GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **276 - 300** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Platelet Aggregation (Plug Formation)	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Glycoprotein V platelet Prothrombin von Willebrand factor	B7TY21 B7TY22 F1SIB1 F1SL22 K7GN20	F2 GP1BB GP5 GP9 GPIX GPIbB VWF	Sus scrofa (pig)
Arachidonic acid metabolism	Fatty-acid amide hydrolase 1 fatty acid amide hydrolase	A0A287B2N9 Q9TUI8	FAAH FAAH1	Sus scrofa (pig)
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) Ficolin (collagen/fibrinogen domain containing) 1 MBL associated serine protease 1 MBL associated serine protease 2	A0A5G2QE59 A0A5G2QP75 A0A8W4FNY0 K7GKU8	FCN1 FCN2 MASP1 MASP2	Sus scrofa (pig)	G49108TO G57321FI
GDP-fucose biosynthesis	Fucose kinase GDP-L-fucose synthase GDP-mannose 4,6-dehydratase L-fucose mutarotase Solute carrier family 35 member C1	A0A287A769 A0A5G2QJW6 A0A5G2QRL7 A0A5G2R675 F1SAC0	FCSK FUOM GFUS GMDS SLC35C1	Sus scrofa (pig)	G85196CF G96881BQ
PI3K Cascade	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Klotho beta Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Toll-like receptor 9 Tyrosine-protein phosphatase non-receptor type non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287B630 A0A287B726 A0A287B929 A0A287BG34 A0A287BGK8 A0A287BHR8 A0A480ECT1 A0A480LMF4 A0A5G2QUY7 A0A5G2R7G2 A0A5K1UB41 A0A8X9AEI7 B6E241 F1RM38 F1RSR6 F1RY78 F1RY80 F1S3B8 F1S916 F1SAI0 F1SET9 F1SKR9 F1SMG2 I3L560 I3LLF1 I3LR27 K7GMT0 K7GQJ1 Q5I2M3 Q95L12	FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FGFR4 FLT3 FLT3LG Fgf4 GAB1 GAB2 GRB2 IRS1 IRS2 KL KLB PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 PIK3R4 PTPN11 TLR9	Sus scrofa (pig)
Downstream signaling of activated FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 1 Fibronectin leucine rich transmembrane protein 2 Fibronectin leucine rich transmembrane protein 3 Klotho Multifunctional fusion protein	A0A286ZV27 A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287BG34 A0A287BGK8 A0A5G2R7G2 F1RM38 F1RPZ1 F1RSR6 F1RY78 F1RY80 F1SBJ0 F1SET9 F1SMG2 K7GQJ1 Q95L12	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FLRT1 FLRT2 FLRT3 Fgf4 KL	Sus scrofa (pig)
FRS-mediated FGFR1 signaling	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A286ZUQ0 A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287BG34 A0A287BGK8 A0A480LMF4 A0A5G2QLX0 A0A5G2R7G2 B6E241 F1RM38 F1RSR6 F1RUW8 F1RY78 F1RY80 F1SET9 F1SMG2 I3LCQ9 K7GQJ1 Q2MJK3 Q95L12	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FRS3 Fgf4 GRB2 HRAS KL KRAS NRAS PTPN11 SOS1	Sus scrofa (pig)
PI-3K cascade:FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287BG34 A0A287BGK8 A0A480LMF4 A0A5G2R7G2 A0A5K1UB41 B6E241 F1RM38 F1RSR6 F1RY78 F1RY80 F1SET9 F1SKR9 F1SMG2 K7GMT0 K7GQJ1 Q95L12	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 Fgf4 GAB1 GRB2 KL PIK3CA PIK3R1 PTPN11	Sus scrofa (pig)
SHC-mediated cascade:FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZUQ0 A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287BG34 A0A287BGK8 A0A5G2QLX0 A0A5G2R7G2 A0A5K1V5Y3 B6E241 F1RM38 F1RSR6 F1RY78 F1RY80 F1SET9 F1SMG2 I3LCQ9 K7GQJ1 Q2MJK3 Q95L12	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 Fgf4 GRB2 HRAS KL KRAS NRAS SHC1 SOS1	Sus scrofa (pig)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Multifunctional fusion protein	A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287BG34 A0A287BGK8 A0A5G2R7G2 F1RM38 F1RSR6 F1RY78 F1RY80 F1SDV6 F1SET9 F1SMG2 K7GQJ1 Q95L12	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 Fgf4 KL PLCG1	Sus scrofa (pig)
FGFR1b ligand binding and activation	Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Transforming growth factor beta receptor 3	A0A287BG34 A0A287BGK8 A0A287BPI7 F1RM38 F1RY78 F1SMG2 K7GQJ1	FGF1 FGF10 FGF2 FGF22 FGF3 FGFR1 TGFBR3	Sus scrofa (pig)
FRS-mediated FGFR4 signaling	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho beta Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A286ZUQ0 A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287BGK8 A0A480LMF4 A0A5G2QLX0 A0A5G2QUY7 A0A5G2R7G2 B6E241 F1RM38 F1RUW8 F1RY80 F1S3B8 F1SET9 I3L560 I3LCQ9 I3LR27 Q2MJK3 Q95L12	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 FRS3 Fgf4 GRB2 HRAS KLB KRAS NRAS PTPN11 SOS1	Sus scrofa (pig)
PI-3K cascade:FGFR4	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Klotho beta Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287BGK8 A0A480LMF4 A0A5G2QUY7 A0A5G2R7G2 A0A5K1UB41 B6E241 F1RM38 F1RY80 F1S3B8 F1SET9 F1SKR9 I3L560 I3LR27 K7GMT0 Q95L12	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 Fgf4 GAB1 GRB2 KLB PIK3CA PIK3R1 PTPN11	Sus scrofa (pig)
SHC-mediated cascade:FGFR4	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho beta Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZUQ0 A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287BGK8 A0A5G2QLX0 A0A5G2QUY7 A0A5G2R7G2 A0A5K1V5Y3 B6E241 F1RM38 F1RY80 F1S3B8 F1SET9 I3L560 I3LCQ9 I3LR27 Q2MJK3 Q95L12	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 Fgf4 GRB2 HRAS KLB KRAS NRAS SHC1 SOS1	Sus scrofa (pig)
Phospholipase C-mediated cascade; FGFR4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho beta Multifunctional fusion protein	A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287BGK8 A0A5G2QUY7 A0A5G2R7G2 F1RM38 F1RY80 F1S3B8 F1SDV6 F1SET9 I3L560 I3LR27 Q95L12	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 Fgf4 KLB PLCG1	Sus scrofa (pig)
FGFR4 ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein	A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287BGK8 A0A5G2QUY7 A0A5G2R7G2 F1RM38 F1RY80 F1S3B8 F1SET9 I3LR27 Q95L12	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 Fgf4	Sus scrofa (pig)
Syndecan interactions	Fibroblast growth factor Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 2 Integrin subunit alpha 6 Integrin subunit alpha V Protein kinase C Syndecan-4 Syndecan Syndecan Syndecan Transforming growth factor beta-1 proprotein Vitronectin	A0A287AZ66 A0A287B286 A0A287BGK8 A0A5G2QY83 A0A5G2R7K7 A0A5K1V6L8 A0A8W4FC88 F1RV14 F1S0L5 F1SMF4 K7GNF5 K7GQ83 P07200 P48819 Q8HZJ6	FGF2 ITGA2 ITGA6 ITGAV ITGB1 ITGB3 ITGB4 ITGB5 PRKCA SDC1 SDC2 SDC3 SDC4 TGFB1 VTN	Sus scrofa (pig)
Cellular hexose transport	Fibroblast growth factor Major facilitator superfamily domain containing 4B Sodium/glucose cotransporter 1 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2 member 11 Solute carrier family 2 member 6 Solute carrier family 2 member 7 Solute carrier family 2 member 8 Solute carrier family 2 member 9 Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 45 member 3 Solute carrier family 5 member 2 Solute carrier family 5 member 4 Solute carrier family 5 member 9 Sugar transporter SWEET	A0A286ZVH1 A0A287AF62 A0A287AYR1 A0A287BJ50 A0A480HHY7 A0A5G2Q9A3 A0A5G2QCF1 A0A5G2R5M2 A0A8W4FPK7 C6JWG4 F1RF44 F1RGR5 F1RIH9 F1RLV1 F1RZP2 F1SB19 I3LQQ9 O62786 O62787 P20303 P31636	FGF21 GLUT1 GLUT2 GLUT3 MFSD4B SAAT1 SGLT3 SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A2 SLC2A3 SLC2A4 SLC2A6 SLC2A7 SLC2A8 SLC2A9 SLC45A3 SLC50A1 SLC5A1 SLC5A10 SLC5A2 SLC5A4 SLC5A9	Sus scrofa (pig)	G58161NS G70323CJ
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor receptor Klotho	A0A287AXR0 F1RSR6 K7GQJ1	FGF23 FGFR1 KL	Sus scrofa (pig)
RIPK1-mediated regulated necrosis	Flotillin-1 Flotillin Mixed lineage kinase domain like pseudokinase Programmed cell death 6 interacting protein Receptor interacting serine/threonine kinase 1 Syndecan binding protein non-specific serine/threonine protein kinase	A0A287AG10 A0A287AH24 A0A287ALN0 A0A287BRT1 A0A5G2R6P0 F1SGQ6 Q767L6	FLOT1 FLOT2 MLKL PDCD6IP RIPK1 RIPK3 SDCBP	Sus scrofa (pig)
FMO oxidises nucleophiles	Dimethylaniline monooxygenase [N-oxide-forming] 3 Flavin-containing monooxygenase 1 Flavin-containing monooxygenase	F1S6B6 I3LS94 P16549	FMO-1 FMO1 FMO2 FMO3	Sus scrofa (pig)
Extracellular matrix organization	Fibronectin	F1SS24	FN1	Sus scrofa (pig)
Antagonism of Activin by Follistatin	Follistatin Follistatin Inhibin beta A chain Inhibin beta B chain	A0A287BPF5 F1SLQ4 P03970 P10669	FST INHBA INHBB	Sus scrofa (pig)
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2	Q10982 Q29043	FUT1 FUT2	Sus scrofa (pig)
PECAM1 interactions	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Integrin beta Integrin subunit alpha V Platelet and endothelial cell adhesion molecule 1 Platelet endothelial cell adhesion molecule Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase	A0A287ABR0 A0A480LMF4 A0A5G2QU81 A0A5G2R7K7 A0A5K1V6L8 A1Y2K1 F1RT53 F1SDV6 F1SV94 K7GPR7 K7GS31 Q95242	FYN INPP5D ITGAV ITGB3 LCK LYN PECAM1 PLCG1 PTPN11 SRC YES1	Sus scrofa (pig)

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