GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **128** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Neutrophil degranulation	1-Cys peroxiredoxin 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 7 28 kDa heat- and acid-stable phosphoprotein homolog 5-hydroxyisourate hydrolase ABC transporter A family member 2 ABC transporter A family member 3 ABC transporter A family member 4 ABC transporter A family member 5 ABC transporter A family member 6 ADF-H domain-containing protein ADF-H domain-containing protein ADF-H domain-containing protein ADP-ribosylation factor-like protein 8 ADP-ribosylation factor-related ALA-interacting subunit AMP deaminase AP-1 complex subunit mu AP-2 complex subunit alpha-2 ATP-dependent DNA helicase ku70 Actin-related protein 10 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Adenosine deaminase 2 Adenylyl cyclase-associated protein Aldehyde dehydrogenase family 3 comG Alpha-L-fucosidase Alpha-actinin A Alpha-galactosidase Aminopeptidase Aminopeptidase Aminopeptidase Annexin A7 Annexin I Anoctamin transmembrane domain-containing protein Arginase/agmatinase/formiminoglutamase family protein Armadillo repeat-containing protein BEACH domain-containing protein lvsC Band 7 domain-containing protein Band 7 domain-containing protein Beta-galactosidase 1 Beta-hexosaminidase subunit B2 CN hydrolase domain-containing protein COMM domain-containing protein 3 CSC1/OSCA1-like 7TM region domain-containing protein CSC1/OSCA1-like 7TM region domain-containing protein CTL-like protein DDB_G0288717 Calmodulin-binding protein Calmodulin-like protein Calmodulin Calponin-homology (CH) domain-containing protein Calponin-homology (CH) domain-containing protein Calponin-homology (CH) domain-containing protein Casein kinase II subunit beta Catalase-A Cathepsin B Cathepsin D Cell division cycle protein 48 Centractin Choline transporter-like protein 2 Coatomer subunit beta Copine-A Copine-B Copine-C Copine-D Copine-E Copine-F Countin-3 Counting factor 60 Counting factor associated protein D Cullin-associated NEDD8-dissociated protein 1 Culmination specific protein 37D Cystatin-A1 Cystatin-A2 Cystatin-A3 Cysteine proteinase 2 Cysteine proteinase 3 Cysteine proteinase 4 Cysteine proteinase 5 Cysteine proteinase 6 Cysteine proteinase 7 Cytochrome b5 domain-containing protein Cytoplasmic dynein 1 light intermediate chain 1 DOCK family protein DOCK family protein DUF2470 domain-containing protein Delta-aminolevulinic acid dehydratase Diacylglycerol O-acyltransferase 1 DnaJ homolog subfamily C member 3 homolog Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Drebrin-like protein Dynein heavy chain, cytoplasmic Dynein light chain Tctex-type Dynein light chain, cytoplasmic EGF-like domain-containing protein Elongation factor 1-alpha Elongation factor 1-alpha Elongation factor 2 Extracellular signal-regulated kinase 1 Filament-interacting protein Fructose-bisphosphate aldolase Gamete and mating-type specific protein A Gamma-glutamyl hydrolase B Gelsolin-related protein of 125 kDa Gelsolin-related protein Glucose-6-phosphate isomerase Glutaminyl-peptide cyclotransferase Glutathione S-transferase domain-containing protein DDB_G0273153/DDB_G0273923 Glycogen debranching enzyme Glycogen phosphorylase 1 Glycogen phosphorylase 2 HECT-type E3 ubiquitin transferase HP domain-containing protein Heat shock 70-related protein 5 Heat shock cognate 70 kDa protein 1 Heat shock cognate 70 kDa protein 2 Heat shock cognate 70 kDa protein 3 Heat shock cognate 70 kDa protein 4 Heat shock cognate 90 kDa protein IST1-like protein Inosine-5'-monophosphate dehydrogenase Interaptin Isocitrate dehydrogenase [NADP], mitochondrial J domain-containing protein Leucine aminopeptidase Lipoxygenase domain-containing protein Lysosomal alpha-mannosidase Lysosome membrane protein 2-A Lysosome membrane protein 2-B Lysosome membrane protein 2-C MD-2-related lipid-recognition domain-containing protein MD-2-related lipid-recognition domain-containing protein MHD2 domain-containing protein MRH domain-containing protein Major sperm protein domain-containing protein Major vault protein alpha Maltase Metal transporter nramp1 homolog Methyltransferase domain-containing protein Methyltransferase domain-containing protein Mo25-like family protein Myosin-ID light chain NADH-cytochrome b5 reductase 1 Nck-associated protein 1 homolog Nicastrin Nicotinate phosphoribosyltransferase Nitrilase homolog 2 Non-histone chromosomal protein 6 homolog Nucleoside diphosphate kinase, cytosolic Nucleoside diphosphate kinase, mitochondrial P2X receptor A P2X receptor B P2X receptor C P2X receptor D P2X receptor E Peptidase S28 family protein Peptidase S28 family protein Peroxinectin A Peroxiredoxin-4 Phosphoglucomutase-1 Phospholipase D A Phospholipase D B Phospholipase D C Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid/glycerol acyltransferase domain-containing protein Presenilin-A Presenilin-B Prespore protein Dd31 Probable ATP-citrate synthase Probable ATP-dependent RNA helicase ddx3 Probable E3 ubiquitin-protein ligase DDB_G0283893 Probable acid phosphatase DDB_G0284753 Probable acid phosphatase DDB_G0284755 Probable alpha-galactosidase Probable cyclin-dependent serine/threonine-protein kinase DDB_G0278487 Probable cytidine deaminase Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 Probable inactive serine/threonine-protein kinase DDB_G0280855 Probable phosphoglucomutase-2 Probable phosphoglycerate mutase Probable serine/threonine-protein kinase DDB_G0288795 Probable serine/threonine-protein kinase cdc7 Probable serine/threonine-protein kinase kinase DDB_G0280557 Probable serine/threonine-protein kinase kinase DDB_G0280643 Proliferation-associated protein A Proteasome subunit alpha type-2 Proteasome subunit alpha type-5 Proteasome subunit beta type-7 Protein kinase domain-containing protein Protein pirA Protein yippee-like Protovillin Putative calpain-like cysteine protease A Putative glutathione S-transferase alpha-1 Putative glutathione S-transferase alpha-2 Putative glutathione S-transferase alpha-3 Putative glutathione S-transferase alpha-4 Putative glutathione S-transferase alpha-5 Putative phosphatidylglycerol/phosphatidylinositol transfer protein 1 Putative phosphatidylglycerol/phosphatidylinositol transfer protein 2 Putative phosphatidylglycerol/phosphatidylinositol transfer protein 3 Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0278295 Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282107 Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179 Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0285639 Pyridoxal kinase Pyruvate kinase RAC family serine/threonine-protein kinase homolog Rab GDP dissociation inhibitor Rab GTPase Rab GTPase Rab GTPase RabGAP/TBC domain-containing protein RabGAP/TBC domain-containing protein RabGAP/TBC domain-containing protein Ragulator complex protein LAMTOR3 homolog Ras GTPase-activating-like protein gapA Ras GTPase-activating-like protein rgaA Ras modification protein ERF4 Ras-related protein Rab-14 Ras-related protein Rab-18 Ras-related protein Rab-1C Ras-related protein Rab-24 Ras-related protein Rab-32D Ras-related protein Rab-4 Ras-related protein Rab-5A Ras-related protein Rab-6 Ras-related protein Rab-7B Ras-related protein Rab-7a Ras-related protein Rab-8A Ras-related protein Rab-8B Ras-related protein RabK1 Ras-related protein RabK2 Ras-related protein RabK3 Ras-related protein RabL Ras-related protein RabM Ras-related protein RabN1 Ras-related protein RabN2 Ras-related protein RabR Ras-related protein RabT1 Ras-related protein RabT2 Ras-related protein RabV Ras-related protein RabX Ras-related protein RabZ Ras-related protein rapA Ras-related protein rapB Ras-related protein rapC Rho GTPase-activating protein gacJJ Rho GTPase Rho GTPase Rho-related protein rac1A Rho-related protein rac1B Rho-related protein rac1C Rho-related protein racB Rho-related protein racC Rho-related protein racD Rho-related protein racE Rho-related protein racF1 Rho-related protein racF2 Rho-related protein racH Rho-related protein racI Rho-related protein racJ Rho-related protein racL Rho-related protein racM Rho-related protein racN Rho-related protein racO Ribonuclease DdI Ribonuclease T2 Roadblock/LAMTOR2 domain-containing protein SH3 domain-containing protein SH3 domain-containing protein SH3 domain-containing protein SH3 domain-containing protein Saposin A Serine/threonine-protein kinase dst2 Severin Signal recognition particle 14 kDa protein Sugar transporter family protein Superoxide-generating NADPH oxidase heavy chain subunit A Superoxide-generating NADPH oxidase heavy chain subunit B Superoxide-generating NADPH oxidase heavy chain subunit C Synaptobrevin-A Synaptobrevin-B Synaptosomal-associated protein 47 T-complex protein 1 subunit beta T-complex protein 1 subunit theta Thioredoxin domain-containing protein Thioredoxin fold domain-containing protein Trafficking protein particle complex subunit 1 Transglycosylase SLT domain-containing protein Transmembrane protein Tubulin beta chain Type I phosphodiesterase/nucleotide pyrophosphatase family protein Tyrosine-protein phosphatase 1 Tyrosine-protein phosphatase 2 Tyrosine-protein phosphatase 3 UBX domain-containing protein UPF0522 protein C Ubiquitin-like modifier-activating enzyme atg7 Uncharacterized protein DDB_G0292160 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein V-type proton ATPase proteolipid subunit V-type proton ATPase subunit D VPS35 endosomal protein sorting factor-like Vacuolar proton translocating ATPase 100 kDa subunit Villidin X-ray repair cross-complementing protein 5 acetyl-CoA C-acyltransferase acylaminoacyl-peptidase alpha-L-fucosidase beta-mannosidase cathepsin X glutaminase non-specific serine/threonine protein kinase phospholipase D sphingolipid 4-desaturase t-SNARE coiled-coil homology domain-containing protein	C7FZY2 C7G009 C7G028 C7G034 O00897 O00899 O76173 O76329 O76856 O77229 O96390 O96621 O96626 O96923 P02599 P04989 P05095 P0CT31 P0CT32 P10733 P10901 P15112 P18613 P20790 P20791 P22887 P24639 P32256 P34036 P34093 P34098 P34114 P34118 P34137 P34138 P34144 P34145 P34146 P34148 P34149 P34150 P36410 P36411 P36415 P36418 P42525 P52922 P54637 P54639 P54640 P54642 P54644 P54651 P54654 P90532 Q00766 Q02465 Q1ZXA8 Q1ZXB3 Q1ZXB7 Q1ZXB8 Q1ZXB9 Q1ZXD3 Q1ZXE7 Q1ZXG2 Q1ZXG4 Q1ZXJ6 Q1ZXN9 Q23862 Q23894 Q23919 Q23924 Q54B14 Q54BC6 Q54BD8 Q54BE0 Q54BT5 Q54CI8 Q54CM5 Q54DA7 Q54DD0 Q54DE8 Q54DG1 Q54DK3 Q54DM7 Q54DN5 Q54DS6 Q54DW1 Q54E04 Q54E62 Q54EF8 Q54EG4 Q54ES9 Q54ET2 Q54EU4 Q54F41 Q54F44 Q54F59 Q54F95 Q54FG5 Q54FK2 Q54FK4 Q54FK5 Q54FK7 Q54FK8 Q54FU0 Q54FY7 Q54GB3 Q54GE1 Q54GY8 Q54H23 Q54H32 Q54HL4 Q54HS9 Q54HT4 Q54HV8 Q54HZ7 Q54I20 Q54I39 Q54I48 Q54I79 Q54I82 Q54IC2 Q54IF2 Q54IJ2 Q54J33 Q54JH4 Q54JM5 Q54JM9 Q54JT7 Q54JY2 Q54JY8 Q54K32 Q54K56 Q54K65 Q54K69 Q54K94 Q54KP7 Q54L24 Q54L55 Q54LD6 Q54LX9 Q54LY5 Q54LZ3 Q54M21 Q54MA9 Q54ME1 Q54MJ8 Q54MR6 Q54MV4 Q54N33 Q54N82 Q54NC1 Q54NE6 Q54NQ0 Q54NT2 Q54P07 Q54P51 Q54P71 Q54P72 Q54PB7 Q54PF1 Q54PG1 Q54PN7 Q54PR9 Q54PW0 Q54Q49 Q54Q68 Q54QD9 Q54QG5 Q54QK4 Q54QQ0 Q54QR2 Q54QS3 Q54QV7 Q54R04 Q54R55 Q54RF5 Q54RQ2 Q54RR3 Q54RX2 Q54RY4 Q54S11 Q54S39 Q54S93 Q54SE2 Q54SW1 Q54SW2 Q54SZ8 Q54SZ9 Q54TL9 Q54TR1 Q54U08 Q54U63 Q54U95 Q54UB5 Q54UI8 Q54UI9 Q54UJ0 Q54UK0 Q54UQ2 Q54US6 Q54V35 Q54V78 Q54V83 Q54VI4 Q54W35 Q54WG1 Q54WI8 Q54WK5 Q54WQ8 Q54WR4 Q54XS7 Q54XV8 Q54Y06 Q54Y60 Q54YA0 Q54YD2 Q54YE6 Q54YY4 Q54Z16 Q54Z25 Q54Z55 Q54Z85 Q550I3 Q550W0 Q551C1 Q551I6 Q551J1 Q552H0 Q552J0 Q552S3 Q553R6 Q553U5 Q553Y0 Q553Y1 Q555L5 Q555Z5 Q556G3 Q556L1 Q556P3 Q556T3 Q556U5 Q556Z2 Q557E0 Q557G3 Q557H3 Q557I4 Q557J6 Q559U0 Q55B10 Q55BA2 Q55BH9 Q55BL4 Q55BQ8 Q55BW0 Q55C24 Q55C75 Q55CB2 Q55CT4 Q55CY7 Q55D50 Q55D65 Q55D94 Q55D97 Q55E06 Q55E61 Q55EF0 Q55EG6 Q55EK9 Q55FF3 Q55FK2 Q55FM7 Q55FQ9 Q55FR5 Q55FS4 Q55FU1 Q55FU9 Q55G04 Q55G10 Q55GA1 Q55GA9 Q55GC2 Q55GG1 Q55GN5 Q5R1U3 Q5V9E9 Q65YR7 Q65YR8 Q6TMJ9 Q6TMK4 Q6UK63 Q75JR2 Q75JR4 Q75JX3 Q7KWP5 Q7M438 Q7YXU4 Q7Z2B8 Q869Q3 Q869V1 Q86A67 Q86A77 Q86A88 Q86AU1 Q86CR9 Q86GL4 Q86H52 Q86HR5 Q86HV8 Q86IJ1 Q86IY4 Q86J23 Q86JA1 Q86JM7 Q86JP3 Q86JP5 Q86K21 Q86KD1 Q86KI1 Q86L51 Q8MUF9 Q8T6J1 Q8T6J2 Q8T6J5 Q8WQ85 Q94503 Q94504 Q9BKJ9 Q9GPQ8 Q9GPQ9 Q9GPR2 Q9GPR7 Q9GPS3 Q9XYS3 Q9XYS8	ADA2 Arc15 Arp1 CP2 CP3 CP4 CP5 CP6 CP7 CatD DDB_G0267590 DDB_G0267742 DDB_G0267752 DDB_G0267952 DDB_G0267974 DDB_G0268034 DDB_G0269380 DDB_G0269774 DDB_G0270134 DDB_G0270454 DDB_G0271242 DDB_G0272220 DDB_G0272434 DDB_G0272742 DDB_G0273095 DDB_G0273153 DDB_G0273419 DDB_G0273473 DDB_G0274339 DDB_G0274461 DDB_G0274833 DDB_G0275535 DDB_G0275917 DDB_G0276227 DDB_G0276567 DDB_G0276661 DDB_G0276961 DDB_G0277093 DDB_G0277773 DDB_G0277967 DDB_G0278295 DDB_G0278401 DDB_G0278487 DDB_G0278563 DDB_G0278773 DDB_G0279493 DDB_G0279583 DDB_G0279675 DDB_G0280557 DDB_G0280565 DDB_G0280643 DDB_G0280855 DDB_G0281053 DDB_G0281055 DDB_G0281325 DDB_G0281401 DDB_G0281675 DDB_G0282107 DDB_G0282109 DDB_G0282177 DDB_G0282179 DDB_G0282517 DDB_G0282683 DDB_G0282859 DDB_G0282971 DDB_G0282991 DDB_G0283893 DDB_G0284155 DDB_G0284307 DDB_G0284753 DDB_G0284755 DDB_G0284997 DDB_G0285063 DDB_G0285639 DDB_G0285709 DDB_G0285897 DDB_G0286315 DDB_G0286691 DDB_G0286891 DDB_G0287185 DDB_G0287559 DDB_G0287731 DDB_G0288717 DDB_G0288795 DDB_G0288847 DDB_G0289029 DDB_G0289063 DDB_G0289195 DDB_G0289231 DDB_G0289735 DDB_G0289749 DDB_G0290593 DDB_G0290995 DDB_G0291131 DDB_G0291332 DDB_G0291524 DDB_G0291984 DDB_G0292160 DDB_G0293674 DDB_G0293678 DDB_G0294569 DDB_G0294571 DDB_G0294577 DDB_G0295811 DDB_G0295845 DG1029 Rab1C abcA2 abcA3 abcA4 abcA5 abcA6 abp1-1 abp1-2 abpA abpD abpE-1 abpE-2 acly actnA actnB actr10 actr11 agl akt alad alfA amdA ann7 ap2a1-1 ap2a1-2 apg7 apm1 arcE arl8 arlE armc8 arp10 arp11 arp2 arpA arpB arpH atg7 atp6v1d calA calB camA cand1 cap cat catA cct2 cct8 cda cdc7 cdcD cdk9-1 cdk9-2 cf60 cfaD comG commd3 copb cpiA cpiB cpiC cpl cplA cpnA cpnB-1 cpnB-2 cpnC cpnD cpnE cpnF cprB cprC cprD cprE cprF cprG csnk2b cspA ctl2 ctnC ctsB ctsD ctsZ cyb5r1 dagA ddi ddiA ddost ddx3 desA dgat1 dhcA dlcA dlcB dnajc13 dnajc3 docA docB docC docD dst2 dstB dync1li1 eef1a1 eef1a2 efaAI efaAII efaa1 efaa2 efbA erk1 erkA fba fip-1 fip-2 g6pi gaa gacJJ gapA gghB gip17 glb1 glpD glpV gmfA gmsA gnrA gnrB gnrC gpi gpmA gsta1 gsta2-1 gsta2-2 gsta3 gsta4 gsta5 gtr3 guaB guk hemB hexb2 hsc70 hsc90 hsp90 hspB hspD hspE-1 hspE-2 idhM impdh ku70 ku80 lipA lkhA lmpA lmpB lmpC lvsC manA mapbpip melA mlcD mvpA nap1 napA naprt ncstn ndkA ndkB ndkC-1 ndkC-2 ndkM nhp6 nit2 noxA noxB noxC nramp nramp1 nxnA nxnB orfR1062 ost3 ost48 p2xA p2xB p2xC p2xD p2xE pgam pgi pgmA pgmB pir121 pirA pkbA pld1 pldA pldB pldC poxA prdx4 prlA psaA psaB psenA psenB psmA2 psmA5 psmB7 psmC2 psmC3 psmD1 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD6 psmD7 ptp1 ptp2 ptp3 ptpA1-1 ptpA1-2 ptpB ptpC pyk pykA qpct rab14 rab18 rab24 rab32D rab4 rab5A rab6 rab7 rab7A rab7B rab8A rab8B rabD rabK1 rabK2 rabK3 rabL rabM rabN1 rabN2 rabR rabT1 rabT2 rabV rabX rabZ rac1A rac1B rac1C racB racC racD racE racF1 racF2 racH racI racJ racL racM racN racO racP racQ rap1 rapA rapB rapC rasGAP1 rcdC rgaA sapA sas1 sas2 sasA sasB sevA sks1 slc11a1 slc44a2 spiA srp14-1 srp14-2 sybA sybB symA tctel1 trappc1-1 trappc1-2 tubB vatM vatP veg125 vilA vilB vilD ypel	Dictyostelium discoideum
Detoxification of Reactive Oxygen Species	1-Cys peroxiredoxin Catalase-A Cytochrome c Extracellular superoxide dismutase [Cu-Zn] 2 Extracellular superoxide dismutase [Cu-Zn] 3 Glutathione S-transferase domain-containing protein DDB_G0273153/DDB_G0273923 Glutathione reductase Peroxiredoxin-4 Probable copper chaperone for superoxide dismutase Probable superoxide dismutase [Cu-Zn] 6 Putative glutathione S-transferase alpha-1 Putative glutathione S-transferase alpha-2 Putative glutathione S-transferase alpha-3 Putative glutathione S-transferase alpha-4 Putative glutathione S-transferase alpha-5 Putative thioredoxin-4 Superoxide dismutase [Cu-Zn] 4 Superoxide dismutase [Cu-Zn] 5 Superoxide dismutase [Mn], mitochondrial Superoxide-generating NADPH oxidase heavy chain subunit A Superoxide-generating NADPH oxidase heavy chain subunit B Superoxide-generating NADPH oxidase heavy chain subunit C Thioredoxin domain-containing protein Thioredoxin domain-containing protein Thioredoxin-3	O77229 P29447 Q1ZXE0 Q54F44 Q54F73 Q54G70 Q54N76 Q54NX3 Q54QV7 Q54RN1 Q54RQ1 Q54SE2 Q54TU5 Q54TW8 Q54VI4 Q555L5 Q556G3 Q556P3 Q55BJ9 Q55FF3 Q869N1 Q86AU1 Q86GL4 Q8T137 Q9XYS3	DDB_G0273153 DDB_G0282517 DDB_G0284939 cat catA ccs ccsA cytC gsr gsta1 gsta2-1 gsta2-2 gsta3 gsta4 gsta5 noxA noxB noxC prdx4 prdx5 sod2 sodB sodC sodD sodE sodF trx3 trx4 trxC trxD	Dictyostelium discoideum
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Calmodulin-like protein Calmodulin Inositol 5-phosphatase 4 Inositol 5-phosphatase Inositol-tetrakisphosphate 1-kinase Kinase LIM-domain containing phosphatase Myosin-ID light chain Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN Phospholipase D Y Phospholipase D Z Uncharacterized protein phosphoinositide 5-phosphatase	O00897 P02599 Q02158 Q54CH3 Q54D97 Q54JL7 Q54K50 Q54MG8 Q54SA1 Q54TI0 Q54W40 Q553B4 Q55D87 Q7Z2B8 Q8I7P3 Q8T9S7	DDB_G0275865 DDB_G0281737 DDB_G0285967 DDB_G0292920 Dd5P1 Dd5P3 Dd5P4 ITPK1 calA calB camA cnrN mlcD pipA plc pld3 pldY pldZ pteN ptenA	Dictyostelium discoideum
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase G-protein alpha subunit family protein Guanine nucleotide-binding protein alpha-1 subunit Guanine nucleotide-binding protein alpha-12 subunit Guanine nucleotide-binding protein alpha-2 subunit Guanine nucleotide-binding protein alpha-3 subunit Guanine nucleotide-binding protein alpha-4 subunit Guanine nucleotide-binding protein alpha-5 subunit Guanine nucleotide-binding protein alpha-6 subunit Guanine nucleotide-binding protein alpha-7 subunit Guanine nucleotide-binding protein alpha-8 subunit Guanine nucleotide-binding protein-like alpha-10 subunit Guanine nucleotide-binding protein-like alpha-11 subunit RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein	P16051 P16894 P34042 P34043 P34044 P34045 P34046 Q02158 Q54KV6 Q54LD1 Q54M81 Q54S99 Q54UG5 Q54VG1 Q54XJ6 Q556I3 Q55E55 Q55EP5 Q8T130	DDB_G0270858 DDB_G0273033 DDB_G0278897 DDB_G0282583 DDB_G0286173 DDB_G0286817 Ga3 gbqA gpa10 gpa11 gpa12 gpaA gpaB gpaC gpaD gpaE gpaF gpaG gpaH gpaJ gpaK gpaL pipA plc	Dictyostelium discoideum
PLC beta mediated events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase G-protein alpha subunit family protein Guanine nucleotide-binding protein alpha-1 subunit Guanine nucleotide-binding protein alpha-12 subunit Guanine nucleotide-binding protein alpha-2 subunit Guanine nucleotide-binding protein alpha-3 subunit Guanine nucleotide-binding protein alpha-4 subunit Guanine nucleotide-binding protein alpha-5 subunit Guanine nucleotide-binding protein alpha-6 subunit Guanine nucleotide-binding protein alpha-7 subunit Guanine nucleotide-binding protein alpha-8 subunit Guanine nucleotide-binding protein-like alpha-10 subunit Guanine nucleotide-binding protein-like alpha-11 subunit	P16051 P16894 P34042 P34043 P34044 P34045 P34046 Q02158 Q54KV6 Q54UG5 Q54VG1 Q55EP5 Q8T130	Ga3 gbqA gpa10 gpa11 gpa12 gpaA gpaB gpaC gpaD gpaE gpaF gpaG gpaH gpaJ gpaK gpaL pipA plc	Dictyostelium discoideum
TP53 Regulates Metabolic Genes	14-3-3-like protein 5'-AMP-activated protein kinase subunit gamma 5'-AMP-activated serine/threonine-protein kinase catalytic subunit alpha Association with the SNF1 complex (ASC) domain-containing protein GTP-binding protein Rheb homolog Glucose-6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glutathione reductase Peroxiredoxin-4 Probable serine/threonine-protein kinase DDB_G0288795 Probable serine/threonine-protein kinase MARK-B Protein LST8 homolog Protein raptor homolog Putative thioredoxin-4 RAC family serine/threonine-protein kinase homolog Ragulator complex protein LAMTOR3 homolog Ragulator complex protein LAMTOR4 homolog Ragulator complex protein LAMTOR5 homolog RapGAP/RanGAP domain-containing protein Ras-related GTP-binding protein A Ras-related GTP-binding protein Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase tor Sestrin homolog Thioredoxin domain-containing protein Thioredoxin-3 Uncharacterized protein DDB_G0292160	P29447 P54632 P54644 Q1ZXA8 Q1ZXE0 Q54D08 Q54DY3 Q54F59 Q54IF2 Q54IK1 Q54MV2 Q54N76 Q54PK6 Q54QW5 Q54UG7 Q54VB2 Q54WU6 Q54YF2 Q550Q4 Q555L5 Q557D2 Q55BR7 Q5V9E9 Q86C65 Q86J23 Q8T137 Q8T277	DDB_G0274833 DDB_G0279427 DDB_G0280527 DDB_G0283567 DDB_G0288795 DDB_G0291948 DDB_G0292160 akt ampka dagA fttB g6pd-1 g6pd-2 g6pi gpi gsr lst8 mapbpip mrkB pgi pkbA prdx4 prdx5 prkaa prkab prkag ragA ragC raptor rheb snfA tor trx3 trx4 trxC trxD zwf	Dictyostelium discoideum
Regulation of HSF1-mediated heat shock response	14-3-3-like protein Extracellular signal-regulated kinase 1 Glycogen synthase kinase-3 Heat shock 70 kDa protein, mitochondrial Heat shock 70-related protein 5 Heat shock cognate 70 kDa protein 1 Heat shock cognate 70 kDa protein 2 Heat shock cognate 70 kDa protein 3 Heat shock cognate 70 kDa protein 4 Heat shock factor-type DNA-binding domain-containing protein Heat shock protein 88 Luminal-binding protein 2 Myb domain-containing protein Protein OPI10 homolog	P36415 P42525 P51136 P54632 Q54BD8 Q54BE0 Q54MR6 Q54TH5 Q54UC1 Q54YL9 Q557E0 Q6TMK3 Q8I0H7 Q8T869	DDB_G0278179 DDB_G0281165 DDB_G0281747 DDB_G0285709 DDB_G0293674 DDB_G0293678 bip2 erk1 erkA fttB gsk3 gskA hsc70 hsp70 hspB hspE-1 hspE-2 hspH mhsp70	Dictyostelium discoideum
Peroxisomal protein import	2-Hydroxyacid oxidase 2-hydroxyacyl-CoA lyase 1 AB hydrolase-1 domain-containing protein Acyl-coenzyme A oxidase Catalase-A D-amino-acid oxidase Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial E2 ubiquitin-conjugating enzyme FAD dependent oxidoreductase domain-containing protein Insulin-degrading enzyme homolog Isocitrate dehydrogenase [NADP], mitochondrial Malonyl-CoA decarboxylase C-terminal domain-containing protein NADPH--cytochrome P450 reductase Nudix hydrolase domain-containing protein PXMP2/4 family protein 1 Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal targeting signal 1 receptor Peroxisomal targeting signal 2 receptor Peroxisome biogenesis factor 10 Phytanoyl-CoA dioxygenase Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable enoyl-CoA hydratase 2 Putative peroxisome assembly protein 12 Serine--pyruvate aminotransferase Ubiquitin conjugating enzyme E2 B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein acetyl-CoA C-acyltransferase hydroxymethylglutaryl-CoA lyase ubiquitinyl hydrolase 1	O77229 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 Q54C55 Q54CI0 Q54CL3 Q54DA9 Q54E41 Q54FX4 Q54GC2 Q54GK8 Q54GQ6 Q54GT6 Q54JQ2 Q54MD1 Q54N40 Q54QI7 Q54S31 Q54SF6 Q54SS0 Q54US8 Q54WA3 Q54XC3 Q54XZ0 Q54ZX5 Q553T4 Q556W1 Q55CT1 Q55FN8 Q75JR2 Q86IY4 Q8MMS1 Q94490	DDB_G0268018 DDB_G0274339 DDB_G0275415 DDB_G0277335 DDB_G0277477 DDB_G0279049 DDB_G0280851 DDB_G0282495 DDB_G0287851 DDB_G0290089 DDB_G0290277 DDB_G0290547 acox1 agxt cat catA ddo-1 ddo-2 ech1 hacl1 haox hmgL idhM mfe2 mfeB pex10 pex12 pex13 pex14 pex5 pex7 redB ubcB ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116	Dictyostelium discoideum
Glyoxylate metabolism and glycine degradation	2-Hydroxyacid oxidase Aspartate aminotransferase, mitochondrial D-amino-acid oxidase Proline dehydrogenase 1, mitochondrial Serine--pyruvate aminotransferase	Q54E41 Q54GT6 Q556W1 Q55F21 Q86H28	aatA agxt ddo-1 ddo-2 haox prodh	Dictyostelium discoideum
Antigen processing: Ubiquitination & Proteasome degradation	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 AAA+ ATPase domain-containing protein AAA+ ATPase, core domain-containing protein AAA+ ATPase, core domain-containing protein Aminopeptidase Aminopeptidase Aminopeptidase Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 13 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 3 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 6 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit 8 Anaphase-promoting complex subunit cdc20 Anaphase-promoting complex subunit cdc26 Anaphase-promoting complex subunit cdh1 Ankyrin repeat-containing protein Ankyrin repeat-containing protein B30.2/SPRY domain-containing protein BTB domain-containing protein BTB domain-containing protein BTB domain-containing protein BTB/POZ domain-containing protein Cullin-1 Cullin-2 Cullin-3 Cullin-5 Cyclin-like F-box containing protein Cyclin-like F-box containing protein E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E3 UFM1-protein ligase 1 homolog E3 ubiquitin-protein ligase cblA E3 ubiquitin-protein ligase listerin Elongin-C F-box domain-containing protein HECT-type E3 ubiquitin transferase E3D HECT-type E3 ubiquitin transferase HECT-type E3 ubiquitin transferase HECT-type E3 ubiquitin transferase Homeobox protein Wariai Kelch repeat-containing protein Leucine-rich repeat-containing protein MEK1 interacting protein 1 Myotrophin homolog NEDD8-activating enzyme E1 catalytic subunit NEDD8-conjugating enzyme Ubc12 NOSA Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Probable E3 ubiquitin-protein ligase DDB_G0283893 Probable E3 ubiquitin-protein ligase rbrA Probable ubiquitin-conjugating enzyme E2 C Probable ubiquitin-conjugating enzyme E2 N Probable ubiquitin-conjugating enzyme E2 W Probable ubiquitin-conjugating enzyme E2 variant Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein tirA Putative uncharacterized transmembrane protein DDB_G0290641 RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RCC1 domain-containing protein DDB_G0295713 RING finger domain and kelch repeat-containing protein DDB_G0271372 RING zinc finger-containing protein RING-box protein 1 RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type domain-containing protein RING-type domain-containing protein RING-type domain-containing protein Regulator of chromosome condensation domain-containing protein Regulator of chromosome condensation domain-containing protein Regulator of chromosome condensation domain-containing protein Regulator of chromosome condensation domain-containing protein Regulator of chromosome condensation domain-containing protein Rho GTPase-activating protein gacGG SCF ubiquitin ligase complex protein SKP1a SCF ubiquitin ligase complex protein SKP1b SH3 domain-containing protein Thimet-like oligopeptidase Trishanku UBC core domain-containing protein UBC core domain-containing protein UBC core domain-containing protein UBC core domain-containing protein UBR-type domain-containing protein Ubiquitin conjugating enzyme E2 B Ubiquitin-activating enzyme E1 C-terminal domain-containing protein Ubiquitin-conjugating enzyme E2 2 Ubiquitin-conjugating enzyme E2 J2 Ubiquitin-conjugating enzyme E2 S Ubiquitin-conjugating enzyme E2 Z Ubiquitin-conjugating enzyme E2 Ubiquitin-like domain-containing protein Ubiquitin-like modifier-activating enzyme 1 Ubiquitin-like modifier-activating enzyme 5 Ubiquitin-like modifier-activating enzyme atg7 Ubiquitin-protein ligase E3A Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein WD40 repeat-containing protein glutaminase	C7G034 C7G038 O44007 O60999 O76542 P02889 P0C7G9 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P52285 Q1ZXD3 Q1ZXE6 Q27562 Q27563 Q54BC4 Q54BC6 Q54BC8 Q54C02 Q54C30 Q54CI0 Q54D06 Q54D12 Q54D58 Q54D84 Q54DB2 Q54DD2 Q54DF3 Q54DL2 Q54DM7 Q54DN5 Q54DZ4 Q54EF6 Q54F41 Q54F46 Q54FX4 Q54FZ8 Q54GG5 Q54HT1 Q54HW1 Q54I00 Q54I29 Q54I43 Q54IL3 Q54J27 Q54J43 Q54J83 Q54JM5 Q54K33 Q54KM3 Q54KP2 Q54L05 Q54L48 Q54LP7 Q54LV9 Q54LZ6 Q54MZ3 Q54N05 Q54NC6 Q54NH2 Q54NI1 Q54NQ0 Q54NZ5 Q54PJ1 Q54PN7 Q54PV3 Q54Q05 Q54Q67 Q54QF1 Q54QG5 Q54QG9 Q54QR2 Q54QS0 Q54S82 Q54SG5 Q54SL8 Q54TE1 Q54TI6 Q54TL7 Q54TM9 Q54U33 Q54UB5 Q54UJ0 Q54UQ3 Q54V70 Q54VG3 Q54VV5 Q54VW7 Q54VW9 Q54VX1 Q54WI8 Q54WS8 Q54WU2 Q54XA6 Q54XF1 Q54XF7 Q54XG4 Q54XM7 Q54XS6 Q54Y77 Q54YU7 Q54YW2 Q550K3 Q550P1 Q550P6 Q550W4 Q551S9 Q552Y8 Q553E0 Q553F3 Q555G0 Q555H8 Q556Q0 Q557D0 Q557E4 Q557E7 Q557G6 Q557I4 Q557I6 Q557Q0 Q559F4 Q55AE0 Q55BF8 Q55BV5 Q55C16 Q55C75 Q55CM4 Q55CT4 Q55CY7 Q55D66 Q55DC5 Q55DY7 Q55ER5 Q55EY8 Q55FM5 Q55G04 Q55GE4 Q55GJ6 Q6T486 Q75JE1 Q75JS0 Q75JX5 Q86B11 Q86CR9 Q86IJ1 Q86JA1 Q86K32 Q86K42 Q8MP76 Q8T2Q2 Q94490 Q967U1 Q9XZJ3	DDB_G0268504 DDB_G0269704 DDB_G0270000 DDB_G0271372 DDB_G0271726 DDB_G0271956 DDB_G0272202 DDB_G0272218 DDB_G0272951 DDB_G0273381 DDB_G0273419 DDB_G0273451 DDB_G0273573 DDB_G0274897 DDB_G0275145 DDB_G0277011 DDB_G0277047 DDB_G0277053 DDB_G0277075 DDB_G0277249 DDB_G0277429 DDB_G0278049 DDB_G0278075 DDB_G0278671 DDB_G0278981 DDB_G0279003 DDB_G0279093 DDB_G0279435 DDB_G0279463 DDB_G0280089 DDB_G0280091 DDB_G0280347 DDB_G0280581 DDB_G0280895 DDB_G0281369 DDB_G0281657 DDB_G0281679 DDB_G0281833 DDB_G0282391 DDB_G0282479 DDB_G0283667 DDB_G0283893 DDB_G0283983 DDB_G0284145 DDB_G0284325 DDB_G0285063 DDB_G0285261 DDB_G0285581 DDB_G0285797 DDB_G0286289 DDB_G0286387 DDB_G0286991 DDB_G0287221 DDB_G0288345 DDB_G0288683 DDB_G0289043 DDB_G0289099 DDB_G0290547 DDB_G0290641 DDB_G0291131 DDB_G0291612 DDB_G0291902 DDB_G0291984 DDB_G0292144 DDB_G0292302 DDB_G0292362 DDB_G0292586 DDB_G0293756 DDB_G0295713 M4 anapc1 anapc10 anapc11 anapc2 anapc3 anapc4 anapc5 anapc6 anapc7 anapc8 apc1 apc10 apc11 apc2 apc3 apc4 apc5 apc6 apc7 apc8 apg7 atg7 cblA-1 cblA-2 cdc16 cdc20 cdc23 cdc26 cdc27 cdh1 cnrM cul1 cul2 cul3 cul5 culA culB culC culE dapA dpr1 fp21A fp21B fpa1 fpa1A fpa1B fpa2 fpaA fpaB-1 fpaB-2 gacGG hbx1 mip1-1 mip1-2 mtpn nosA prdD prdE prtC prtD psaA psaB psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 rbrA rbx1 rnf160 skp1A skp1B sks1 tbp2 tbpB tceb1 tirA triA uae1 uba1 uba3 uba5 ubc2 ubcB ubcC ubch10 ube1c ube2c ube2j2 ube2m ube2n ube2s ube2v ube2w ube3a ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116 warA wri	Dictyostelium discoideum
ABC-family proteins mediated transport	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 ABC transporter A family member 2 ABC transporter A family member 3 ABC transporter A family member 4 ABC transporter A family member 5 ABC transporter A family member 6 ABC transporter B family member 2 ABC transporter B family member 3 ABC transporter B family member 6 ABC transporter B family member 7 ABC transporter C family member 10 ABC transporter C family member 12 ABC transporter C family member 13 ABC transporter C family member 14 ABC transporter C family member 15 ABC transporter C family member 1 ABC transporter C family member 2 ABC transporter C family member 3 ABC transporter C family member 5 ABC transporter C family member 6 ABC transporter C family member 7 ABC transporter C family member 8 ABC transporter C family member 9 ABC transporter F family member 4 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Serine protease/ABC transporter B family protein tagA Serine protease/ABC transporter B family protein tagB Serine protease/ABC transporter B family protein tagC Serine protease/ABC transporter B family protein tagD Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein	P02889 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P54683 Q1ZXD3 Q23868 Q27562 Q27563 Q54BC6 Q54BC8 Q54BT3 Q54BT5 Q54CI0 Q54DB2 Q54DM7 Q54EK2 Q54HW1 Q54JM5 Q54JR2 Q54K24 Q54LE6 Q54NL1 Q54NQ0 Q54P13 Q54PJ1 Q54PN7 Q54QR2 Q54RU1 Q54S82 Q54T27 Q54U44 Q54UB5 Q54UJ0 Q54V86 Q54VC1 Q54VJ0 Q54WI8 Q54XD8 Q54XM7 Q552Y8 Q553E0 Q555Z5 Q556Q0 Q559F4 Q55BV5 Q55C75 Q55D66 Q55DA7 Q55DY7 Q55G04 Q55GJ6 Q869N9 Q86IJ1 Q86JA1 Q8ST87 Q8T6B4 Q8T6H3 Q8T6H8 Q8T6J1 Q8T6J2 Q8T6J5 Q8T9W1 Q8T9W4 Q967U1 Q9GTN7	DDB_G0272951 M4 abcA2 abcA3 abcA4 abcA5 abcA6 abcB2 abcB3 abcB6 abcB7 abcC1 abcC10 abcC12 abcC13 abcC14 abcC15 abcC2 abcC3 abcC5 abcC6 abcC7 abcC8 abcC9 abcF4 dapA dpr1 eif2G eif2a eif2b eif2s1 eif2s2 eif2s3 prdD prdE prtC prtD psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 sks1 tagA tagB tagC tagD tbp2 tbpB ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116	Dictyostelium discoideum
Neddylation	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 Ankyrin repeat-containing protein Ankyrin repeat-containing protein B30.2/SPRY domain-containing protein BTB domain-containing protein BTB domain-containing protein BTB domain-containing protein BTB/POZ domain-containing protein COMM domain-containing protein 10 COMM domain-containing protein 1 COMM domain-containing protein 2 COMM domain-containing protein 3 COMM domain-containing protein 4 COMM domain-containing protein 5 COMM domain-containing protein 6 COMM domain-containing protein 7 COMM domain-containing protein 8 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 7 COP9 signalosome complex subunit 8 Calponin-homology (CH) domain-containing protein Cell division cycle protein 48 Coiled-coil domain-containing protein 22 homolog Cullin-1 Cullin-2 Cullin-3 Cullin-4 Cullin-5 Cullin-associated NEDD8-dissociated protein 1 Cyclin-like F-box containing protein Cyclin-like F-box containing protein DCN1-like protein 1 DCN1-like protein 2 DDB1- and CUL4-associated factor 13 DDB1- and CUL4-associated factor 7 homolog DET1- and DDB1-associated protein 1 domain-containing protein DNA damage-binding protein 1 Defective in cullin neddylation protein Elongin-C F-box domain-containing protein Homeobox protein Wariai Kelch repeat-containing protein Myotrophin homolog NEDD8-activating enzyme E1 catalytic subunit NEDD8-activating enzyme E1 regulatory subunit NEDD8-conjugating enzyme Ubc12 NEDD8 Nuclear protein localization protein 4 homolog Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Probable histone-binding protein rbbD Probable ubiquitin carboxyl-terminal hydrolase Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RING finger domain and kelch repeat-containing protein DDB_G0271372 RING-box protein 1 RING-type domain-containing protein Retinoblastoma-binding-like protein E SCF ubiquitin ligase complex protein SKP1a SCF ubiquitin ligase complex protein SKP1b Trishanku UBR-type domain-containing protein UBX domain-containing protein 7 homolog Ubiquitin fusion degradation protein 1 homolog Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein WD repeat-containing protein 5 homolog WD40 repeat-containing protein WD40 repeat-containing protein WD40 repeat-containing protein WD40 repeat-containing protein	B0G147 B0M0P5 O60999 P02889 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P52285 P90532 Q1ZXD3 Q27562 Q27563 Q54B82 Q54BC6 Q54BC8 Q54C92 Q54CI0 Q54CS2 Q54CU8 Q54D84 Q54DB2 Q54DF3 Q54DL2 Q54DM7 Q54DR0 Q54DZ4 Q54E28 Q54E53 Q54F46 Q54GD3 Q54GP1 Q54HL6 Q54HW1 Q54I00 Q54IQ0 Q54IY4 Q54J43 Q54JM3 Q54JM5 Q54K33 Q54KL5 Q54LM6 Q54LV9 Q54MA5 Q54MH6 Q54MP2 Q54NQ0 Q54NZ5 Q54P14 Q54PF3 Q54PJ1 Q54PN7 Q54Q05 Q54Q43 Q54QG9 Q54QK4 Q54QR2 Q54QX3 Q54S82 Q54SD4 Q54T48 Q54TI6 Q54UB5 Q54UJ0 Q54UQ3 Q54V70 Q54WI8 Q54XA6 Q54XF7 Q54XM7 Q54XV3 Q54Y77 Q550I8 Q550W4 Q551N8 Q552R1 Q552Y8 Q553E0 Q554G3 Q556Q0 Q557E4 Q559F4 Q55BD5 Q55BF8 Q55BK0 Q55BU7 Q55BV5 Q55C56 Q55C75 Q55D66 Q55DE3 Q55DY7 Q55FM5 Q55G04 Q55GJ6 Q75JX5 Q75K24 Q7KWL3 Q86I14 Q86IJ1 Q86IW8 Q86JA1 Q86JC1 Q86JM4 Q86K42 Q86KD1 Q967U1 Q9XZJ3	DDB_G0269686 DDB_G0270220 DDB_G0271372 DDB_G0272016 DDB_G0272218 DDB_G0272666 DDB_G0272951 DDB_G0277011 DDB_G0277249 DDB_G0278671 DDB_G0279093 DDB_G0280581 DDB_G0280895 DDB_G0284157 DDB_G0284369 DDB_G0285813 DDB_G0286387 DDB_G0286565 DDB_G0288453 DDB_G0288597 DDB_G0289099 DDB_G0290025 DDB_G0291902 DDB_G0292144 DDB_G0292302 M4 appbp1 cand1 cdcD cnrM commd1 commd10 commd2 commd3 commd4 commd5 commd6 commd7 commd8 csn1 csn2 csn3 csn4 csn5 csn6 csn7 csn8 cul1 cul2 cul3 cul4 cul5 culA culB culC culD culE dapA ddb1 dpr1 ercc8 fp21A fp21B fpa1 fpa1A fpa1B fpa2 fpaA fpaB-1 fpaB-2 hbx1 mtpn nae1 nedd8 npl4 nploc4 prdD prdE prtC prtD psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 rbbD rbbE rbx1 repE skp1A skp1B sks1 tbp2 tbpB tceb1 triA uba3 ube1c ube2m ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO ubxd7 uch1 uchl ufd1 veg116 warA wdr23 wdr5 wdr68 wdsof1 wri	Dictyostelium discoideum
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 Aurora kinase Cullin-2 Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RING-box protein 1 SCF ubiquitin ligase complex protein SKP1a SCF ubiquitin ligase complex protein SKP1b Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein	P02889 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P52285 Q1ZXD3 Q27562 Q27563 Q54BC6 Q54BC8 Q54CI0 Q54DB2 Q54DM7 Q54HW1 Q54JM5 Q54K33 Q54NQ0 Q54PJ1 Q54PN7 Q54QR2 Q54S82 Q54UB5 Q54UJ0 Q54WI8 Q54WX4 Q54XM7 Q552Y8 Q553E0 Q556Q0 Q557E4 Q559F4 Q55BV5 Q55C75 Q55D66 Q55DY7 Q55G04 Q55GJ6 Q86IJ1 Q86JA1 Q967U1 Q9XZJ3	AurB Aurora DDB_G0272951 M4 aurK cul2 culB dapA dpr1 fp21A fp21B fpa1 fpa1A fpa1B fpa2 fpaA fpaB-1 fpaB-2 prdD prdE prtC prtD psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 rbx1 skp1A skp1B sks1 tbp2 tbpB ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116	Dictyostelium discoideum
KEAP1-NFE2L2 pathway	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 Autophagy-related protein 8-like protein DDB_G0290491 Autophagy-related protein 8 Cell division cycle protein 48 Cullin-3 Nuclear protein localization protein 4 homolog Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RING finger domain and kelch repeat-containing protein DDB_G0271372 RING-box protein 1 Sestrin homolog UBX domain-containing protein 7 homolog Ubiquitin fusion degradation protein 1 homolog Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein ZZ-type zinc finger-containing protein	P02889 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P90532 Q1ZXD3 Q27562 Q27563 Q54BC6 Q54BC8 Q54CI0 Q54DB2 Q54DM7 Q54G11 Q54GD3 Q54HW1 Q54JM5 Q54K33 Q54NQ0 Q54NZ5 Q54PJ1 Q54PN7 Q54QR2 Q54S82 Q54UB5 Q54UJ0 Q54WI8 Q54WU6 Q54XM7 Q552Y8 Q553E0 Q556Q0 Q559F4 Q55BF8 Q55BK0 Q55BU7 Q55BV5 Q55C75 Q55CE3 Q55D66 Q55DY7 Q55G04 Q55GJ6 Q86CR8 Q86IJ1 Q86JA1 Q967U1	DDB_G0270098 DDB_G0271372 DDB_G0272951 DDB_G0279427 DDB_G0290491 M4 apg8 atg8 cdcD cul3 culC dapA dpr1 npl4 nploc4 prdD prdE prtC prtD psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 rbx1 sks1 tbp2 tbpB ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO ubxd7 ufd1 veg116	Dictyostelium discoideum
Regulation of PTEN stability and activity	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 Casein kinase II subunit alpha Casein kinase II subunit beta HECT-type E3 ubiquitin transferase HECT-type E3 ubiquitin transferase LIM-domain containing phosphatase OTU domain containin protein Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Probable serine/threonine-protein kinase DDB_G0286481 Probable serine/threonine-protein kinase DDB_G0288795 Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RAC family serine/threonine-protein kinase homolog RING-type E3 ubiquitin transferase Ubiquitin carboxyl-terminal hydrolase A Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein	C7G034 P02889 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P54201 P54644 Q02720 Q1ZXD3 Q27562 Q27563 Q54BC6 Q54BC8 Q54CH3 Q54CI0 Q54DB2 Q54DM7 Q54HW1 Q54IF2 Q54JL7 Q54JM5 Q54LR6 Q54MG8 Q54NQ0 Q54PF1 Q54PJ1 Q54PN7 Q54QF1 Q54QR2 Q54S82 Q54TM9 Q54UB5 Q54UJ0 Q54WI8 Q54XM7 Q552Y8 Q553B4 Q553E0 Q556Q0 Q559F4 Q55BV5 Q55C75 Q55D66 Q55DY7 Q55FY4 Q55G04 Q55GJ6 Q86IJ1 Q86JA1 Q8T9S7 Q967U1	DDB_G0267906 DDB_G0272951 DDB_G0275865 DDB_G0281657 DDB_G0283983 DDB_G0285063 DDB_G0285967 DDB_G0286481 DDB_G0288795 DDB_G0292920 M4 akt casK cnrN csnk2b dagA dapA dpr1 pkbA prdD prdE prtC prtD psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 pteN ptenA sks1 tbp2 tbpB ubpA ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO usp5 veg116	Dictyostelium discoideum
Orc1 removal from chromatin	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 Cullin-2 Origin recognition complex subunit 1 Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RING-box protein 1 SCF ubiquitin ligase complex protein SKP1a SCF ubiquitin ligase complex protein SKP1b Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein	P02889 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P52285 Q1ZXD3 Q27562 Q27563 Q54BC6 Q54BC8 Q54CI0 Q54DB2 Q54DM7 Q54HW1 Q54JM5 Q54K33 Q54NQ0 Q54PJ1 Q54PN7 Q54QR2 Q54RM2 Q54S82 Q54UB5 Q54UJ0 Q54WI8 Q54XM7 Q552Y8 Q553E0 Q556Q0 Q557E4 Q559F4 Q55BV5 Q55C75 Q55D66 Q55DY7 Q55G04 Q55GJ6 Q86IJ1 Q86JA1 Q967U1 Q9XZJ3	DDB_G0272951 M4 cul2 culB dapA dpr1 fp21A fp21B fpa1 fpa1A fpa1B fpa2 fpaA fpaB-1 fpaB-2 orc1 orcA prdD prdE prtC prtD psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 rbx1 skp1A skp1B sks1 tbp2 tbpB ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116	Dictyostelium discoideum
Cam-PDE 1 activation	3',5'-cyclic-AMP phosphodiesterase 4 3',5'-cyclic-nucleotide phosphodiesterase regA Calmodulin-like protein Calmodulin Myosin-ID light chain cGMP-specific 3',5'-cGMP phosphodiesterase 3	B0G0Y8 O00897 P02599 Q23917 Q7Z2B8 Q86H13	Pde4 calA calB camA mlcD pde2 pde3 regA	Dictyostelium discoideum
DARPP-32 events	3',5'-cyclic-AMP phosphodiesterase 4 3',5'-cyclic-nucleotide phosphodiesterase regA cGMP-specific 3',5'-cGMP phosphodiesterase 3	B0G0Y8 Q23917 Q86H13	Pde4 pde2 pde3 regA	Dictyostelium discoideum
PDE3B signalling	3',5'-cyclic-AMP phosphodiesterase 4 3',5'-cyclic-nucleotide phosphodiesterase regA cGMP-specific 3',5'-cGMP phosphodiesterase 3	B0G0Y8 Q23917 Q86H13	Pde4 pde2 pde3 regA	Dictyostelium discoideum
G alpha (s) signalling events	3',5'-cyclic-AMP phosphodiesterase 4 3',5'-cyclic-nucleotide phosphodiesterase regA cGMP-specific 3',5'-cGMP phosphodiesterase 3	B0G0Y8 Q23917 Q86H13	Pde4 pde2 pde3 regA	Dictyostelium discoideum
cGMP effects	3',5'-cyclic-AMP phosphodiesterase 4 3',5'-cyclic-nucleotide phosphodiesterase regA cGMP-specific 3',5'-cGMP phosphodiesterase 3	B0G0Y8 Q23917 Q86H13	Pde4 pde2 pde3 regA	Dictyostelium discoideum
Cholesterol biosynthesis	3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 3beta-hydroxysteroid dehydrogenase Cycloartenol synthase Delta(14)-sterol reductase Diphosphomevalonate decarboxylase Farnesyl diphosphate synthase Geranylgeranyl pyrophosphate synthase Hydroxymethylglutaryl-CoA synthase B Isopentenyl-diphosphate Delta-isomerase Mevalonate kinase Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Probable acetyl-CoA acetyltransferase Probable lanosterol 14-alpha demethylase Protein arv1 homolog Putative methylsterol monooxygenase DDB_G0269788 Squalene monooxygenase Squalene synthase	P34135 Q1ZXH9 Q54BK1 Q54BK7 Q54DR1 Q54GD9 Q54PP1 Q54TU9 Q54UH9 Q54YQ9 Q55D54 Q55D85 Q86AD9 Q86AG7 Q86HL5 Q9NH02 Q9NH03	DDB_G0269788 DDB_G0271544 DDB_G0281069 DDB_G0281487 Dipi arv1 cas1 cyp51 erg24 fdfT fps ggps1 hgsB hmgA idi ipi mvd mvk sqle	Dictyostelium discoideum
Fatty acyl-CoA biosynthesis	3-oxoacyl-[acyl-carrier-protein] reductase Acetyl-CoA carboxylase Delta 9 fatty acid desaturase Delta 9 fatty acid desaturase MaoC-like domain-containing protein Palmitoyl-protein thioesterase 1 Palmitoyl-protein thioesterase 2 Probable ATP-citrate synthase Probable polyketide synthase 16 Probable polyketide synthase 17 Probable polyketide synthase 1	Q54IE5 Q54IE9 Q54J08 Q54N35 Q54T75 Q54YA0 Q556T4 Q55E72 Q55E82 Q869W9 Q869X2	DDB_G0269356 DDB_G0273105 DDB_G0281965 DDB_G0288801 accA acly pks1 pks16 pks17 ppt1 ppt2 stlA	Dictyostelium discoideum
Macroautophagy	5'-AMP-activated protein kinase subunit gamma 5'-AMP-activated serine/threonine-protein kinase catalytic subunit alpha Association with the SNF1 complex (ASC) domain-containing protein Autophagy protein 5 Autophagy-related protein 101 Autophagy-related protein 13 N-terminal domain-containing protein Autophagy-related protein 18 Autophagy-related protein 3 Autophagy-related protein 8-like protein DDB_G0290491 Autophagy-related protein 8 Autophagy-related protein 9 Beclin-1-like protein B Charged multivesicular body protein 2a homolog 2 Charged multivesicular body protein 3 Charged multivesicular body protein 4 Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cysteine protease atg4 Cysteine protease GTP-binding protein Rheb homolog Myotubularin phosphatase domain-containing protein Myotubularin phosphatase domain-containing protein Myotubularin phosphatase domain-containing protein Myotubularin-related protein DDB_G0290005 Myotubularin-related protein Phosphatidylinositol 3-kinase VPS34-like Probable serine/threonine-protein kinase MARK-B Probable serine/threonine-protein kinase pats1 Probable serine/threonine-protein kinase vps15 Protein LST8 homolog Protein raptor homolog Protein tipD Ragulator complex protein LAMTOR3 homolog Ragulator complex protein LAMTOR4 homolog Ragulator complex protein LAMTOR5 homolog Ras-related GTP-binding protein A Ras-related GTP-binding protein Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase atg1 Serine/threonine-protein kinase tor UV radiation resistance-associated gene protein Ubiquitin-like modifier-activating enzyme atg7 Ubiquitin-like protein atg12 Uncharacterized protein DDB_G0292160 Uncharacterized protein WD repeat domain phosphoinositide-interacting protein 3 phosphatidylinositol-3-phosphatase phosphatidylinositol-3-phosphatase phosphatidylinositol-3-phosphatase phosphatidylinositol-3-phosphatase	O15736 P54676 Q1ZXA8 Q1ZXD2 Q54C52 Q54D08 Q54DB1 Q54DY3 Q54F59 Q54G11 Q54GQ1 Q54GT9 Q54H00 Q54IK1 Q54J54 Q54JC5 Q54JI9 Q54KZ4 Q54MV2 Q54NA2 Q54NA3 Q54P63 Q54PK6 Q54PL3 Q54QM7 Q54QW5 Q54S77 Q54SA0 Q54TD5 Q54UG7 Q54YC2 Q54YF2 Q550A8 Q550Q4 Q557H7 Q55AZ2 Q55BR7 Q55BY0 Q55E04 Q55E58 Q55EE1 Q86C65 Q86CR6 Q86CR8 Q86CR9 Q86CS2 Q86H98 Q86J23 Q86K93 Q8T277	DDB_G0269162 DDB_G0269272 DDB_G0269448 DDB_G0271610 DDB_G0274833 DDB_G0278311 DDB_G0281845 DDB_G0283567 DDB_G0283753 DDB_G0284481 DDB_G0288175 DDB_G0288287 DDB_G0288731 DDB_G0289807 DDB_G0290005 DDB_G0290491 DDB_G0291948 DDB_G0292160 DDB_G0293258 ampka apg1 apg12 apg3 apg4-1 apg4-2 apg5 apg6B apg7 apg8 apg9 atg1 atg12 atg18 atg3 atg4-1 atg4-2 atg5 atg6B atg7 atg8 atg9 chmp2a2 chmp3 chmp4 chmp6 chmp7 lst8 mapbpip mrkB pats1 pik3r4 pik5 pikE prkaa prkab prkag ragA ragC raptor rheb snf7 snfA tipD tor vps15 vps20 vps24 vps2B vps32 wdr45l wipi2	Dictyostelium discoideum
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating Glucose-6-phosphate 1-dehydrogenase Probable 6-phosphogluconolactonase Probable phosphoglucomutase-2 Probable transaldolase Ribokinase Ribose-5-phosphate isomerase Ribulose-phosphate 3-epimerase	Q54CJ3 Q54UP4 Q54UQ2 Q54UQ4 Q54YE7 Q551C2 Q557D2 Q8TA03	PGD g6pd-1 g6pd-2 gnd pgl pgls pgmB rbsk rpe rpiA tal zwf	Dictyostelium discoideum	G31080DL

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