GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **252** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
FGFR3b ligand binding and activation	FGF18a Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 3 Fibroblast growth factor Putative fibroblast growth factor 1	O57341 Q38PL0 Q5TKR8 Q6PBT8 Q6SJP8 Q9I8X3	dob fgf-1 fgf-8 fgf1 fgf17 fgf17b fgf18 fgf18a fgf20a fgf8 fgf8a fgfr3 wu:fb05c08	Danio rerio (zebrafish)
Cellular hexose transport	Facilitated glucose transporter 1 Glucose transporter 2 Sodium-dependent glucose transporter 1 Sodium/glucose cotransporter 1 Sodium/glucose cotransporter 2 Sodium/glucose cotransporter 4 Solute carrier family 2 (Facilitated glucose transporter), member 8-like Solute carrier family 2 member 3b Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 45 member 3 precursor Sugar transporter SWEET1	A4QN56 A4QP56 A8WHP3 F1R0H0 F1R1M7 Q102R8 Q285P3 Q5EB14 Q6NWD8 Q6NWE6 Q6NWF1 Q7ZWH3	fc29a02 glut1 glut10 glut12 glut1a glut1b glut2 mfsd4b naglt1 rag1ap1 sb:cb753 sb:cb808 slc2a1 slc2a10 slc2a12 slc2a1a slc2a2 slc2a3b slc2a8 slc2a8l slc45a3 slc50a1 slc5a1 slc5a2 slc5a9 wu:fb62h10 wu:fc29a02 zgc:56364 zgc:66074 zgc:85782 zgc:85792	Danio rerio (zebrafish)	G58161NS G70323CJ
Regulation of insulin secretion	Facilitated glucose transporter 1 Glucose transporter 2	Q102R8 Q285P3	fc29a02 glut1 glut1a glut1b glut2 slc2a1 slc2a1a slc2a2 wu:fb62h10 wu:fc29a02	Danio rerio (zebrafish)	G58161NS
FRS-mediated FGFR1 signaling	Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Klotho Putative fibroblast growth factor 1 Son of sevenless homolog	A2RRV5 B3DGE3 E7F020 F1RC43 O57341 P48802 P79737 Q1XG76 Q38PL0 Q503B6 Q5MK87 Q5RKN6 Q5TLE1 Q5TLE2 Q6PBT8 Q6PC73 Q6SJP8 Q8AY90 Q90Z00 Q9DFC9	dob fb18e12 fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a fj59e07 frs3 grb2 grb2a grb2b hrasb hrasl id:ibd5158 kl nras si:dkey-21e2.2 si:dkeyp-74c5.3 sos1 wu:fb05c08 wu:fb18e12 wu:fb34e06 wu:fc89b01 wu:fd11d03 wu:fj59e07 zgc:103549 zgc:109774 zgc:110734 zgc:158274 zgc:194535 zgc:73077	Danio rerio (zebrafish)
Downstream signaling of activated FGFR1	Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine-rich transmembrane protein 1b Fibronectin leucine-rich transmembrane protein 2 Klotho Putative fibroblast growth factor 1	B3DGE3 F1QF54 F1RC43 O57341 P48802 Q1XG76 Q38PL0 Q5MK87 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q8AY90 Q90Z00 Q9DFC9 X1WEV4	dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a flrt1b flrt2 id:ibd5158 kl si:dkey-21e2.2 si:dkey-87k14.1 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 zgc:109774 zgc:194535	Danio rerio (zebrafish)
SHC-mediated cascade:FGFR1	Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Klotho Putative fibroblast growth factor 1 Son of sevenless homolog	A2RRV5 B3DGE3 F1RC43 O57341 P48802 P79737 Q1XG76 Q38PL0 Q503B6 Q5MK87 Q5RKN6 Q5TLE1 Q5TLE2 Q6PBT8 Q6PC73 Q6SJP8 Q8AY90 Q90Z00 Q9DFC9	dob fb18e12 fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a fj59e07 grb2 grb2a grb2b hrasb hrasl id:ibd5158 kl nras si:dkey-21e2.2 si:dkeyp-74c5.3 sos1 wu:fb05c08 wu:fb18e12 wu:fb34e06 wu:fc89b01 wu:fd11d03 wu:fj59e07 zgc:103549 zgc:109774 zgc:110734 zgc:158274 zgc:194535 zgc:73077	Danio rerio (zebrafish)
PI-3K cascade:FGFR1	Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Klotho Phosphatidylinositol 3-kinase regulatory subunit alpha Putative fibroblast growth factor 1 phosphatidylinositol-4,5-bisphosphate 3-kinase	B0S6V7 B3DGE3 F1QAD7 F1RC43 O57341 P48802 Q1XG76 Q38PL0 Q5MK87 Q5RKN6 Q5TLE1 Q5TLE2 Q6PBT8 Q6PC73 Q6SJP8 Q8AY90 Q90Z00 Q9DFC9	dob fb18e12 fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a grb2 grb2a grb2b id:ibd5158 kl pik3ca pik3r1 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fb05c08 wu:fb18e12 wu:fb34e06 wu:fb65b05 wu:fc89b01 wu:fd11d03 zgc:103549 zgc:109774 zgc:194535 zgc:73077	Danio rerio (zebrafish)
FGFR1c and Klotho ligand binding and activation	Fgf23 Fibroblast growth factor receptor 1-A Klotho	F1RC43 Q5MK87 Q90Z00	fgf23 fgfr1 fgfr1a kl	Danio rerio (zebrafish)
FGFR1b ligand binding and activation	Fibroblast growth factor 3 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GAIP c-terminus interacting protein 1 Putative fibroblast growth factor 1 Transforming growth factor beta receptor III	A0A0H3UK16 B3DGE3 P48802 Q1XG76 Q6B337 Q6PBT8 Q8AY90 Q90Z00	GIPC TIP-2 fgf-1 fgf-10 fgf-3 fgf1 fgf10 fgf10a fgf2 fgf22 fgf3 fgfr1 fgfr1a gipc1 rgs19ip1 si:ch73-18k18.1 si:dkey-21e2.2 si:dkeyp-74c5.3 tgfbr3 wu:fd11d03 zgc:109774	Danio rerio (zebrafish)
FGFR2b ligand binding and activation	Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DHR9 P48802 Q1XG76 Q6PBT8 Q8AY90 Q8JG38	fgf-1 fgf-10 fgf-3 fgf1 fgf10 fgf10a fgf22 fgf3 fgf7 fgfr2 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fd11d03 zgc:109774	Danio rerio (zebrafish)
Keratan sulfate degradation	Fibromodulin Keratocan Lumican Mimecan N-acetylglucosamine-6-sulfatase	Q4V902 Q4V9E0 Q5BLC1 Q5RI43 Q6IQQ7	Lum fmoda gnsa im:6910494 kera lum ogn ogna si:ch211-103f16.4 zgc:113456 zgc:113545 zgc:114066 zgc:86661	Danio rerio (zebrafish)	G20239CJ G80016QC
Antagonism of Activin by Follistatin	Follistatin-A Follistatin-like 3 (secreted glycoprotein) Inhibin beta A chain Inhibin beta B chain	A1L1T8 A4IG14 B0S7E0 Q9YHV4	actbb actbetaB fst fst1 fsta fstl3 inhbab inhbal inhbb si:dkey-28h18.3 zgc:114170 zgc:158348	Danio rerio (zebrafish)
GDP-fucose biosynthesis	Fucose mutarotase GDP-L-fucose synthase	Q5SPD5 Q7ZZ03	fuom gfus gfus.1 si:dkey-235d18none tsta3 zgc:101805	Danio rerio (zebrafish)	G85196CF G96881BQ
NGF processing	Furin (paired basic amino acid cleaving enzyme) a Nerve growth factor Proprotein convertase subtilisin/kexin type 5 preproprotein	F1QQ43 Q069L0 Q6YBR5	PCSK5 furin furina ngf ngfb pcsk5 pcsk5b si:dkey-281a24.5 zgc:165659	Danio rerio (zebrafish)
Signaling by PDGF	Furin (paired basic amino acid cleaving enzyme) a Platelet-derived growth factor receptor alpha Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Tyrosine-protein phosphatase non-receptor type 12	A0A2R8Q0D8 F1QQ43 Q08CD2 Q6PEI4 Q9DE49	furin furina pdgfab pdgfbb pdgfra ptpn12 si:dkey-281a24.5 wu:fc32c12 zgc:153249 zgc:65856 zgc:77437	Danio rerio (zebrafish)
Inactivation, recovery and regulation of the phototransduction cascade	G protein-coupled receptor kinase Glycylpeptide N-tetradecanoyltransferase 2 Glycylpeptide N-tetradecanoyltransferase Guanine nucleotide-binding protein (G protein), alpha transducing activity polypeptide 1 Guanine nucleotide-binding protein subunit gamma Guanylate cyclase activating protein 4 Guanylate cyclase activator 1C Guanylyl cyclase-activating protein 1 Guanylyl cyclase-activating protein 1 Guanylyl cyclase-activating protein 2 Methionine aminopeptidase 1 Methionine aminopeptidase 2 Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Recoverin Rhodopsin kinase grk7-b Rhodopsin S-arrestin	A1L1V1 A7YT82 P35359 Q1XHL7 Q1XHM0 Q4QRK0 Q4V8S2 Q4VBR7 Q6IQG3 Q6NUV2 Q6PBN9 Q6PFM5 Q6ZM98 Q7SXK1 Q8UUX9 Q90WX3 Q90WX4 Q90WX6	GRK1A GUCA1D METAP2 fk56b01 fk56e06 fnta fntb gcap1 gcap2 gcap3 gcap4 gcap5 gnat1 gng1 gngt1 grk1 grk1a grk7-2 grk7b guca1a guca1aa guca1ab.1 guca1b guca1c guca1d guca1e im:2601337 im:6909421 metap1 metap2 metap2b nmt-1 nmt1 nmt1a nmt2 rcv1a rcvrna rho saga si:rp71-1p14.1 wu:fb51d12 wu:fb98h06 wu:fb99h09 wu:fc15d01 wu:fc18a04 wu:fk53d06 wu:fk56b01 wu:fk56e06 wu:fz92f09 zfo2 zgc:110714 zgc:114180 zgc:158397 zgc:66109 zgc:66243 zgc:66250 zgc:73318 zgc:85885 zgc:86774	Danio rerio (zebrafish)
Class C/3 (Metabotropic glutamate/pheromone receptors)	G-protein coupled receptor family C group 6 member A Glutamate receptor, metabotropic 1b Glutamate receptor, metabotropic 2b Glutamate receptor, metabotropic 6a isoform X1 Glutamate receptor, metabotropic 8a Metabotropic glutamate receptor 3 Metabotropic glutamate receptor 5 precursor Taste receptor type 1 member 2 Taste receptor type 1 member 2b Taste receptor type 1 member 3 Taste receptor type 2 Taste receptor type 2 Taste receptor, type 1, member 2, tandem duplicate 1	A0A0R4IRN2 A0A0R4IU63 A3KPM6 A4PHQ8 E7F7E9 E7FH00 Q2MHK8 Q2MHK9 Q2MHL1 Q2MHL2 Q58WW7 Q5U9X3 U3N5Y5	T2R2 TAS1R1 TAS1R2a TAS1R3 TAS2R1a TAS2R1b Tas1R2b gb:kf234084 gprc6a grm1 grm1b grm2b grm3 grm5a grm5b grm6a grm7 grm8a si:ch211-233h19.1 si:ch211-278p9.5 si:dkey-52h10.3 t1rc1 tas1r1 tas1r2.1 tas1r2.2 tas1r2a tas1r2b tas1r3 tas2r1a tas2r200.1 tas2r200.2 tas2r2l	Danio rerio (zebrafish)	G58161NS
Synthesis of glycosylphosphatidylinositol (GPI)	GPI ethanolamine phosphate transferase 1 GPI mannosyltransferase 3	E7EXW2 Q7SXZ1	pigb pign zgc:172324	Danio rerio (zebrafish)
Signaling by SCF-KIT	GRB2 related adaptor protein a GRB2-related adaptor protein 2 GTPase HRas GTPase NRas Grb10 protein Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Kit ligand Mast/stem cell growth factor receptor kita Matrix metalloproteinase-9 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphoinositide-3-kinase, regulatory subunit 3A (gamma) Proto-oncogene tyrosine-protein kinase Src Receptor-type tyrosine-protein phosphatase U Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Son of sevenless homolog Tyrosine-protein kinase fynb Tyrosine-protein kinase yes Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0R4IUJ2 A1A5H8 A2RRV5 A9ULT3 B0S6V7 B3DGV1 B3DHG9 B3DK56 C0RW38 F1QAD7 F1RDG9 O93598 P79737 Q1JPZ3 Q1RLY5 Q503B6 Q503S8 Q567F1 Q56JH6 Q5RKN6 Q68EG5 Q68SP2 Q68SP3 Q6PC73 Q7T317 Q8JFR5	JAK2bCA Stat5 ZFMMP-9 fb18e12 fj05a08 fj21h04 fj59e07 fynb grap grap2a grapa grb10 grb10a grb2 grb2a grb2b hrasb hrasl jak2 jak2b kit kita kitla kitlga lck mmp9 nras pik3ca pik3r1 pik3r2 pik3r3a ptpru rptppsi sb:eu508 sb:eu615 sos1 sparse src stat1 stat1a stat5 stat5.1 stat5.2 stat5a stat5b stat6 stat7 tec wu:fb02g06 wu:fb07b05 wu:fb16a12 wu:fb18e12 wu:fb34e06 wu:fb65b05 wu:fi98c09 wu:fj05a08 wu:fj21h04 wu:fj59e07 wu:fj66g07 wu:fk56b03 yes yes1 zgc:103549 zgc:110202 zgc:110734 zgc:112091 zgc:136695 zgc:158274 zgc:64165 zgc:73077 zgc:73230 zgc:91987	Danio rerio (zebrafish)
Amino acids regulate mTORC1	GTP-binding protein Rheb H(+)-transporting two-sector ATPase Neutral amino acid transporter 9 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory-associated protein of MTOR, complex 1 SH3 domain-binding protein 4-A Serine/threonine-protein kinase TOR Target of rapamycin complex subunit lst8 V-type proton ATPase proteolipid subunit V-type proton ATPase subunit C 1-A V-type proton ATPase subunit D V-type proton ATPase subunit E 1 V-type proton ATPase subunit F V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit a V-type proton ATPase subunit d 1 V-type proton ATPase subunit Vacuolar proton pump subunit B	A0A0R4IFI0 B0R0V8 E7FA90 E7FCD8 Q06RG6 Q08BA4 Q0P3X8 Q1LVQ2 Q502N9 Q503S6 Q504A1 Q6DEG4 Q6DRK0 Q6P041 Q6PBR5 Q6PC18 Q6PGV1 Q7T385 Q7ZUI2 Q7ZVM7 Q7ZVX8 Q803V5 Q8JHH4 Q8QHA7	RRAGB atp6e atp6v0cb atp6v0d1 atp6v1ab atp6v1ba atp6v1c1 atp6v1c1a atp6v1d atp6v1e1 atp6v1e1b atp6v1f atp6v1g1 atp6v1h atpv0e2 cb927 chunp6890 chunp6932 cto fb52g11 fj35f08 frap1 gbl lamtor2 lamtor3 lamtor4 lamtor5 lst8 mapksp1 mlst8 mtor rheb rptor rraga rragc rragca sh3bp4 sh3bp4a si:dkey-176g4.2 slc38a9 tcirg1 tcirg1b tor vatB1 wu:fa12a02 wu:fb44e06 wu:fb52g11 wu:fc22h08 wu:fc68h09 wu:fc74d11 wu:fi46h07 wu:fj35f08 wu:fq38h02 zgc:109987 zgc:111904 zgc:111971 zgc:55524 zgc:56499 zgc:73144 zgc:73282 zgc:77708 zgc:92923	Danio rerio (zebrafish)
Regulation of PTEN gene transcription	GTP-binding protein Rheb Neutral amino acid transporter 9 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory-associated protein of MTOR, complex 1 Repressor of RNA polymerase III transcription MAF1 Serine/threonine-protein kinase TOR Target of rapamycin complex subunit lst8	A0A0R4IFI0 E7FA90 Q06RG6 Q08BA4 Q0P3X8 Q4V9H8 Q502N9 Q503S6 Q6DEG4 Q6PC18 Q7ZUI2 Q803V5	RRAGB frap1 gbl lamtor2 lamtor3 lamtor4 lamtor5 lst8 maf1b mapksp1 mlst8 mtor rheb rptor rraga rragc rragca si:ch73-174h16.3 si:dkey-176g4.2 slc38a9 tor wu:fc22h08 wu:fc68h09 wu:fi23d09 zgc:111971 zgc:56499 zgc:73144	Danio rerio (zebrafish)
Electric Transmission Across Gap Junctions	Gap junction protein Gap junction protein Pannexin-1 Pannexin	B0FL75 B1P2E8 Q7ZUN0 Q8JFD6	PANX connexin35 cx35 cx35b cx52.7 gja10a gja9 gjd2b panx1 panx1a panx2 si:ch211-192n14.2 zgc:194445 zgc:194451 zgc:55631	Danio rerio (zebrafish)
Synthesis, secretion, and deacylation of Ghrelin	Ghrelin O-acyltransferase Ghrelin Growth hormone 1 Insulin-like growth factor 1 Insulin Leptin Neuroendocrine convertase 1 Signal peptidase complex catalytic subunit SEC11 Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3	B1Q006 B6VCA1 C4WYH6 O73727 Q1JQ34 Q3ZV42 Q499B2 Q5BJI9 Q6DGR3 Q6NWJ2 Q90VV9	IGF-1 IGF-1L IGF-1a IGF-I fa97f07 gh1 ghl ghr ghre ghrl goat igf1 ins lepb mboat4 ob-b pcsk1 sec11 sec11a sec11l1 si:dkey-21o22.1 spcs1 spcs2 spcs3 wu:fa97f07 zgc:110014 zgc:85675 zgc:92805	Danio rerio (zebrafish)	G58161NS
Intestinal hexose absorption	Glucose transporter 2 Sodium/glucose cotransporter 1	Q102R8 Q6NWE6	glut2 slc2a2 slc5a1 wu:fb62h10 zgc:66074 zgc:85782	Danio rerio (zebrafish)	G58161NS G93924TT
Glycerophospholipid catabolism	Glycerophosphocholine cholinephosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1	Q5BKW7 Q7ZUV3	enpp6 gde1 zgc:56068 zgc:77135	Danio rerio (zebrafish)

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