GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source Last Updated
Reactome March 20, 2024
ECODAB April 1, 2019
Displaying entries 151 - 175 of 252 in total
Pathway Name Protein Name UniProt ID Gene Symbol ▼ Organism GlyTouCan ID
Keratan sulfate degradation
  • Lum
  • fmoda
  • gnsa
  • im:6910494
  • kera
  • lum
  • ogn
  • ogna
  • si:ch211-103f16.4
  • zgc:113456
  • zgc:113545
  • zgc:114066
  • zgc:86661
Danio rerio (zebrafish)
Lysosphingolipid and LPA receptors
  • Lpar3
  • edg1
  • edg2
  • edg5
  • lpar1
  • lpar2a
  • lpar3
  • lpar5a
  • lpar6
  • lpar6l
  • p2ry5
  • s1pr1
  • s1pr2
  • s1pr5b
  • si:dz22b13.1
  • si:dz46m7.1
  • wu:fb62d01
  • zgc:101053
  • zgc:158362
  • zgc:66034
  • zgc:92157
Danio rerio (zebrafish)
Lewis blood group biosynthesis
  • LOC565422
  • LOC796410
  • LOC798349
  • b3galt10.1
  • b3galt11
  • b3galt2
  • fe05b03
  • fut10
  • fut11
  • fut7
  • fut9a
  • im:7151092
  • siat4c
  • st3gal4
  • wu:fe05b03
  • zgc:152705
  • zgc:158162
  • zgc:194168
  • zgc:194170
  • zgc:194313
  • zgc:194330
  • zgc:76904
Danio rerio (zebrafish)
LDL clearance
  • LOC565099
  • cbe
  • ces2
  • ces2a
  • im:6908784
  • ldlr
  • ldlra
  • nceh1a
  • npc2
  • npc2.2
  • si:dkey-21p1.4
  • si:dkey-38l12.2
  • soat1
  • zgc:153863
  • zgc:193713
  • zgc:193725
  • zgc:92416
Danio rerio (zebrafish)
Highly calcium permeable nicotinic acetylcholine receptors
  • LOC555747
  • LOC556619
  • chrna1
  • chrna2
  • chrna2a
  • chrna4
  • chrna4b
  • chrna6
  • chrnb3a
  • nic1
  • si:dkey-234d14.1
  • zgc:136717
Danio rerio (zebrafish)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
  • LOC555747
  • LOC556619
  • chrna1
  • chrna2
  • chrna2a
  • chrna4
  • chrna4b
  • chrna5
  • chrna6
  • chrna7
  • chrna7a
  • chrnb3a
  • dZ70B1.1
  • nic1
  • si:dkey-234d14.1
  • zgc:110642
  • zgc:136717
Danio rerio (zebrafish)
HDACs deacetylate histones
  • LOC100150038
  • LOC100329358
  • LOC100331412
  • LOC100332229
  • LOC103908680
  • LOC108181627
  • LOC562770
  • LOC570661
  • LOC794549
  • h2af1al
  • h2afx1
  • h2ax1
  • hdac10
  • hdac8
  • hist2h2l
  • si:ch211-113a14.17
  • si:ch211-113a14.29
  • si:ch211-113a14.6
  • si:ch73-36p18.4
  • si:dkey-108k21.12
  • si:dkey-108k21.18
  • si:dkey-108k21.28
  • si:dkey-23a13.7
  • zgc:112234
  • zgc:113984
  • zgc:173585
  • zgc:173587
  • zgc:194998
  • zgc:56685
Danio rerio (zebrafish)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • LOC100150038
  • LOC100329358
  • LOC100331412
  • LOC100332229
  • LOC103908680
  • LOC108181627
  • LOC562770
  • LOC570661
  • LOC794549
  • fj63d08
  • h2af1al
  • h2afvb
  • h2afvl
  • h2afx1
  • h2afza
  • h2av
  • h2ax1
  • h2az2a
  • h2az2b
  • h3-5
  • h3f3a
  • h3f3b.1
  • h3f3c
  • h3f3d
  • hist2h2l
  • im:6896397
  • prmt6
  • runx1
  • runxa
  • si:ch211-113a14.17
  • si:ch211-113a14.29
  • si:ch211-113a14.6
  • si:ch73-36p18.4
  • si:dkey-108k21.12
  • si:dkey-108k21.18
  • si:dkey-108k21.28
  • si:dkey-23a13.7
  • si:dkey-6n6.6
  • sin3aa
  • sin3b
  • wu:fj63d08
  • zgc:112234
  • zgc:113984
  • zgc:173585
  • zgc:173587
  • zgc:194998
  • zgc:56685
Danio rerio (zebrafish)
Estrogen-dependent gene expression
  • LOC100150038
  • LOC100329358
  • LOC100331412
  • LOC100332229
  • LOC103908680
  • LOC108181627
  • LOC562770
  • LOC570661
  • LOC794549
  • carm1
  • cited1
  • erbb4
  • erbb4a
  • esr
  • esr1
  • fc15h02
  • fi05d05
  • fj36b10
  • fkd7
  • forkhead-7
  • foxa1
  • gata3
  • gb:dq017620
  • gro1
  • groucho1
  • gta3
  • gtf2a1
  • gtf2a2
  • h2af1al
  • h2afvb
  • h2afvl
  • h2afx1
  • h2afza
  • h2av
  • h2ax1
  • h2az2a
  • h2az2b
  • h3-5
  • h3f3a
  • h3f3b.1
  • h3f3c
  • h3f3d
  • hist2h2l
  • im:6896397
  • jmjd2b
  • kat2b
  • kat5a
  • kdm4b
  • nr3a1
  • nrip1a
  • pg
  • pgr
  • pr
  • si:ch211-113a14.17
  • si:ch211-113a14.29
  • si:ch211-113a14.6
  • si:ch211-124a3.4
  • si:ch211-227n20.1
  • si:ch73-36p18.4
  • si:dkey-108k21.12
  • si:dkey-108k21.18
  • si:dkey-108k21.28
  • si:dkey-23a13.7
  • tbp
  • tf2a
  • tle3b
  • wu:fc15h02
  • wu:fi05d05
  • wu:fj36b10
  • zgc:112234
  • zgc:113984
  • zgc:173585
  • zgc:173587
  • zgc:194998
  • zgc:55847
  • zgc:56685
Danio rerio (zebrafish)
PRC2 methylates histones and DNA
  • LOC100150038
  • LOC100329358
  • LOC100331412
  • LOC100332229
  • LOC103908680
  • LOC108181627
  • LOC562770
  • LOC570661
  • LOC794549
  • aebp2
  • cb633
  • dnmt3b
  • dnmt3bb.1
  • dnmt4
  • eed
  • ezh2
  • h2af1al
  • h2afvb
  • h2afvl
  • h2afx1
  • h2afza
  • h2av
  • h2ax1
  • h2az2a
  • h2az2b
  • h3-5
  • h3f3a
  • h3f3b.1
  • h3f3c
  • h3f3d
  • hist2h2l
  • im:6896397
  • jarid2b
  • jmj
  • mtf2
  • rbb4
  • rbb4l
  • rbbp4
  • rbbp7
  • si:ch211-113a14.17
  • si:ch211-113a14.29
  • si:ch211-113a14.6
  • si:ch73-36p18.4
  • si:dkey-108k21.12
  • si:dkey-108k21.18
  • si:dkey-108k21.28
  • si:dkey-23a13.7
  • suz12
  • suz12b
  • wu:cegs2813
  • zgc:112234
  • zgc:113984
  • zgc:136399
  • zgc:152758
  • zgc:173585
  • zgc:173587
  • zgc:194998
  • zgc:56685
Danio rerio (zebrafish)
Condensation of Prophase Chromosomes
  • LOC100150038
  • LOC100329358
  • LOC100331412
  • LOC100332229
  • LOC103908680
  • LOC108181627
  • LOC562770
  • LOC570661
  • LOC794549
  • SMC2L1
  • cb267
  • cb525
  • cb636
  • ccnb
  • ccnb1
  • cdc2
  • cdk1
  • cycb
  • cycb1
  • fb92e05
  • h2af1al
  • h2afvb
  • h2afvl
  • h2afx1
  • h2afza
  • h2av
  • h2ax1
  • h2az2a
  • h2az2b
  • hist2h2l
  • id:ibd2253
  • ik:tdsubc_2d1
  • im:6896397
  • kmt5aa
  • ncapd3
  • ncapg2
  • ncaph2
  • phf8
  • plk
  • plk1
  • rb1
  • set8a
  • setd8
  • setd8a
  • si:ch211-113a14.17
  • si:ch211-113a14.29
  • si:ch211-113a14.6
  • si:ch73-36p18.4
  • si:dkey-108k21.12
  • si:dkey-108k21.18
  • si:dkey-108k21.28
  • si:dkey-23a13.7
  • smc2
  • wu:fa19g04
  • wu:fb16d01
  • wu:fb16e07
  • wu:fb37g11
  • wu:fb76g03
  • wu:fb92e05
  • wu:fc30e01
  • wu:fi21c01
  • xx:tdsubc_2d1
  • zeh1628
  • zgc:112234
  • zgc:154147
  • zgc:173585
  • zgc:173587
  • zgc:194998
  • zgc:55326
  • zgc:55549
  • zgc:56685
  • zgc:92032
Danio rerio (zebrafish)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • LOC100150038
  • LOC100329358
  • LOC100331412
  • LOC100332229
  • LOC103908680
  • LOC108181627
  • LOC562770
  • LOC570661
  • LOC794549
  • NR3C4
  • ar
  • grip1
  • h2af1al
  • h2afvb
  • h2afvl
  • h2afx1
  • h2afza
  • h2av
  • h2ax1
  • h2az2a
  • h2az2b
  • h3-5
  • h3f3a
  • h3f3b.1
  • h3f3c
  • h3f3d
  • hist2h2l
  • im:6896397
  • jmjd2c
  • kdm4c
  • ncoa2
  • pkn1b
  • si:ch211-113a14.17
  • si:ch211-113a14.29
  • si:ch211-113a14.6
  • si:ch73-36p18.4
  • si:dkey-108k21.12
  • si:dkey-108k21.18
  • si:dkey-108k21.28
  • si:dkey-23a13.7
  • src2
  • tif2
  • wu:fd55d07
  • zgc:112234
  • zgc:113984
  • zgc:173585
  • zgc:173587
  • zgc:194998
  • zgc:56685
Danio rerio (zebrafish)
NoRC negatively regulates rRNA expression
  • LOC100150038
  • LOC100329358
  • LOC100331412
  • LOC100332229
  • LOC103908680
  • LOC108181627
  • LOC562770
  • LOC570661
  • LOC794549
  • MBD3
  • h2af1al
  • h2afvb
  • h2afvl
  • h2afx1
  • h2afza
  • h2av
  • h2ax1
  • h2az2a
  • h2az2b
  • h3-5
  • h3f3a
  • h3f3b.1
  • h3f3c
  • h3f3d
  • hist2h2l
  • im:6896397
  • mbd1
  • mbd1b
  • mbd2
  • mbd3a
  • si:ch211-113a14.17
  • si:ch211-113a14.29
  • si:ch211-113a14.6
  • si:ch73-36p18.4
  • si:dkey-108k21.12
  • si:dkey-108k21.18
  • si:dkey-108k21.28
  • si:dkey-23a13.7
  • wu:fa97f06
  • wu:fa98f07
  • wu:fi45g12
  • zK13A21.11
  • zK13A21.17
  • zgc:111862
  • zgc:112234
  • zgc:113984
  • zgc:173585
  • zgc:173587
  • zgc:194998
  • zgc:56685
Danio rerio (zebrafish)
Platelet Adhesion to exposed collagen
  • LOC100004428
  • VWF
  • gp1bb
  • lrcc54
  • nyx
  • si:ch1073-474e24.1
  • si:dkey-285c2.8
  • tsk
  • tsku
  • vasn
  • vasnb
  • vwf
Danio rerio (zebrafish)
GP1b-IX-V activation signalling
  • LOC100004428
  • VWF
  • gp1bb
  • hm:zehn0976
  • lrcc54
  • nyx
  • pik3r1
  • si:ch1073-474e24.1
  • si:dkey-285c2.8
  • src
  • tsk
  • tsku
  • vasn
  • vasnb
  • vwf
  • wu:fb33b01
  • wu:fb65b05
  • ywhabl
  • zgc:73065
  • zgc:77351
Danio rerio (zebrafish)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • LOC100004299
  • arhgap35a
  • crk
  • dock1
  • fb34h10
  • fc05a01
  • fi19g05
  • hrasb
  • hrasl
  • nras
  • ptk6b
  • pxn
  • pxna
  • rac1
  • rac1a
  • rasa1b
  • rhoac
  • wu:fb34h10
  • wu:fc05a01
  • wu:fc54a04
  • wu:fd16e02
  • wu:fi19g05
  • wu:fw71f12
  • zgc:100936
  • zgc:110734
  • zgc:153964
  • zgc:55823
  • zgc:55917
  • zgc:86934
Danio rerio (zebrafish)
Sema4D mediated inhibition of cell attachment and migration
  • LOC100004299
  • arhgap35a
  • c-met
  • cmet
  • fb23a02
  • met
  • plxnb1b
  • rhoac
  • rnd1a
  • rnd1b
  • rnd1l
  • rras
  • wu:fb23a02
  • wu:fj98h09
  • wu:fk50c04
  • zgc:153089
  • zgc:92588
Danio rerio (zebrafish)
Phase 4 - resting membrane potential
  • KCNK18
  • TREK-2A
  • im:7150627
  • kcnj12b
  • kcnj14
  • kcnj2
  • kcnj2a
  • kcnk1
  • kcnk10a
  • kcnk13a
  • kcnk18
  • kcnk1a
  • kcnk2b
  • kcnk5a
  • si:ch211-120k19.4
  • si:dkey-121j17.4
  • si:dkey-63b1.2
  • trek-1
  • zgc:123268
  • zgc:123271
Danio rerio (zebrafish)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • JAM
  • ai39657
  • arhgef18
  • arhgef18a
  • asip
  • bazooka
  • cb537
  • cgn
  • f11r
  • f11r.1
  • hm:zeh0386
  • ik:tdsubc_1f2
  • par-3
  • par3
  • pard3
  • pard3ab
  • pard6a
  • pard6alpha
  • rhoac
  • rps27a
  • si:ch73-186j5.3
  • smurf1
  • tdsubc_1f2
  • tgfb1
  • tgfb1a
  • tgfbr1b
  • tgfbr2
  • tgfbr2b
  • uba52
  • wu:fa91f08
  • wu:fb13a07
  • wu:fb30b12
  • wu:fc07c05
  • wu:fc21e04
  • wu:fj05c10
  • wu:fj05f11
  • wwp1
  • xx:ai39657
  • xx:tdsubc_1f2
  • zgc:103642
  • zgc:110498
  • zgc:123344
  • zgc:66168
  • zgc:66401
  • zgc:85686
Danio rerio (zebrafish)
Signaling by SCF-KIT
  • JAK2bCA
  • Stat5
  • ZFMMP-9
  • fb18e12
  • fj05a08
  • fj21h04
  • fj59e07
  • fynb
  • grap
  • grap2a
  • grapa
  • grb10
  • grb10a
  • grb2
  • grb2a
  • grb2b
  • hrasb
  • hrasl
  • jak2
  • jak2b
  • kit
  • kita
  • kitla
  • kitlga
  • lck
  • mmp9
  • nras
  • pik3ca
  • pik3r1
  • pik3r2
  • pik3r3a
  • ptpru
  • rptppsi
  • sb:eu508
  • sb:eu615
  • sos1
  • sparse
  • src
  • stat1
  • stat1a
  • stat5
  • stat5.1
  • stat5.2
  • stat5a
  • stat5b
  • stat6
  • stat7
  • tec
  • wu:fb02g06
  • wu:fb07b05
  • wu:fb16a12
  • wu:fb18e12
  • wu:fb34e06
  • wu:fb65b05
  • wu:fi98c09
  • wu:fj05a08
  • wu:fj21h04
  • wu:fj59e07
  • wu:fj66g07
  • wu:fk56b03
  • yes
  • yes1
  • zgc:103549
  • zgc:110202
  • zgc:110734
  • zgc:112091
  • zgc:136695
  • zgc:158274
  • zgc:64165
  • zgc:73077
  • zgc:73230
  • zgc:91987
Danio rerio (zebrafish)
Antimicrobial peptides
  • INTL1
  • INTL2
  • INTL3
  • LOC793075
  • PGRP-SC1a
  • im:7150573
  • intl2
  • intl3
  • itln1
  • itln2
  • itln3
  • leap2
  • lys-C
  • lyz
  • nkl.4
  • nkld
  • pglyrp2
  • pglyrp5
  • pgrp-l
  • rnasel2
  • rnasel3
  • rnasel4
  • si:ch211-139g14.6
  • si:ch211-194p6.4
  • si:ch211-202c21.3
  • si:dkey-113g17.4
  • si:rp71-40n14.1
  • wu:fj22b05
  • zgc:136734
  • zgc:153267
  • zgc:194626
  • zgc:194647
Danio rerio (zebrafish)
Other interleukin signaling
  • IL-34
  • STX4A
  • csf1-2
  • csf1b
  • csf1r
  • fc21b12
  • fms
  • il34
  • im:7039434
  • si:ch211-239j19.3
  • si:dkey-220f10.3
  • stx4
  • txlna
  • wu:fc08c10
  • wu:fc21b12
  • zgc:158436
  • zgc:56272
Danio rerio (zebrafish)
Synthesis, secretion, and deacylation of Ghrelin
  • IGF-1
  • IGF-1L
  • IGF-1a
  • IGF-I
  • fa97f07
  • gh1
  • ghl
  • ghr
  • ghre
  • ghrl
  • goat
  • igf1
  • ins
  • lepb
  • mboat4
  • ob-b
  • pcsk1
  • sec11
  • sec11a
  • sec11l1
  • si:dkey-21o22.1
  • spcs1
  • spcs2
  • spcs3
  • wu:fa97f07
  • zgc:110014
  • zgc:85675
  • zgc:92805
Danio rerio (zebrafish)
Apoptotic cleavage of cellular proteins
  • IAP1
  • bcap31
  • birc2
  • birc3
  • casp10
  • casp3
  • casp3a
  • casp6
  • casp6a
  • casp7
  • casp8l2
  • fb09d10
  • fnta
  • fv43b11
  • im:6909421
  • mst4
  • prkcd
  • prkcda
  • satb1a
  • sb:cb955
  • si:bz30i22.4
  • si:ch211-195k18.2
  • si:rp71-30i22.4
  • stk24a
  • stk26
  • wu:fb09d10
  • wu:fb51d12
  • wu:fv43b11
  • wu:fz92f09
  • zgc:100890
  • zgc:110595
  • zgc:112960
  • zgc:158397
  • zgc:163071
  • zgc:175288
  • zgc:56389
  • zgc:56558
Danio rerio (zebrafish)
Heme signaling
  • HBA2r
  • HBAA1
  • LOC100334599
  • MGC173646
  • OTTDARP00000001843
  • OTTDARP00000001844
  • OTTDARP00000001846
  • OTTDARP00000002003
  • SI:dZ118J2.10
  • SI:dZ118J2.7
  • SI:dZ118J2.8
  • SI:dZ118J2.9
  • bE1
  • ba1
  • ba1l
  • be1c
  • dZ118J2.6
  • hba2
  • hbae1
  • hbae1.1
  • hbae1.2
  • hbae1.3
  • hbba2
  • hbbe1
  • hbbe1.1
  • hbbe1.2
  • hbbe1.3
  • hbbe1c
  • hbbe2
  • hbbe3
  • pcft
  • pgrmc2
  • si:busm1-118j2.5
  • si:by119c3.1
  • si:by119c3.2
  • si:by119c3.3
  • si:ch211-5k11.12
  • si:xx-119c3.3
  • slc46a1
  • wu:fa12a11
  • wu:fb25g12
  • wu:fb74f06
  • wu:fd12f11
  • zgc:110736
  • zgc:56692
  • zgc:86936
Danio rerio (zebrafish)

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024