GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **268** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Signaling by Insulin receptor	Insulin Tyrosine-protein kinase receptor	A0A8I3PWD4 P01321	INS INSR	Canis familiaris (dog)
Interleukin-2 signaling	Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase non-specific protein-tyrosine kinase	A0A8I3MVN6 A0A8I3N974 A0A8I3NAC6 A0A8I3NUU1 A0A8I3P3G0 A0A8I3RRY0 A0A8I3RS40 A0A8I3RVE7 A0A8I3RYS0 A0A8I3S4Z2 Q29416	IL2 IL2RA IL2RB JAK1 JAK3 LCK PTK2B SHC1 STAT5A STAT5B SYK	Canis familiaris (dog)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A8I3NI15 A0A8I3NVW9 A0A8I3PAR4 A0A8I3RQ77 A0A8I3S0I1 P33712	IGF1 IGF1R IGF2 IGFIA IRS1 IRS2 IRS4	Canis familiaris (dog)
Regulation of IFNG signaling	Fibronectin type-III domain-containing protein Interferon gamma Protein inhibitor of activated STAT 1 Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein	A0A8I3MY73 A0A8I3MZ64 A0A8I3NU62 A0A8I3NVH4 A0A8I3NZS0 A0A8I3P2U6 A0A8I3PSA1 A0A8I3QCJ0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 PIAS1 PTPN2 SOCS3 STAT1 SUMO1	Canis familiaris (dog)
IFNG signaling activates MAPKs	Fibronectin type-III domain-containing protein Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein	A0A8I3MY73 A0A8I3NVH4 A0A8I3PZA0 A0A8I3PZP0 A0A8I3QCJ0 A0A8I3RQD0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 MAPK1 MAPK3 RAF1	Canis familiaris (dog)
The NLRP3 inflammasome	Heat shock protein HSP 90-beta MEFV innate immunity regulator, pyrin NACHT, LRR and PYD domains-containing protein 3 P2X purinoceptor PYD and CARD domain containing Pannexin Proline-serine-threonine phosphatase interacting protein 1 Thioredoxin-interacting protein Thioredoxin Uncharacterized protein	A0A8I3N9V3 A0A8I3ND03 A0A8I3NKV1 A0A8I3P020 A0A8I3PDQ2 A0A8I3PGK7 A0A8I3PV78 A0A8I3RQW6 A0A8I3RXE3 A0A8I3RYZ8	HSP90AB1 MEFV NLRP3 P2RX7 PANX PANX1 PSTPIP1 PYCARD SUGT1 TXN TXNIP	Canis familiaris (dog)
Histamine receptors	Histamine H1 receptor Histamine H2 receptor Histamine receptor H3 Histamine receptor H4	A0A8I3MSX9 A0A8I3NPW0 A0A8I3P226 P17124	HRH1 HRH2 HRH3 HRH4	Canis familiaris (dog)
Drug-mediated inhibition of MET activation	Hepatocyte growth factor receptor Hepatocyte growth factor	A0A8I3NGY1 Q867B7	HGF MET	Canis familiaris (dog)
MET activates STAT3	Hepatocyte growth factor receptor Hepatocyte growth factor Signal transducer and activator of transcription	A0A8I3NGY1 A0A8I3RV66 Q867B7	HGF MET STAT3	Canis familiaris (dog)
MET interacts with TNS proteins	Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta Tensin 3 Tensin 4	A0A8I3MMP8 A0A8I3N5C8 A0A8I3NGY1 A0A8I3NIW4 Q867B7	HGF ITGB1 MET TNS3 TNS4	Canis familiaris (dog)
MET activates PTK2 signaling	Focal adhesion kinase 1 Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta Integrin subunit alpha 2 Integrin subunit alpha 3 Laminin subunit alpha 4 Multiple EGF like domains 6 Tyrosine-protein kinase	A0A8I3MC22 A0A8I3MMP8 A0A8I3NFG9 A0A8I3NGY1 A0A8I3NMY1 A0A8I3PA47 A0A8I3PGZ1 A0A8I3SBF9 Q867B7	HGF ITGA2 ITGA3 ITGB1 LAMA4 MEGF6 MET PTK2 SRC	Canis familiaris (dog)
MET Receptor Activation	HGF activator Hepatocyte growth factor receptor Hepatocyte growth factor Hepsin Serine peptidase inhibitor, Kunitz type 1 Serine peptidase inhibitor, Kunitz type 2	A0A8I3MSC1 A0A8I3MW78 A0A8I3NGY1 A0A8I3NIY8 A0A8I3S6Z5 Q867B7	HGF HGFAC HPN MET SPINT1 SPINT2	Canis familiaris (dog)
Orexin and neuropeptides FF and QRFP bind to their respective receptors	Hypocretin neuropeptide precursor Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Pyroglutamylated RFamide peptide receptor Pyroglutamylated RFamide peptide	A0A8I3PCA6 A0A8I3PCK7 A0A8I3RSX8 Q9GLF6 Q9TUP7	HCRT HCRTR1 HCRTR2 OX PPOX QRFP QRFPR	Canis familiaris (dog)
Interleukin-4 and Interleukin-13 signaling	Endoplasmin Interleukin 13 receptor subunit alpha 1 Interleukin-13 receptor subunit alpha-2 Interleukin-13 Interleukin-4 receptor subunit alpha Interleukin-4 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Suppressor of cytokine signaling 5 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A8I3MUC6 A0A8I3NVH4 A0A8I3PDX4 A0A8I3PSA1 A0A8I3RS40 A0A8I3RV66 A0A8I3RXB9 A0A8I3S4Z2 A0A8I3S6B0 A0A8I3SBB2 O77762 P41148 Q95LF0 Q9N0W9	GRP94 HSP90B1 HSPC4 IL13 IL13RA1 IL13RA2 IL4 IL4R JAK1 JAK2 JAK3 SOCS5 STAT1 STAT3 STAT6 TRA1 TYK2	Canis familiaris (dog)
Assembly and cell surface presentation of NMDA receptors	Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor Glutamate receptor Glutamate receptor Glutamate receptor	A0A8I3NNK2 A0A8I3NRD6 A0A8I3P9B8 A0A8I3RRH4 Q5R1P0 Q5R1P3	GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRIN3A NMDAR1	Canis familiaris (dog)
MET activates RAS signaling	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Mucin 20, cell surface associated RAN binding protein 10 Ran-binding protein 9 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A8I3N3U3 A0A8I3NGY1 A0A8I3NUU1 A0A8I3PS27 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3QSS9 A0A8I3S3D9 Q867B7	GRB2 HGF HRAS KRAS MET MUC20 NRAS RANBP10 RANBP9 SHC1 SOS1	Canis familiaris (dog)
Insulin receptor signalling cascade	Growth factor receptor bound protein 10 Growth factor receptor bound protein 2 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A8I3NBK6 A0A8I3NUU1 A0A8I3PT69 A0A8I3PWD4 A0A8I3S3D9 P01321	GRB10 GRB2 INS INSR SHC1 SOS1	Canis familiaris (dog)
Amine ligand-binding receptors	G protein-coupled receptor 143	A0A8I3PL97	GPR143	Canis familiaris (dog)
Signaling by ROBO receptors	Glypican-1 Slit guidance ligand 2 Slit guidance ligand 3	A0A8I3MRE2 A0A8I3NQC4 A0A8I3Q4U0	GPC1 SLIT2 SLIT3	Canis familiaris (dog)
Neurotransmitter receptors and postsynaptic signal transmission	5-hydroxytryptamine receptor 3A 5-hydroxytryptamine receptor 3B 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3E Glycine receptor alpha 1 Glycine receptor alpha 2 Glycine receptor alpha 3 Glycine receptor beta	A0A8I3MA77 A0A8I3MAG0 A0A8I3MZA4 A0A8I3NSZ3 A0A8I3P3M8 A0A8I3PQC9 A0A8I3Q2Z5 A0A8I3Q6S9 A0A8I3S5H9	GLRA1 GLRA2 GLRA3 GLRB HTR3A HTR3B HTR3C HTR3E LOC478649	Canis familiaris (dog)
Electric Transmission Across Gap Junctions	Gap junction protein Gap junction protein Gap junction protein Pannexin Pannexin	A0A8I3N0E0 A0A8I3N240 A0A8I3N9K8 A0A8I3PDQ2 A0A8I3QZQ9	GJA10 GJC1 GJD2 PANX PANX1 PANX2	Canis familiaris (dog)
Galactose catabolism	Galactokinase 1 Galactokinase Galactose-1-phosphate uridylyltransferase UDP-glucose 4-epimerase	A0A8I3P3X5 A0A8I3PNL4 A0A8I3PT77 Q9GKK4	GALE GALK1 GALT H3-3B	Canis familiaris (dog)	G93924TT
MET activates PTPN11	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein phosphatase non-receptor type	A0A8I3NGY1 A0A8I3NXI8 A0A8I3PMT9 A0A8I3PT69 Q867B7	GAB1 GRB2 HGF MET PTPN11	Canis familiaris (dog)
MET activates PI3K/AKT signaling	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Phosphatidylinositol 3-kinase regulatory subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3NGY1 A0A8I3NXI8 A0A8I3PT69 Q867B7	GAB1 GRB2 HGF MET PIK3CA PIK3R1	Canis familiaris (dog)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	protein-ribulosamine 3-kinase protein-ribulosamine 3-kinase	A0A8I3PPB5 A0A8I3S5V4	FN3K FN3KRP	Canis familiaris (dog)

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