GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **252** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
FRS-mediated FGFR4 signaling	FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Putative fibroblast growth factor 1 Son of sevenless homolog	A2RRV5 B3DGE3 E7F020 O57341 P79737 Q2HXK8 Q38PL0 Q503B6 Q5MK87 Q5RKN6 Q5TKR8 Q5TLE1 Q6PBT8 Q6PC73 Q6SJP8 Q90413 Q9DFC9	dob fb18e12 fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf6b fgf8 fgf8a fgfr4 fj59e07 frs3 grb2 grb2a grb2b hrasb hrasl id:ibd5158 nras sos1 wu:fb05c08 wu:fb18e12 wu:fb34e06 wu:fc89b01 wu:fj59e07 zgc:103549 zgc:110734 zgc:158274 zgc:194535 zgc:73077	Danio rerio (zebrafish)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 B3DHR9 O57341 P48802 Q1XG76 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q804J6 Q8AY90 Q8JG38 Q9DFC9	dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf7 fgf8 fgf8a fgfr2 fj46f04 id:ibd5158 plcg1 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 wu:fj46f04 wu:fj57a05 zgc:109774 zgc:194535	Danio rerio (zebrafish)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Putative fibroblast growth factor 1	B3DGE3 F1RC43 O57341 P48802 Q1XG76 Q38PL0 Q5MK87 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q804J6 Q8AY90 Q90Z00 Q9DFC9	dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a fj46f04 id:ibd5158 kl plcg1 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 wu:fj46f04 wu:fj57a05 zgc:109774 zgc:194535	Danio rerio (zebrafish)
Downstream signaling of activated FGFR1	Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine-rich transmembrane protein 1b Fibronectin leucine-rich transmembrane protein 2 Klotho Putative fibroblast growth factor 1	B3DGE3 F1QF54 F1RC43 O57341 P48802 Q1XG76 Q38PL0 Q5MK87 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q8AY90 Q90Z00 Q9DFC9 X1WEV4	dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a flrt1b flrt2 id:ibd5158 kl si:dkey-21e2.2 si:dkey-87k14.1 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 zgc:109774 zgc:194535	Danio rerio (zebrafish)
FGFR2c ligand binding and activation	FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q8JG38 Q9DFC9	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr2 id:ibd5158 wu:fb05c08 wu:fc89b01 zgc:194535	Danio rerio (zebrafish)
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE2 Q6PBT8 Q6SJP8 Q804J6 Q9DFC9 Q9I8X3	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf5 fgf8 fgf8a fgfr3 fj46f04 id:ibd5158 plcg1 wu:fb05c08 wu:fc89b01 wu:fj46f04 wu:fj57a05	Danio rerio (zebrafish)
FGFR3c ligand binding and activation	FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE2 Q6PBT8 Q6SJP8 Q9DFC9 Q9I8X3	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf5 fgf8 fgf8a fgfr3 id:ibd5158 wu:fb05c08 wu:fc89b01	Danio rerio (zebrafish)
Phospholipase C-mediated cascade; FGFR4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q6PBT8 Q6SJP8 Q804J6 Q90413 Q9DFC9	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf6b fgf8 fgf8a fgfr4 fj46f04 id:ibd5158 plcg1 wu:fb05c08 wu:fc89b01 wu:fj46f04 wu:fj57a05 zgc:194535	Danio rerio (zebrafish)
FGFR4 ligand binding and activation	FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q6PBT8 Q6SJP8 Q90413 Q9DFC9	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf6b fgf8 fgf8a fgfr4 id:ibd5158 wu:fb05c08 wu:fc89b01 zgc:194535	Danio rerio (zebrafish)
FGFR3b ligand binding and activation	FGF18a Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 3 Fibroblast growth factor Putative fibroblast growth factor 1	O57341 Q38PL0 Q5TKR8 Q6PBT8 Q6SJP8 Q9I8X3	dob fgf-1 fgf-8 fgf1 fgf17 fgf17b fgf18 fgf18a fgf20a fgf8 fgf8a fgfr3 wu:fb05c08	Danio rerio (zebrafish)
Glycerophospholipid catabolism	Glycerophosphocholine cholinephosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1	Q5BKW7 Q7ZUV3	enpp6 gde1 zgc:56068 zgc:77135	Danio rerio (zebrafish)
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Inositol-tetrakisphosphate 1-kinase Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A Phosphoinositide phospholipase C	A5D6R3 A7MD68 Q2I6J1 Q7ZZ56 Q804J6 X1WEB0	fa11a08 fb73f10 fc83f12 fd16b10 fj46f04 fk90e11 inppl1a itpk1b plcd1a plcd3a plcg1 pten ptenb ship2a si:bz1g13.4 wu:fa11a08 wu:fb73f10 wu:fc83f12 wu:fd16b10 wu:fj46f04 wu:fj57a05 wu:fk90e11 zgc:165641	Danio rerio (zebrafish)
Amino acid transport across the plasma membrane	Amino acid transporter Amino acid transporter Cationic amino acid transporter 2 High affinity cationic amino acid transporter 1 isoform X1 Large neutral amino acids transporter small subunit 3 Mitochondrial carnitine/acylcarnitine carrier protein CACL Monocarboxylate transporter 10 Proton-coupled amino acid transporter 4 Slc38a3 protein Sodium-coupled neutral amino acid symporter 2 Solute carrier family 3 (Amino acid transporter heavy chain), member 2b isoform X1 Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 7 Transporter Transporter Transporter Transporter Transporter Transporter Uncharacterized protein LOC790938 Y+L amino acid transporter 2	A0A2R8QFJ7 A1A5Y9 A1L1W9 A2RUY1 A5D8R6 A8WG91 D7RVS1 D7RVS2 E7F8C6 Q1LVJ1 Q1LVQ4 Q2VRP7 Q2YDQ4 Q4V8X8 Q59I64 Q5PR34 Q5SPB1 Q6DG25 Q6P3H9 Q6PBA3	fa11f11 fc26e12 fc51c07 id:ibd1327 sb:cb519 si:ch211-132b12.1 si:ch211-154h20.4 si:zc101n13.5 slc16a10 slc1a4 slc1a5 slc25a29 slc36a4 slc38a2 slc38a3 slc38a5b slc3a2b slc43a1b slc6a11 slc6a11a slc6a15 slc6a18 slc6a19 slc6a19b slc6a6 slc6a6b slc7a1 slc7a1a slc7a2 slc7a6 slc7a7 snat2 tau taut wu:fa01a01 wu:fa11f11 wu:fc26e12 wu:fc31c02 wu:fc48a10 wu:fc51c07 wu:fd58f10 wu:fe14a07 wu:fq18d12 zgc:114094 zgc:123300 zgc:158383 zgc:158423 zgc:172267 zgc:55813 zgc:66050 zgc:92015 zgc:92817	Danio rerio (zebrafish)
VEGFR2 mediated cell proliferation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 3-phosphoinositide-dependent protein kinase 1 Protein kinase C beta type Protein kinase C delta type Proto-oncogene tyrosine-protein kinase Src Vascular endothelial growth factor A-A Vascular endothelial growth factor receptor 2	O73682 Q1JPZ3 Q5GIT4 Q6NZV1 Q7SY24 Q7ZUC5 Q804J6	fb09d10 fj46f04 flk1b fv43b11 kdr kdrb pdpk1b plcg1 prkcb1 prkcbb prkcd prkcda src vegf vegfa vegfaa wu:fb09d10 wu:fj46f04 wu:fj57a05 wu:fv43b11 zgc:56558 zgc:77318	Danio rerio (zebrafish)
FGFRL1 modulation of FGFR1 signaling	FGF receptor-like protein 1a FGF18a Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Sprouty-related, EVH1 domain containing 1 Sprouty-related, EVH1 domain-containing protein 2	B3DGE3 O57341 P48802 Q1XG76 Q5MK87 Q5TKR8 Q5TLE2 Q6NV01 Q6NYK3 Q6SJP8 Q7SX76 Q8AY90 Q9DFC9	fb14c08 fc89b01 fgf-10 fgf-3 fgf-8 fgf10 fgf10a fgf17 fgf17b fgf18 fgf18a fgf2 fgf22 fgf23 fgf3 fgf4 fgf5 fgf8 fgf8a fgfrl1 fgfrl1a fj51c03 id:ibd5158 si:dkey-21e2.2 si:dkeyp-74c5.3 spred1 spred2 wu:fb14c08 wu:fc89b01 wu:fd11d03 wu:fj51c03 zgc:109774 zgc:64084 zgc:85707	Danio rerio (zebrafish)
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Lysine-specific demethylase 5B-B Transcription factor AP-2 gamma Transcriptional regulator Myc-B	Q5PQZ4 Q6IQX0 Q7ZVS9	fb48g05 fb49c04 jarid1b jarid1bb kdm5bb mycb tfap2c wu:fb48g05 wu:fb49c04 zgc:92088	Danio rerio (zebrafish)
Cellular hexose transport	Facilitated glucose transporter 1 Glucose transporter 2 Sodium-dependent glucose transporter 1 Sodium/glucose cotransporter 1 Sodium/glucose cotransporter 2 Sodium/glucose cotransporter 4 Solute carrier family 2 (Facilitated glucose transporter), member 8-like Solute carrier family 2 member 3b Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 45 member 3 precursor Sugar transporter SWEET1	A4QN56 A4QP56 A8WHP3 F1R0H0 F1R1M7 Q102R8 Q285P3 Q5EB14 Q6NWD8 Q6NWE6 Q6NWF1 Q7ZWH3	fc29a02 glut1 glut10 glut12 glut1a glut1b glut2 mfsd4b naglt1 rag1ap1 sb:cb753 sb:cb808 slc2a1 slc2a10 slc2a12 slc2a1a slc2a2 slc2a3b slc2a8 slc2a8l slc45a3 slc50a1 slc5a1 slc5a2 slc5a9 wu:fb62h10 wu:fc29a02 zgc:56364 zgc:66074 zgc:85782 zgc:85792	Danio rerio (zebrafish)	G58161NS G70323CJ
Regulation of insulin secretion	Facilitated glucose transporter 1 Glucose transporter 2	Q102R8 Q285P3	fc29a02 glut1 glut1a glut1b glut2 slc2a1 slc2a1a slc2a2 wu:fb62h10 wu:fc29a02	Danio rerio (zebrafish)	G58161NS
FGFR2b ligand binding and activation	Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DHR9 P48802 Q1XG76 Q6PBT8 Q8AY90 Q8JG38	fgf-1 fgf-10 fgf-3 fgf1 fgf10 fgf10a fgf22 fgf3 fgf7 fgfr2 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fd11d03 zgc:109774	Danio rerio (zebrafish)
FGFR1c and Klotho ligand binding and activation	Fgf23 Fibroblast growth factor receptor 1-A Klotho	F1RC43 Q5MK87 Q90Z00	fgf23 fgfr1 fgfr1a kl	Danio rerio (zebrafish)
Serine biosynthesis	Phosphoserine aminotransferase Phosphoserine phosphatase Serine incorporator 1 Serine incorporator 5	Q498V7 Q7SZW7 Q803I7 Q803X0	fi15b02 psat1 psph serinc1 serinc5 tde2 wu:fd02g01 wu:fd02g07 wu:fi15b02 zgc:112414 zgc:55738 zgc:77597 zgc:77622	Danio rerio (zebrafish)
N-glycan trimming and elongation in the cis-Golgi	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Glycoprotein endo-alpha-1,2-mannosidase	A3KQ03 E7EYY9	fi29h09 manea mgat1b si:ch211-152p11.3 wu:fi29h09 zgc:153912 zgc:92825	Danio rerio (zebrafish)	G58161NS
VEGF binds to VEGFR leading to receptor dimerization	C-fos induced growth factor Vascular endothelial growth factor A-A Vascular endothelial growth factor C Vascular endothelial growth factor receptor 2 Vascular endothelial growth factor receptor 3	O73682 Q208T6 Q5GIT4 Q5MD89 Q7T3I6	figf flk1b flt-4 flt4 kdr kdrb vegf vegf-d vegfa vegfaa vegfc vegfd vegfr3	Danio rerio (zebrafish)
VEGF ligand-receptor interactions	C-fos induced growth factor Vascular endothelial growth factor A-A Vascular endothelial growth factor C	O73682 Q208T6 Q7T3I6	figf vegf vegf-d vegfa vegfaa vegfc vegfd	Danio rerio (zebrafish)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase	B0V2X9	fj20e02 man1a2 si:dkey-174k18.8 wu:fj20e02	Danio rerio (zebrafish)	G70323CJ

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