GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **76 - 100** of **252** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Phospholipase C-mediated cascade; FGFR4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q6PBT8 Q6SJP8 Q804J6 Q90413 Q9DFC9	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf6b fgf8 fgf8a fgfr4 fj46f04 id:ibd5158 plcg1 wu:fb05c08 wu:fc89b01 wu:fj46f04 wu:fj57a05 zgc:194535	Danio rerio (zebrafish)
FGFR2c ligand binding and activation	FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q8JG38 Q9DFC9	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr2 id:ibd5158 wu:fb05c08 wu:fc89b01 zgc:194535	Danio rerio (zebrafish)
FGFRL1 modulation of FGFR1 signaling	FGF receptor-like protein 1a FGF18a Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Sprouty-related, EVH1 domain containing 1 Sprouty-related, EVH1 domain-containing protein 2	B3DGE3 O57341 P48802 Q1XG76 Q5MK87 Q5TKR8 Q5TLE2 Q6NV01 Q6NYK3 Q6SJP8 Q7SX76 Q8AY90 Q9DFC9	fb14c08 fc89b01 fgf-10 fgf-3 fgf-8 fgf10 fgf10a fgf17 fgf17b fgf18 fgf18a fgf2 fgf22 fgf23 fgf3 fgf4 fgf5 fgf8 fgf8a fgfrl1 fgfrl1a fj51c03 id:ibd5158 si:dkey-21e2.2 si:dkeyp-74c5.3 spred1 spred2 wu:fb14c08 wu:fc89b01 wu:fd11d03 wu:fj51c03 zgc:109774 zgc:64084 zgc:85707	Danio rerio (zebrafish)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Putative fibroblast growth factor 1	B3DGE3 F1RC43 O57341 P48802 Q1XG76 Q38PL0 Q5MK87 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q804J6 Q8AY90 Q90Z00 Q9DFC9	dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a fj46f04 id:ibd5158 kl plcg1 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 wu:fj46f04 wu:fj57a05 zgc:109774 zgc:194535	Danio rerio (zebrafish)
Negative regulation of FGFR1 signaling	Anosmin 1b Anosmin-1 Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Mitogen-activated protein kinase Mitogen-activated protein kinase Putative fibroblast growth factor 1	B3DGE3 F1RC43 O57341 P48802 Q1MT36 Q1XG76 Q38PL0 Q5MK87 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q7ZVK8 Q7ZW72 Q8AY90 Q90Z00 Q9DFC9 Q9IAR4	ERK1 anos1a anos1b anosmin-1a anosmin-1b dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a fi06b09 id:ibd5158 kal1.1 kal1.2 kal1a kal1b kl mapk1 mapk3 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 wu:fi06b09 wu:fl91z45 zERK1 zERK2 zgc:109774 zgc:194535	Danio rerio (zebrafish)
Downstream signaling of activated FGFR1	Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine-rich transmembrane protein 1b Fibronectin leucine-rich transmembrane protein 2 Klotho Putative fibroblast growth factor 1	B3DGE3 F1QF54 F1RC43 O57341 P48802 Q1XG76 Q38PL0 Q5MK87 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q8AY90 Q90Z00 Q9DFC9 X1WEV4	dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a flrt1b flrt2 id:ibd5158 kl si:dkey-21e2.2 si:dkey-87k14.1 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 zgc:109774 zgc:194535	Danio rerio (zebrafish)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 B3DHR9 O57341 P48802 Q1XG76 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q804J6 Q8AY90 Q8JG38 Q9DFC9	dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf7 fgf8 fgf8a fgfr2 fj46f04 id:ibd5158 plcg1 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 wu:fj46f04 wu:fj57a05 zgc:109774 zgc:194535	Danio rerio (zebrafish)
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Probable vesicular acetylcholine transporter-A Ras-related protein Rab-3 Synaptotagmin Vesicle-associated membrane protein 2	B2ZGJ1 Q08C75 Q5RGB5 Q5TZ27 Q7SZZ5	chat rab3a rab3ab si:ch211-255d18.4 slc18a3a syt1 syt1a vamp2 wu:fj41c01 wu:fj61c06 wu:fk56d05 zgc:112516 zgc:73302 zgc:92899	Danio rerio (zebrafish)
Synthesis, secretion, and deacylation of Ghrelin	Ghrelin O-acyltransferase Ghrelin Growth hormone 1 Insulin-like growth factor 1 Insulin Leptin Neuroendocrine convertase 1 Signal peptidase complex catalytic subunit SEC11 Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3	B1Q006 B6VCA1 C4WYH6 O73727 Q1JQ34 Q3ZV42 Q499B2 Q5BJI9 Q6DGR3 Q6NWJ2 Q90VV9	IGF-1 IGF-1L IGF-1a IGF-I fa97f07 gh1 ghl ghr ghre ghrl goat igf1 ins lepb mboat4 ob-b pcsk1 sec11 sec11a sec11l1 si:dkey-21o22.1 spcs1 spcs2 spcs3 wu:fa97f07 zgc:110014 zgc:85675 zgc:92805	Danio rerio (zebrafish)	G58161NS
Effects of PIP2 hydrolysis	Protein kinase C delta type Protein kinase C Protein kinase C Short transient receptor potential channel 3 Short transient receptor potential channel 6 isoform X1	B1H1I7 B8A467 F1RCY2 Q7ZUC5 U3N9R0	bZ1P14.9 fb09d10 fv43b11 prkcd prkcda prkceb prkcha si:rp71-1p14.9 trpc6 trpc6a trpc7b wu:fb09d10 wu:fv43b11 zgc:172124 zgc:56558	Danio rerio (zebrafish)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase	B0V2X9	fj20e02 man1a2 si:dkey-174k18.8 wu:fj20e02	Danio rerio (zebrafish)	G70323CJ
LDL clearance	Carboxylic ester hydrolase Low density lipoprotein receptor NPC intracellular cholesterol transporter 2 NPC intracellular cholesterol transporter 2 Neutral cholesterol ester hydrolase 1 O-acyltransferase	B0UYE4 B3DFW4 Q08BF1 Q6DKF1 Q7ZZT0 Q9DGJ3	LOC565099 cbe ces2 ces2a im:6908784 ldlr ldlra nceh1a npc2 npc2.2 si:dkey-21p1.4 si:dkey-38l12.2 soat1 zgc:153863 zgc:193713 zgc:193725 zgc:92416	Danio rerio (zebrafish)
Signaling by ALK	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma ALK and LTK ligand 1 ALK and LTK ligand 2b ALK tyrosine kinase receptor Midkine Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Pleiotrophin phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	B0S6V7 B3DHG9 E7F251 E7FAP8 F1QAD7 F8W2C9 F8W3R9 Q502U6 Q804J6 Q9DDG2	alk alkal1 alkal2b cb518 fb79b05 fj33b02 fj46f04 fj48a12 mdk mdk2 mdkb pik3ca pik3cb pik3r1 pik3r2 plcg1 plei2 ptn wu:fb65b05 wu:fb79b05 wu:fj33b02 wu:fj46f04 wu:fj48a12 wu:fj57a05 zHBNF zgc:111787	Danio rerio (zebrafish)
Signaling by LTK	ALK and LTK ligand 1 ALK and LTK ligand 2b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Tyrosine-protein kinase receptor phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	B0S6V7 B3DHG9 E7F251 E7FAP8 F1QAD7 F1QVU0 F8W2C9	alkal1 alkal2b ltk pik3ca pik3cb pik3r1 pik3r2 wu:fb65b05	Danio rerio (zebrafish)
PI-3K cascade:FGFR1	Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Klotho Phosphatidylinositol 3-kinase regulatory subunit alpha Putative fibroblast growth factor 1 phosphatidylinositol-4,5-bisphosphate 3-kinase	B0S6V7 B3DGE3 F1QAD7 F1RC43 O57341 P48802 Q1XG76 Q38PL0 Q5MK87 Q5RKN6 Q5TLE1 Q5TLE2 Q6PBT8 Q6PC73 Q6SJP8 Q8AY90 Q90Z00 Q9DFC9	dob fb18e12 fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a grb2 grb2a grb2b id:ibd5158 kl pik3ca pik3r1 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fb05c08 wu:fb18e12 wu:fb34e06 wu:fb65b05 wu:fc89b01 wu:fd11d03 zgc:103549 zgc:109774 zgc:194535 zgc:73077	Danio rerio (zebrafish)
Proton/oligopeptide cotransporters	Peptide transporter PEPT1 Solute carrier family 15 member 2	B0S6T2 Q7SYE4	PEPT1 fd47f07 slc15a1 slc15a1b slc15a2 wu:fd47f07	Danio rerio (zebrafish)
RHO GTPases Activate Formins	Actin, cytoplasmic 1 Actin, cytoplasmic 2 Disheveled-associated activator of morphogenesis 1 Dishevelled, dsh homolog 2 (Drosophila) Formin-like 1a Profilin Profilin Profilin Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoA-C SLIT-ROBO Rho GTPase-activating protein 2	B0S6J3 E7F0A1 I3ITQ8 Q5RHJ3 Q6AZA1 Q7T2E8 Q7ZSZ9 Q7ZVF9 Q7ZVI7 Q802D5 Q803Q5	actba actbb bact bactin1 bactin2 bactzf daam1b daam1l dvl2 fa91a03 fc83b10 fmnl1a hm:zeh0341 pfn1 pfn2 pfn2a pfn2b pfn2l rac1 rac1a rhoac sb:cb813 sb:eu471 si:ch211-87i20.1 srgap2 wu:fa91a03 wu:fb01g08 wu:fb02e10 wu:fb54f09 wu:fc05d12 wu:fc83b10 wu:fd16e02 wu:fd58f06 wu:fi35b08 wu:fo71e09 wu:fp54a02 zgc:55372 zgc:55823 zgc:55917 zgc:86790 zgc:86934	Danio rerio (zebrafish)
Platelet homeostasis	P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor	B0R182 Q7SZL9 Q7SZM0 Q7SZM1 Q7SZM2 Q9I8N8	P2X.514 P2X3 fb99b08 p2rx1 p2rx2 p2rx3 p2rx3a p2rx5 p2rx7 p2rx8 p2x3 p2x5 p2xr1 p2xr2 p2xr514 p2xr7 wu:fb99b08 zP2X3 zfP2X3	Danio rerio (zebrafish)
Elevation of cytosolic Ca2+ levels	P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Short transient receptor potential channel 3 Short transient receptor potential channel 6 isoform X1	B0R182 F1RCY2 Q7SZL9 Q7SZM0 Q7SZM1 Q7SZM2 Q9I8N8 U3N9R0	P2X.514 P2X3 bZ1P14.9 fb99b08 p2rx1 p2rx2 p2rx3 p2rx3a p2rx5 p2rx7 p2rx8 p2x3 p2x5 p2xr1 p2xr2 p2xr514 p2xr7 si:rp71-1p14.9 trpc6 trpc6a trpc7b wu:fb99b08 zP2X3 zfP2X3	Danio rerio (zebrafish)
Vitamin B2 (riboflavin) metabolism	Ectonucleotide pyrophosphatase/phosphodiesterase 1 FAD synthase Solute carrier family 52, riboflavin transporter, member 3-A Tartrate-resistant acid phosphatase type 5	B0JZL7 B0S5Y3 Q68EH8 Q7SXT1	TRAP acp5 acp5a enpp1 flad1 rft2a sb:cb576 si:ch211-142e24.2 slc52a3a wu:fb19f01 wu:fb30b03 wu:fi14e01 wu:fj66f03 zgc:136238 zgc:63825	Danio rerio (zebrafish)
Electric Transmission Across Gap Junctions	Gap junction protein Gap junction protein Pannexin-1 Pannexin	B0FL75 B1P2E8 Q7ZUN0 Q8JFD6	PANX connexin35 cx35 cx35b cx52.7 gja10a gja9 gjd2b panx1 panx1a panx2 si:ch211-192n14.2 zgc:194445 zgc:194451 zgc:55631	Danio rerio (zebrafish)
Nectin/Necl trans heterodimerization	Cell adhesion molecule 1b isoform 1 Nectin 1b Nectin-3-like protein	B0F6R1 B0JYH6 Q58EG3	cadm1b nectin1b nectin3 pvrl1b pvrl3l sc:d0664	Danio rerio (zebrafish)
RND2 GTPase cycle	Aldehyde dehydrogenase Arhgap1 protein BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 Caveolin Cytoskeleton-associated protein 4 Desmoglein-2.1 Family with sequence similarity 83 member B Fibroblast growth factor receptor substrate 2 Kinase D-interacting substrate of 220 kDa B Leucine-rich repeat-containing protein 1 Nuclear migration protein nudC Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Plexin D1 Protein HEG Protein scribble homolog RNA binding motif protein 39b isoform X1 RNA-binding motif protein 39a Rho GTPase-activating protein 35 Rho GTPase-activating protein 5 Rho family GTPase 2 Transferrin receptor protein 1 Vang-like protein 2 Vang-like protein receptor protein-tyrosine kinase	A9ULR9 B0S6V7 B0V210 B3DHG9 E7F020 E7F4Q7 E7F8G5 F1R372 F1R5K5 H2EQR6 Q0P4B0 Q4H4B6 Q568D8 Q58ER0 Q5BL36 Q5MPX4 Q6DSU3 Q6NW47 Q6NZS1 Q6R8J2 Q6YLH9 Q7T163 Q7ZVD2 Q803H1 Q8UVJ6 Q90ZZ8	Aldh-III CAV1 LOC100004299 Rho aldh3a2 aldh3a2a arhgap1 arhgap35a arhgap5 arhn arms cav1 ckap4 dsg2 dsg2.1 dsga epha2 epha2a fam83b fk03b12 fk61c06 frs3 heg id:ibd5152 kctd13 kidins220 kidins220b llk lrrc1 nudc pik3r1 pik3r2 plxnd1 rbm39a rbm39b rnd2 rnpc2 rnpc2l rtk6 scrb1 scrib si:dz163l24.1 stb2 stbm tfr1a tnfaip1 tri vangl1 vangl2 wu:cegs2891 wu:fa97g07 wu:fb09c08 wu:fb65b05 wu:fc06b11 wu:fc07c04 wu:fi06b02 wu:fk03b12 wu:fk61c06 zgc:101523 zgc:110361 zgc:112139 zgc:113117 zgc:153204 zgc:55302 zgc:55780 zgc:56099 zgc:77379 zgc:85670 zgc:92064	Danio rerio (zebrafish)
Opsins	Encephalopsin Melanopsin-A Opsin-1, short-wave-sensitive 1 Opsin-5 RPE-retinal G protein-coupled receptor Red-sensitive opsin-1 Red-sensitive opsin-2 Retinal pigment epithelium rhodopsin homolog/peropsin Rhodopsin	A9NJI7 E6P6L8 P35359 Q2KNE5 Q567Y2 Q66I55 Q8AYN0 Q9W6A7 Q9W6A9	Opn5m lws1 lws2 opn1lw1 opn1lw2 opn1sw1 opn1sw2 opn3 opn4 opn4a opn4d opn4m1 opn5 rdops rgr rgr1 rgra rho rrh si:ch211-105n9.2 sws1 uvops zfo2 zgc:103757 zgc:110660	Danio rerio (zebrafish)
Multifunctional anion exchangers	Chloride anion exchanger Sodium-coupled monocarboxylate transporter 2 Sodium-independent sulfate anion transporter Solute carrier family 26 member 6, like Sulfate transporter	A9JTH4 B6DUH7 E7F9I7 Q7T2A2 Q7T384	SLC26A6 si:dkey-31f5.2 slc26a11 slc26a2 slc26a3 slc26a3.1 slc26a6l slc5a12 smctn wu:fd14d06 zgc:64158	Danio rerio (zebrafish)

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