GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **360** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Adrenaline signalling through Alpha-2 adrenergic receptor	Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor	I3LFJ1 P18871 Q38PT0	A2AR ADRA2A ADRA2B ADRA2C	Sus scrofa (pig)
Dissolution of Fibrin Clot	Alpha-2-antiplasmin isoform X2 Annexin Histidine-rich glycoprotein Plasminogen activator inhibitor 1 Plasminogen activator inhibitor 1 Plasminogen activator inhibitor 2 Plasminogen Protein S100-A10 Serpin B6 Serpin B8 isoform a Serpin family E member 2 Tissue-type plasminogen activator Urokinase-type plasminogen activator	A0A286ZJV6 A0A286ZRF3 A0A287B9B3 A0A481B9A6 A0A5G2QXR3 A0A5K1UAD0 F1SMW7 F1SMX7 F1SU38 F2Z5M2 I3LQQ6 P79335 Q8SQ23	ANXA2 HRG PAI1 PLANH1 PLAT PLAU PLG S100A10 SERPINB2 SERPINB6 SERPINB8 SERPINE1 SERPINE2 SERPINF2	Sus scrofa (pig)
Sialic acid metabolism	Alpha-2,8-sialyltransferase 8B Alpha-2,8-sialyltransferase 8F Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Alpha2,3-sialyltransferase Beta-galactosidase Beta-galactoside alpha-2,6-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase CMP-sialic acid transporter isoform X1 Carboxypeptidase Gal-NAc6S Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Lactosylceramide alpha-2,3-sialyltransferase N-acetylneuraminate lyase N-acetylneuraminate lyase N-acetylneuraminate synthase N-acetylneuraminic acid phosphatase N-acylneuraminate cytidylyltransferase ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 Sialidase-1 Sialin Type 2 lactosamine alpha-2,3-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase beta-galactoside alpha-(2,6)-sialyltransferase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase	A0A286ZR19 A0A286ZSQ8 A0A286ZZR3 A0A287A0U5 A0A287A537 A0A287A8C8 A0A287ACU7 A0A287AMU7 A0A287ARB7 A0A287B0V1 A0A287BAR8 A0A287BJ72 A0A287BMG4 A0A287BP79 A0A287BS35 A0A480E8L5 A0A480LAY6 A0A8W4FH71 A0A8W4FIM2 A5PF10 F1RRV7 F1RS05 F1RWB6 F1RWP7 F1RZ66 F1S0G0 F1S6H2 F1SM45 F6PZ23 I3LGI9 I3LS82 M1FW61 Q70D54 Q9BEC7	CMAS CTSA GLB1 GNE NANP NANS NEU1 NEU2 NEU3 NEU4 NPL SLC17A5 SLC35A1 ST3GAL-III ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL1 ST6GAL2 ST6GALNAC1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA2 ST8SIA3 ST8SIA4 ST8SIA5 ST8SIA6 ST8Sia 2	Sus scrofa (pig)
Adrenoceptors	Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor Beta-3 adrenergic receptor	A0A2C9F3F6 A7BJW1 F1RR36 F1S5H5 F1S8D0 I3LFJ1 P18871 Q38PT0 Q95252 Q9TSW7 Q9TTM9	A2AR ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 BAR3 alpha-1A	Sus scrofa (pig)
O-linked glycosylation of mucins	Alpha-1,4-N-acetylglucosaminyltransferase Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase C1GALT1-specific chaperone 1 Glucosaminyl (N-acetyl) transferase 4 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Mucin 13, cell surface associated Mucin 15, cell surface associated Mucin 2, oligomeric mucus/gel-forming Mucin 20, cell surface associated Mucin 4, cell surface associated Mucin 5AC, oligomeric mucus/gel-forming Mucin 5B, oligomeric mucus/gel-forming Mucin 6, oligomeric mucus/gel-forming Mucin-1 Polypeptide N-acetylgalactosaminyltransferase like 5 Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase SEA domain-containing protein Sulfotransferase UDP-GlcNAc	A0A1S6M251 A0A286ZLM1 A0A286ZNW2 A0A287A1R2 A0A287A6N0 A0A287A7J0 A0A287AIU3 A0A287ASH2 A0A287B5M2 A0A287B5N4 A0A287BKI9 A0A5G2QU42 A0A5G2R0V1 A0A5G2R1K9 A0A5G2R9D7 A0A8W4FAW4 A0A8W4FBP7 A0A8W4FES6 A0A8W4FM62 A5GFW8 F1RGR9 F1RIZ9 F1RJJ7 F1RQC2 F1RUC2 F1S070 F1S2M2 F1S3D0 F1S3Y5 F1S4B7 F1S6W6 F1SAI6 F1SFZ5 F1SIN0 F1SIW5 F1SQ58 F1SSE9 F1SSN3 F6Q8N2 I3LAJ3 I3LCH7 I3LFY2 I3LK83 I3LSM2 Q864U8	A4GNT B3GNT2 B3GNT4 B3GNT5 B3GNT6 B3GNT7 B3GNT8 B3GNT9 B3GNTL1 B4GALT5 B4GALT6 C1GALT1 C1GALT1C1 CHST4 GALNT1 GALNT10 GALNT11 GALNT12 GALNT14 GALNT15 GALNT16 GALNT17 GALNT18 GALNT2 GALNT4 GALNT5 GALNT6 GALNT7 GALNT8 GALNT9 GALNTL5 GCNT1 GCNT3 GCNT4 GCNT7 MUC1 MUC13 MUC15 MUC2 MUC20 MUC4 MUC5AC MUC5B MUC6	Sus scrofa (pig)
Glycogen breakdown (glycogenolysis)	Alpha-1,4 glucan phosphorylase Alpha-1,4 glucan phosphorylase Calmodulin 3 Lysosomal alpha-glucosidase Phosphorylase b kinase regulatory subunit Phosphorylase b kinase regulatory subunit Phosphorylase b kinase regulatory subunit glycogenin glucosyltransferase glycogenin glucosyltransferase phosphorylase kinase	A0A286ZUI9 A0A287AGE8 A0A287AL94 A0A287B6P0 A0A287BBS7 A0A5G2QWK6 A0A5G2RE07 F1RG75 F1RPM0 F1RZ82	CALM3 GAA GYG1 GYG2 PHKA1 PHKA2 PHKB PHKG2 PYGL PYGM	Sus scrofa (pig)	G58161NS
N-Glycan antennae elongation	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C Alpha-2,8-sialyltransferase 8B Alpha-2,8-sialyltransferase 8F Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4 MGAT4 family member C ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 beta-galactoside alpha-(2,6)-sialyltransferase	A0A1S6M251 A0A286ZSQ8 A0A286ZZR3 A0A287AS89 A0A287B0E4 A0A287BG16 A0A287BJP1 A0A5G2QU42 F1RWB6 F1S1A6 F1S444 F1S6H2 F1SPA3 M1FW61 Q6ITT3	B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT5 B4GALT6 MGAT4A MGAT4B MGAT4C ST3GAL4 ST6GAL1 ST8SIA2 ST8SIA3 ST8SIA6 ST8Sia 2	Sus scrofa (pig)	G81533KY
N-glycan trimming and elongation in the cis-Golgi	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Glycoprotein endo-alpha-1,2-mannosidase	A0A287B4B5 Q0KKC2	MANEA MGAT1	Sus scrofa (pig)	G58161NS
Reactions specific to the complex N-glycan synthesis pathway	Alpha-(1,6)-fucosyltransferase Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-L-fucosidase Alpha-mannosidase Alpha-mannosidase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Fucosyltransferase Glycoprotein hormones alpha chain Lutropin subunit beta	A0A286ZI43 A0A287A2S8 A0A287ACZ4 A0A5G2QG83 A0A5G2RDR7 F1SA54 F1SBU3 I3LNS9 P01219 P01232	CGA CHST10 CHST8 FUCA1 FUT8 LHB LOC100513844 MAN2A1 MAN2A2 MGAT2	Sus scrofa (pig)	G70323CJ G82576YO
Lewis blood group biosynthesis	Alpha-(1,3)-fucosyltransferase Alpha-(1,3)-fucosyltransferase Alpha2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4 Fucosyltransferase Fucosyltransferase Fucosyltransferase Galactoside alpha-(1,2)-fucosyltransferase 2 Glycosyltransferase 2-like domain-containing protein Hexosyltransferase Hexosyltransferase Hexosyltransferase ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Type 2 lactosamine alpha-2,3-sialyltransferase	A0A287AMU7 A0A287B633 A0A287B819 A0A287BIT3 A0A287BS10 A0A8W4FN42 F1RS05 F1RZT4 F1S6H2 F1SAB1 F1SBU3 I3L7N4 Q10982 Q70D54	B3GALT1 B3GALT2 B3GALT4 FUT10 FUT11 FUT2 FUT4 FUT7 LOC100513844 LOC110255214 ST3GAL-III ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6	Sus scrofa (pig)	G39211DH G81971FM G83633HB G90387AM G98173LG
Digestion	Alkaline phosphatase Guanylate cyclase activator 2B Guanylin Guanylyl cyclase C Pirin	A0A287AF84 K7GKW6 O13009 P55204 P79897	GUC2C GUCA2 GUCA2A GUCA2B GUCY2C LOC100522404 PIR	Sus scrofa (pig)
Fructose biosynthesis	Aldo-keto reductase family 1 member B1 Sorbitol dehydrogenase	A0A287AT21 A0A5G2R274	AKR1B1 SORD	Sus scrofa (pig)	G58161NS
Phase I - Functionalization of compounds	Aldehyde dehydrogenase Amine oxidase Amine oxidase Amine oxidase Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Arylacetamide deacetylase Biphenyl hydrolase like Carbonyl reductase (NADPH) Carboxylesterase 1 Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxymethylenebutenolidase homolog Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 family 2 subfamily B member 6B Cytochrome b5 type B Diamine oxidase [copper-containing] Epoxide hydrolase 1 Epoxide hydrolase Mitochondrial amidoxime reducing component 2 Mitochondrial amidoxime-reducing component 1 N-ribosyldihydronicotinamide NADH-cytochrome b5 reductase	A0A286ZIQ2 A0A286ZKL1 A0A286ZPA0 A0A287A6V9 A0A287A8N2 A0A287ALY1 A0A287AXR4 A0A287B6R1 A0A287B7I8 A0A2C9F385 A0A480K1W5 A0A5G2QPB6 A0A5G2QRH6 A0A5G2QSC0 A0A5G2QWJ0 A0A5G2RD43 A0A5G2REZ9 F1RF16 F1RWY7 F1S1G7 F1S9I9 F1SDC4 F1SGX4 I3LA57 I3LEX8 I3LF82 P79381 Q9TRC7	AADAC ABP AHR AHRR ALDH3A1 AOC1 AOC2 ARNT ARNT2 BPHL CBR3 CES1 CES3 CMBL CYB5B CYB5R3 CYP2B6B CYP3A22 CYP3A227 CYP3A29 DAO EPHX1 LOC100520329 LOC100736962 LOC110256000 MTARC1 MTARC2 NQO2	Sus scrofa (pig)
RND1 GTPase cycle	Aldehyde dehydrogenase family 3 member A2 Carboxypeptidase D Caveolin Coiled-coil domain containing 88A DEP domain containing 1B Desmoplakin Discs large MAGUK scaffold protein 5 Dystonin Epithelial stromal interaction 1 Family with sequence similarity 135 member A Family with sequence similarity 83 member B Fibroblast growth factor receptor substrate 3 Flotillin Growth factor receptor bound protein 7 Kinase D interacting substrate 220 Mucin 13, cell surface associated Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Plakophilin 4 Pleckstrin homology and RhoGEF domain containing G5 Plexin A1 RAS protein activator like 2 RNA binding motif protein 39 Ras-related protein R-Ras2 Rho GTPase activating protein 5 Rho GTPase-activating protein 35 Thioredoxin like 1 Transferrin receptor protein 1 Transferrin receptor protein 1 Transmembrane protein 59 Tyrosine-protein phosphatase non-receptor type 13 UBX domain protein 11 Uncharacterized protein Vang-like protein Vang-like protein receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A286ZJQ9 A0A286ZM17 A0A286ZPP2 A0A286ZSG6 A0A287A328 A0A287A6D8 A0A287AH84 A0A287AIV8 A0A287ALN0 A0A287B7U3 A0A287BAQ0 A0A287BBJ7 A0A287BCT3 A0A287BF82 A0A287BKB6 A0A480JZF5 A0A5G2QA45 A0A5G2R4N6 A0A5S6GXI4 F1RJY3 F1RM07 F1RN68 F1RTT1 F1RUW8 F1RW75 F1RX94 F1RZW2 F1S1X9 F1S916 F1SAW7 F1SKR9 F1SQ58 F1SUT8 I3LD06 I3LMD8 Q2F7Z7 Q8HZV3	ALDH3A2 ARHGAP35 ARHGAP5 CAV1 CCDC88A CPD DEPDC1B DLG5 DSP DST EPHA2 EPSTI1 FAM135A FAM83B FLOT2 FRS3 GRB7 KIDINS220 LOC100516390 MUC13 PIK3R1 PIK3R2 PKP4 PLEKHG5 PLXNA1 PTPN13 RASAL2 RBM39 RRAS2 TFRC TMEM59 TXNL1 UBXN11 VANGL1 VANGL2 WDR6	Sus scrofa (pig)
RND2 GTPase cycle	Aldehyde dehydrogenase family 3 member A2 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 Bridge-like lipid transfer protein family member 3B Caveolin Cytoskeleton associated protein 4 DEP domain containing 1B Desmoglein 1 Desmoglein-1 Discs large MAGUK scaffold protein 5 Dystonin Family with sequence similarity 83 member B Fibroblast growth factor receptor substrate 3 Formin binding protein 1 Golgin A3 Kinase D interacting substrate 220 Kinectin 1 Leucine rich repeat containing 1 Mucin 13, cell surface associated Nischarin Nuclear migration protein nudC Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Plakophilin 4 Plexin D1 RNA binding motif protein 39 Rho GTPase activating protein 1 Rho GTPase activating protein 5 Rho GTPase-activating protein 35 Rho family GTPase 2 Scribble planar cell polarity protein Thioredoxin like 1 Transferrin receptor protein 1 Transferrin receptor protein 1 Tyrosine-protein phosphatase non-receptor type 13 UBX domain protein 11 Uncharacterized protein Vang-like protein Vang-like protein receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A286ZJQ9 A0A286ZPP2 A0A287ABR1 A0A287AH84 A0A287AIV8 A0A287AZG0 A0A287B8R2 A0A287BAQ0 A0A287BBJ7 A0A287BCT3 A0A287BF82 A0A287BKB6 A0A287BQA2 A0A480JZF5 A0A5G2QA45 A0A5G2QWP0 A0A5G2RKR1 A0A5S6GXI4 A0A8W4FAC1 A0A8W4FQG7 F1RI72 F1RJY3 F1RM07 F1RUW8 F1RZV9 F1RZW2 F1S1X9 F1S916 F1SAW7 F1SKR9 F1SPP8 F1SQ58 F1SSN5 F1SUT8 I3LA65 I3LD06 I3LM60 I3LMD8 I3LQJ8 Q3BDI7 Q8HZV3	ALDH3A2 ARHGAP1 ARHGAP35 ARHGAP5 BLTP3B CAV1 CKAP4 DEPDC1B DLG5 DSG1 DST EPHA2 FAM83B FNBP1 FRS3 GOLGA3 KCTD13 KIDINS220 KTN1 LOC100516390 LRRC1 MUC13 NISCH NUDC PIK3R1 PIK3R2 PKP4 PLXND1 PTPN13 RBM39 RND2 SCRIB TFRC TNFAIP1 TXNL1 UBXN11 VANGL1 VANGL2 WDR6	Sus scrofa (pig)
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Aldehyde dehydrogenase family 3 member A2 Amyloid-beta A4 protein Amyloid-beta precursor protein Cytochrome b5 E2 ubiquitin-conjugating enzyme Emerin Heme oxygenase 1 Major prion protein Protein transport protein Sec61 subunit gamma SEC61 translocon subunit beta Small glutamine rich tetratricopeptide repeat co-chaperone alpha Stress-associated endoplasmic reticulum protein Syntaxin-1A Vesicle-associated membrane protein 2 Vesicle-associated membrane protein-associated protein A	A0A0U2ETD0 A0A286ZIJ7 A0A286ZTE6 A0A287B1B1 A0A287BBJ7 A0A5G2QDR3 A0A5G2QXK3 A0A5G2R276 A0A5G2RB73 F1RGA3 F2Z5P0 P00172 P32394 P49927 P79307	A4 AD1 ALDH3A2 APP CYB5 CYB5A EMD HMOX1 PRNP PRP SEC61B SEC61G SERP1 SGTA STX1A UBE2J2 VAMP2 VAPA	Sus scrofa (pig)
Sphingolipid catabolism	Aldehyde dehydrogenase family 3 member A2 Aldehyde dehydrogenase Aldehyde dehydrogenase Alkaline ceramidase Alkaline ceramidase Alkaline ceramidase Phospholipid phosphatase 1 Phospholipid phosphatase 3 Sphingosine-1-phosphate phosphatase 1 Sphingosine-1-phosphate phosphatase 2 sphinganine-1-phosphate aldolase	A0A287A341 A0A287ABN3 A0A287BBJ7 A0A287BEZ7 A0A287BQZ5 A0A5G2QIU3 A0A5G2R1U7 I3L5T1 I6L6E1 P60588 V9GZ89	ACER1 ACER2 ACER3 ALDH3A2 ALDH3B1 ALDH3B2 LPP1 PLPP1 PLPP3 PPAP2A SGPL1 SGPP1 SGPP2	Sus scrofa (pig)
Ciprofloxacin ADME	Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Solute carrier family 22 member 1 Solute carrier organic anion transporter family member	A0A287A9U9 A0A287BAY9 A0A5K1U410 A0A5S6GWJ4 Q8MIB3	ABCG2 ABCG2A ALB BMDP SLC22A1 SLCO1A2	Sus scrofa (pig)
Scavenging of heme from plasma	Albumin Apolipoprotein A-I Apolipoprotein L3 isoform 1 Apolipoprotein L3 isoform X1 CD163 molecule Globin domain-containing protein Haptoglobin Hemoglobin, beta Hemopexin Ig lambda chain C region Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin V-set domain-containing protein Protein AMBP Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A075B7I6 A0A0A0MY58 A0A286ZIM1 A0A286ZKR7 A0A286ZLN6 A0A286ZMU4 A0A286ZP42 A0A286ZQC7 A0A286ZQH2 A0A286ZSX6 A0A286ZU07 A0A286ZUL8 A0A287A3T6 A0A287A7S8 A0A287AA42 A0A287ADE7 A0A287AE51 A0A287AKW2 A0A287ALJ6 A0A287AM45 A0A287AM58 A0A287ANU5 A0A287AP28 A0A287APG4 A0A287AU93 A0A287AUR4 A0A287AWH3 A0A287AWQ8 A0A287AYC4 A0A287B1Y4 A0A287B5G0 A0A287B9P2 A0A287BAB3 A0A287BAY9 A0A287BDV3 A0A287BH28 A0A287BHK5 A0A287BHU3 A0A287BLH9 A0A287BMT4 A0A287BNX9 A0A287BRE1 A0A5G2NLY0 A0A5G2Q7F8 A0A5G2Q7Q6 A0A5G2QRW3 A0A5G2R9V1 A0A5G2RC04 A0A8W4F6L3 A0A8W4F7N5 A0A8W4F807 A0A8W4F9I3 A0A8W4FA34 A0A8W4FAN5 A0A8W4FC14 A0A8W4FC67 A0A8W4FDG3 A0A8W4FEK6 A0A8W4FEL9 A0A8W4FGI9 A0A8W4FGK7 A0A8W4FHQ3 A0A8W4FHY5 A0A8W4FI53 A0A8W4FJL3 A0A8W4FLJ3 A0A8W4FMG3 A0A8W4FMI6 A0A8W4FN37 A0A8W4FNE8 A0A8W4FQ38 A0A8W4FQC5 F1RGX4 F1RL06 F1RMN7 F1S9H7 F1SPU1 F1STC2 F1STC3 F1STC5 I3L6U3 I3LBK0 P01846 Q8SPS7	ALB AMBP APOA1 CD163 HBB HP HPX IGKV5-2 LOC100125542 LOC100156062 LOC100523213 LOC106510284 LOC110259958	Sus scrofa (pig)
HS-GAG biosynthesis	Agrin Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 Exostosin glycosyltransferase 1 Exostosin glycosyltransferase 2 Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Glypican-6 Heparan sulfate 2-O-sulfotransferase 1 Heparan-sulfate 6-O-sulfotransferase Heparan-sulfate 6-O-sulfotransferase Heparan-sulfate 6-O-sulfotransferase Solute carrier family 35 member D2 Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Syndecan-4 Syndecan Syndecan Syndecan [heparan sulfate]-glucosamine N-sulfotransferase [heparan sulfate]-glucosamine N-sulfotransferase [heparan sulfate]-glucosamine N-sulfotransferase	A0A286ZS39 A0A287A1I4 A0A287A8H4 A0A287AC51 A0A287AE96 A0A287AF31 A0A287AJ15 A0A287ATH4 A0A287ATW7 A0A287B0C5 A0A287B286 A0A287BFE7 A0A287BFJ7 A0A480K0L3 A0A5G2QNB9 F1RNM8 F1RP49 F1RTE1 F1RZK7 F1S0L5 F1S152 F1S274 I3LAM6 I3LAX8 I3LHH5 K7GNF5 K7GQ93 M3V841 Q8HZJ6	AGRN EXT1 EXT2 GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 HS2ST1 HS3ST1 HS3ST2 HS3ST3A1 HS3ST3B1 HS3ST4 HS3ST5 HS3ST6 HS6ST1 HS6ST2 HS6ST3 NDST1 NDST2 NDST3 NDST4 SDC1 SDC2 SDC3 SDC4 SLC35D2	Sus scrofa (pig)
A tetrasaccharide linker sequence is required for GAG synthesis	Agrin Beta-1,4-galactosyltransferase Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Glypican-6 Hexosyltransferase Neurocan Syndecan-4 Syndecan Syndecan Syndecan Versican core protein Xylosyltransferase 1 Xylosyltransferase 2	A0A286ZNW5 A0A286ZS39 A0A286ZTI9 A0A287AHN9 A0A287AIY6 A0A287AJ15 A0A287ATH4 A0A287B286 A0A480K0L3 A0A5G2RB02 A0A5K1UKC5 A0A8W4FKJ8 F1REZ2 F1RLT2 F1RNM8 F1RT78 F1RTE1 F1S0L5 F1SJ86 I3LK23 I3LR31 I3LU42 K7GNF5 K7GQ93 Q8HZJ6	AGRN B3GALT6 B3GAT1 B3GAT2 B3GAT3 B4GALT7 BCAN BGN CSPG4 CSPG5 DCN GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 NCAN SDC1 SDC2 SDC3 SDC4 VCAN XYLT1 XYLT2	Sus scrofa (pig)
HS-GAG degradation	Agrin Alpha-L-iduronidase Beta-galactosidase Beta-galactosidase Beta-galactosidase Beta-glucuronidase Galactosidase beta 1 like Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Glypican-6 Heparanase 2 (inactive) Heparanase Iduronate 2-sulfatase N-acetyl-alpha-glucosaminidase N-sulfoglucosamine sulfohydrolase Syndecan-4 Syndecan Syndecan Syndecan	A0A286ZS39 A0A287AJ15 A0A287ATH4 A0A287B239 A0A287B286 A0A287BS38 A0A480K0L3 A0A5G2QG63 A0A5G2QHV1 A0A5G2R907 F1RNM8 F1RTE1 F1RZ89 F1S0L5 F1S8W7 F1SR82 I3LGI9 K7GNF5 K7GQ93 M3VHA3 Q4FAT7 Q8HZJ6	AGRN GLB1 GLB1L GLB1L2 GLB1L3 GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 GUSB HPSE HPSE2 IDS IDUA NAGLU SDC1 SDC2 SDC3 SDC4 SGSH	Sus scrofa (pig)	G01550VL G09546QO
Retinoid metabolism and transport	Agrin Aldo-keto reductase family 1 member C1 Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein B Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Apolipoprotein M Beta-carotene oxygenase 1 Carotenoid-cleaving dioxygenase, mitochondrial Colipase Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Glypican-6 LDL receptor related protein 10 LDL receptor related protein 12 LDL receptor related protein 8 Lecithin retinol acyltransferase Lipoprotein lipase Phospholipase B1, membrane-associated Putative aldo-keto reductase family 1 member C2 Retinol binding protein 1 Retinol binding protein 2 Retinol dehydrogenase 11 Retinol-binding protein Syndecan-4 Syndecan Syndecan Syndecan Transthyretin Transthyretin Triacylglycerol lipase	A0A286ZPB0 A0A286ZQC7 A0A286ZS39 A0A286ZXB4 A0A287AG13 A0A287AJ15 A0A287ATH4 A0A287AW22 A0A287B0A0 A0A287B286 A0A287BCU5 A0A287BM29 A0A480K0L3 A0A480KVF0 A0A480YJR0 A0A481BCM9 A0A5G2QEH1 A0A5G2QIE9 A0A5G2QTV7 A0A5G2RI58 A0A5G2RJR8 E7CXS0 F1RM45 F1RNM8 F1RTE1 F1RYR6 F1S0L5 F1SA24 F1SC80 F6PSJ3 K7GNF5 K7GQ93 P02703 P27917 P50390 Q2LE37 Q8HZJ6	AGRN AKR1C1 AKR1C2 APOA1 APOA2 APOA4 APOB APOC2 APOC3 APOE APOM ApoER2 BCO1 BCO2 CLPS GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 LPL LRAT LRP10 LRP12 LRP8 PLB1 PNLIP RBP1 RBP2 RBP4 RDH11 SDC1 SDC2 SDC3 SDC4 TTR	Sus scrofa (pig)
Keratan sulfate degradation	Aggrecan core protein Beta-galactosidase Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Beta-hexosaminidase Fibromodulin Galactosidase beta 1 like Keratocan Lumican Mimecan N-acetylglucosamine-6-sulfatase Osteomodulin Prolargin	A0A0H5ANC0 A0A287A524 A0A287A7V3 A0A287B239 A0A287B863 A0A5G2R907 D0G6X8 F1S6B4 F1S6B5 F1SQ08 F1SQ09 F1SR82 F1SUE2 I3LGI9	ACAN FMOD GLB1 GLB1L GLB1L2 GLB1L3 GNS HEXA HEXB KERA LUM OGN OMD PRELP	Sus scrofa (pig)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
Keratan sulfate biosynthesis	Aggrecan core protein Alpha2,3-sialyltransferase Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-glucuronyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4 Fibromodulin Gal-NAc6S Hexosyltransferase Hexosyltransferase Hexosyltransferase Keratocan Lumican Mimecan Osteomodulin Prolargin Solute carrier family 35 member D2 Sulfotransferase Sulfotransferase Sulfotransferase Type 2 lactosamine alpha-2,3-sialyltransferase	A0A0H5ANC0 A0A1S6M251 A0A287A537 A0A287AMU7 A0A287B863 A0A287BFE7 A0A287BG16 A0A287BJP1 A0A287BKI9 A0A5G2QU42 F1RRV7 F1RUS9 F1S1A6 F1S454 F1S6B4 F1S6B5 F1S6H2 F1SHJ6 F1SIW5 F1SPA3 F1SQ08 F1SQ09 F1SUE2 I3L6A5 I3LK83 Q70D54	ACAN B3GNT2 B3GNT4 B3GNT7 B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT5 B4GALT6 B4GAT1 CHST1 CHST2 FMOD KERA LOC100522551 LUM OGN OMD PRELP SLC35D2 ST3GAL-III ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL6	Sus scrofa (pig)

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