 G3N016 P23726 P23727 P32871 Q1LZB2 Q1RMW5 Q2KJ15 Q3T0F9 Q95115	BCAR1 CRK CRKL GRB2 GRB7 KRAS MGF NCK1 NCK2 NRAS PDGFA PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 PTPN11 RAPGEF1 RASA1 SOS1 SRC STAT1 STAT3 STAT5A STAT5B STAT6	Bos taurus (cattle)
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Artemin DOK4 protein Docking protein 1 Docking protein 2 Docking protein 5 Docking protein 6 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GFRA3 protein GRB2 associated binding protein 2 GRB2-associated-binding protein 1 Glial cell derived neurotrophic factor Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Insulin receptor substrate 2 Mitogen-activated protein kinase 7 Neurturin PDZ and LIM domain protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 Proto-oncogene tyrosine-protein kinase receptor Ret RAP1 GTPase activating protein SH3 and multiple ankyrin repeat domains 3 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LNN8 A0A3Q1M0Y1 A0A3Q1M864 A0A3Q1MTG9 A0A3Q1N8H3 A0A452DJE2 A4IFA9 A4IFJ7 A5PKJ4 A6QLU3 A7MBB8 E1B7I9 E1BD76 E1BE66 E1BIM8 E1BKU1 F1MDQ5 F1MJE0 F1MP52 F1MRT5 F1MS00 F1MYF9 F1MYM3 F1N339 F1N7C3 F6S0Q2 G3MZM3 G3N3X9 G3X7B4 P00517 P23726 P23727 P32871 Q0IIE2 Q0VCR5 Q1RMW5 Q3SX40 Q3T0F9	ARTN DOK1 DOK2 DOK4 DOK5 DOK6 FRS2 GAB1 GAB2 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB10 GRB2 GRB7 IRS2 MAPK7 NRTN PDLIM7 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PRKACA PRKACB PTPN11 RAP1GAP RET SHANK3 SHC1 SHC3 SOS1 SRC	Bos taurus (cattle)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q1LRU7 A0A3Q1M3Q3 A0A3Q1NAV6 A0MTF4 D8KXU9 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1MYF9 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF10 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF9 FGFA FGFR2 Fgf4 HBGF-1 PLCG1	Bos taurus (cattle)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho	A0A3Q1LUE0 A0A3Q1NAV6 A0MTF4 D8KXU9 E1BAI2 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MYF9 F1N6G8 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF10 FGF17 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF5 FGF5C FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 Fgf4 HBGF-1 KL PLCG1	Bos taurus (cattle)
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q1MPT9 A0MTF4 D8KXU9 E1BJU2 E1BP37 F1MHC6 F1MYF9 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF4 FGF4A FGF4C FGF5 FGF6A FGF8 FGF9 FGFA FGFR3 Fgf4 HBGF-1 PLCG1	Bos taurus (cattle)
Activated NTRK3 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Neurotrophin-3 Tyrosine-protein kinase receptor	F1MYF9 G3N3T6 Q08DT3	NTF3 NTRK3 PLCG1	Bos taurus (cattle)
Metabolism of folate and pterines	10-formyltetrahydrofolate dehydrogenase 10-formyltetrahydrofolate dehydrogenase 5-formyltetrahydrofolate cyclo-ligase C-1-tetrahydrofolate synthase, cytoplasmic Dihydrofolate reductase Folate receptor 2 (Fetal) Folylpolyglutamate synthase Methylenetetrahydrofolate reductase Monofunctional C1-tetrahydrofolate synthase, mitochondrial Proton-coupled folate transporter Reduced folate transporter Serine hydroxymethyltransferase, mitochondrial Serine hydroxymethyltransferase Solute carrier family 25 member 32 methenyltetrahydrofolate cyclohydrolase methenyltetrahydrofolate cyclohydrolase	A0A140T872 A0A140T896 A0A3Q1MU29 A0A3Q1NGK6 A0A452DI11 A4FUD0 E1BDG9 E1BMG9 E1BNJ2 F1MWN5 G3X7X2 Q05B81 Q0VCN9 Q0VCR7 Q1RMT3 Q3SZ20	ALDH1L1 ALDH1L2 DHFR FOLR2 FPGS HCP1 MTHFD1 MTHFD1L MTHFD2 MTHFD2L MTHFR MTHFS PCFT SHMT1 SHMT2 SLC19A1 SLC25A32 SLC46A1	Bos taurus (cattle)
Glucocorticoid biosynthesis	11-beta-hydroxysteroid dehydrogenase type 2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase Corticosteroid-binding globulin Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Steroid 21-hydroxylase steroid 11beta-monooxygenase steroid 11beta-monooxygenase steroid 11beta-monooxygenase	E1BF81 F1MG97 F1MU47 F1MWH3 F1N3U0 P00191 P01190 P05185 P14893	CBG CYP11B1 CYP17 CYP17A1 CYP21 CYP21A1 CYP21A2 HSD11B2 HSD3B LOC112449566 POMC SERPINA6	Bos taurus (cattle)
Prednisone ADME	11-beta-hydroxysteroid dehydrogenase type 2 AKR1C4 protein ATP binding cassette subfamily B member 1 Albumin Corticosteroid-binding globulin Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Dihydrodiol dehydrogenase 3 NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Prostaglandin F synthase 2 UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase	A0A140T897 A0A3Q1LWZ2 A0A3Q1LYU5 A0A3Q1LZ03 A0A3Q1M423 A0A3Q1MB23 A0A3Q1MIN6 E1BBB3 E1BF81 E1BG58 E1BJU8 E1BP71 F1MFF6 F1MNC0 F1MT58 F1N3U0 G3X6I4 M0QW04 M0QW14 M0QW25 P52897 P52898 Q29RV2 Q3T047 Q3ZBG2	ABCB1 AKR1C4 ALB CBG CYP3A28 CYP3A4 CYP3A5 CYP3A74 CYP3A76 HSD11B2 LOC100138004 LOC100138908 LOC100296421 LOC506594 LOC538060 LOC782061 LOC782884 LOC785762 SERPINA6 UGT1A6 UGT2B10	Bos taurus (cattle)
TP53 Regulates Metabolic Genes	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-3 Acetyl-CoA carboxylase kinase Cytochrome c oxidase assembly factor COX18 Cytochrome c oxidase assembly protein COX11, mitochondrial Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6C Cytochrome c oxidase subunit 7A-related protein, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8 Cytochrome c oxidase subunit NDUFA4 Cytochrome c oxidase subunit NDUFA4 Cytochrome c DNA damage-inducible transcript 4 protein Fructose-2,6-bisphosphatase TIGAR Glucose-6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glutathione reductase Leucine rich pentatricopeptide repeat containing Neutral amino acid transporter 9 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-5, mitochondrial Protein SCO1 homolog, mitochondrial Protein SCO2 homolog, mitochondrial Protein kinase AMP-activated non-catalytic subunit beta 2 Protein kinase AMP-activated non-catalytic subunit gamma 2 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras homolog, mTORC1 binding Ras-related GTP-binding protein A Ras-related GTP-binding protein Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR complex 1 SESN1 protein SURF1-like protein Serine/threonine-protein kinase mTOR Sestrin 3 Sestrin-2 TSC complex subunit 1 Target of rapamycin complex subunit LST8 Thioredoxin reductase 1, cytoplasmic Thioredoxin Translational activator of cytochrome c oxidase I Uncharacterized protein glutaminase glutaminase	A0A0N4STN2 A0A140T894 A0A3Q1LKB8 A0A3Q1LTU9 A0A3Q1LYC8 A0A3Q1M6L2 A0A3Q1MM55 A0A3Q1MMW4 A0A3Q1MQS6 A0A3Q1MSS5 A0A3Q1MVT8 A1A4J8 A3KMZ6 A6H784 A7MBI2 A7Z057 A8E4L1 E1B986 E1BFB4 E1BH77 E1BHZ6 E1BJK7 E1BKZ1 E1BPX9 F1MBG5 F1MFJ7 F1MG06 F1MM79 F1MM99 F1MQV7 F1N5P2 F2Z4I1 G5E5G3 O62768 O97680 P00423 P00426 P00430 P04038 P13182 P58108 P62261 P62894 P63103 P68509 P68530 Q01321 Q08E62 Q0VC36 Q0VD29 Q17QQ1 Q17QU5 Q1JQA7 Q1RMH3 Q2LL38 Q2M2U3 Q2NKS2 Q3SX43 Q3SZ68 Q3SZI4 Q3T061 Q3T0D8 Q3T132 Q3ZBD7 Q58CN8 Q5BIS9 Q5E947 Q6QTG5 Q6QTG9 Q9BGI1 Q9BGI3	COII COX1 COX11 COX14 COX16 COX18 COX19 COX2 COX20 COX3 COX4 COX4I1 COX5A COX6A1 COX6C COX7A2L COX7B COX7C COX7CP1 COXII CYC CYCS DDIT4 G6PD GBL GLS GLS2 GPI GSR LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LOC100296227 LOC783202 LRPPRC LST8 MLST8 MT-CO2 MTCO2 MTOR NDUFA4 PRDX1 PRDX2 PRDX5 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RHEB RPTOR RRAGA RRAGB RRAGC RRAGD SCO1 SCO2 SCOD1 SESN1 SESN2 SESN3 SFN SLC38A9 SURF1 TACO1 TIGAR TSC1 TXN TXNRD1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	Bos taurus (cattle)
HSF1 activation	14-3-3 protein epsilon Elongation factor 1-alpha 1 Heat shock factor protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Histone deacetylase 6 Prostaglandin E synthase 3 Transitional endoplasmic reticulum ATPase	A0A452DIU3 F1MQP3 G3X757 P62261 P68103 Q08DJ8 Q76LV1 Q76LV2	EEF1A EEF1A1 EF1A HDAC6 HSF1 HSP90A HSP90AA1 HSP90AB1 HSPC3 HSPCA HSPCB PTGES3 VCP YWHAE	Bos taurus (cattle)

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