GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **360** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
A tetrasaccharide linker sequence is required for GAG synthesis	Agrin Beta-1,4-galactosyltransferase Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Glypican-6 Hexosyltransferase Neurocan Syndecan-4 Syndecan Syndecan Syndecan Versican core protein Xylosyltransferase 1 Xylosyltransferase 2	A0A286ZNW5 A0A286ZS39 A0A286ZTI9 A0A287AHN9 A0A287AIY6 A0A287AJ15 A0A287ATH4 A0A287B286 A0A480K0L3 A0A5G2RB02 A0A5K1UKC5 A0A8W4FKJ8 F1REZ2 F1RLT2 F1RNM8 F1RT78 F1RTE1 F1S0L5 F1SJ86 I3LK23 I3LR31 I3LU42 K7GNF5 K7GQ93 Q8HZJ6	AGRN B3GALT6 B3GAT1 B3GAT2 B3GAT3 B4GALT7 BCAN BGN CSPG4 CSPG5 DCN GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 NCAN SDC1 SDC2 SDC3 SDC4 VCAN XYLT1 XYLT2	Sus scrofa (pig)
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2	Q10982 Q29043	FUT1 FUT2	Sus scrofa (pig)
APAP ADME	ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily C member 5 Aminoacylase-1 Broad substrate specificity ATP-binding cassette transporter ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cystic fibrosis transmembrane conductance regulator Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Gamma-glutamyltransferase 6 Glutathione hydrolase Glutathione hydrolase Multidrug resistance-associated protein 1 Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase arylamine N-acetyltransferase arylamine N-acetyltransferase glucuronosyltransferase glucuronosyltransferase glutathione transferase glutathione transferase	A0A286ZRB6 A0A286ZW98 A0A287A3B9 A0A287ABK7 A0A287AY60 A0A287BBR6 A0A480QK70 A0A480RQR3 A0A5G2QMB0 A0A5G2R0Q5 A0A5G2R2F8 A0A5G2R606 A0A5K1UGB8 A0A5S6GWJ4 A0A8W4F6U6 A0A8W4FC10 A0A8W4FI10 A0A8X9AEU1 F1RL37 F1S4Y1 F1S8V9 F1SNL7 I3LC84 I3LLX8 P37111 Q3S3F7 Q8MIB3	ABCC1 ABCC2 ABCC3 ABCC4 ABCC5 ABCG2 ABCG2A ACY1 BMDP CNDP2 CYP2E1 GGT1 GGT6 GGT7 GSTT1 LOC100153094 LOC100511540 LOC100515741 LOC100516628 LOC100623255 LOC100623504 LOC100739163 LOC110262115 SULT1A3 SULT1C4 SULT1E1 SULT2A1 UGT2B31	Sus scrofa (pig)
Abacavir transmembrane transport	Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	A0A287A9U9 F1SB80 O02713	OCT2 SLC22A1 SLC22A2 SLC22A3	Sus scrofa (pig)
Activated NTRK2 signals through FRS2 and FRS3	Brain-derived neurotrophic factor Growth factor receptor bound protein 2 Neurotrophin-4 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A286ZUQ0 B6E241 F1RIN3 P14082	BDNF GRB2 NTF4 SOS1	Sus scrofa (pig)
Activated NTRK2 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Brain-derived neurotrophic factor Neurotrophin-4	F1RIN3 F1SDV6 P14082	BDNF NTF4 PLCG1	Sus scrofa (pig)
Activation of Matrix Metalloproteinases	Cathepsin K Collagen type XVIII alpha 1 chain Collagenase 3 Interstitial collagenase Kallikrein 1 Matrix metallopeptidase 11 Matrix metallopeptidase 15 Matrix metallopeptidase 16 Matrix metallopeptidase 17 Matrix metallopeptidase 24 Matrix metallopeptidase 25 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-9 Metalloproteinase inhibitor 1 Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Plasminogen Procathepsin L SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 Stromelysin-1 TIMP metallopeptidase inhibitor 2 furin trypsin	A0A286ZIL9 A0A287AKC1 A0A287AQ38 A0A287AZD5 A0A287BDI2 A0A287BI78 A0A5G2QR70 A0A5G2QXR3 A0A8W4FKF9 C6L245 F1RFS7 F1RIW2 F1RMJ1 F1RWV2 F1SV56 F1SV58 F1SV69 F1SV71 I3L740 I3LDA9 I3LFQ7 P21692 Q28944 Q9GLE3	COL18A1 CTSK CTSL CTSL1 FURIN KLK1 LOC100154047 MMP1 MMP11 MMP13 MMP15 MMP16 MMP17 MMP24 MMP25 MMP3 MMP7 MMP8 MMP9 PLG PRSS2 SPOCK3 TIMP1 TIMP2 try	Sus scrofa (pig)
Activation of PKB	3-phosphoinositide-dependent protein kinase 1 Tribbles pseudokinase 3 non-specific serine/threonine protein kinase	A0A286ZV67 A0A287AQP0 A0A287BPF0	AKT2 PDPK1 TRIB3	Sus scrofa (pig)
Activation of the phototransduction cascade	Cyclic nucleotide gated channel subunit beta 1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Phosphodiesterase Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin cGMP-gated cation channel alpha-1	A0A287AW90 A0A5G2R841 A0A8W4FII8 F1RF40 F1RL89 O18766	CNGA1 CNGB1 GNB1 PDE6A PDE6G RHO RHO1	Sus scrofa (pig)
Adherens junctions interactions	Afadin, adherens junction formation factor Angiogenin Cadherin 10 Cadherin 11 Cadherin 12 Cadherin 15 Cadherin 18 Cadherin 24 Cadherin 3 Cadherin 7 Cadherin 9 Cadherin-17 Cadherin-1 Cadherin-2 Cadherin-4 Cadherin-5 Cadherin-6 Catenin alpha 1 Catenin beta-1 Catenin delta 1 Cell adhesion molecule 1 Cell adhesion molecule 2 Cell adhesion molecule 3 Junction plakoglobin Junction plakoglobin Nectin cell adhesion molecule 1 Nectin cell adhesion molecule 2 Nectin cell adhesion molecule 3 Nectin cell adhesion molecule 4	A0A286ZM64 A0A286ZQM3 A0A286ZU93 A0A287AKU3 A0A287ARL6 A0A287BKZ4 A0A2C9F3E9 A0A5G2QAH4 A0A5G2QEA9 A0A5G2QJC4 A0A5G2QPJ4 A0A5G2R8P3 A0A8W4F8U2 F1RFU7 F1RGJ2 F1S9C8 F1SAM3 F1SMX9 F1SRL4 F1SRL7 F6QAP1 I3L5Z1 I3L766 I3LCR6 I3LFD4 K7GMN4 Q1HDU1 Q8WNW3 Q8WNW5	AFDN ANG ANG1 CADM1 CADM2 CADM3 CDH1 CDH10 CDH11 CDH12 CDH15 CDH17 CDH18 CDH2 CDH24 CDH3 CDH4 CDH5 CDH6 CDH7 CDH9 CTNNA1 CTNNB1 CTNND1 JUP Jup NECTIN1 NECTIN2 NECTIN3 NECTIN4	Sus scrofa (pig)
Adrenaline signalling through Alpha-2 adrenergic receptor	Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor	I3LFJ1 P18871 Q38PT0	A2AR ADRA2A ADRA2B ADRA2C	Sus scrofa (pig)
Adrenaline,noradrenaline inhibits insulin secretion	Adenylate cyclase type 5 Adenylate cyclase type 6 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor G protein subunit beta 2 G protein subunit beta 3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma	A0A286ZLJ8 A0A286ZVN4 A0A287ADM2 A0A287AHC5 A0A287AW90 A0A287B6W0 A0A480UI36 A0A5G2QFC3 A0A5G2QYS1 A0A5G2R753 A0A8W4FGM1 B9TRW9 F1SLU8 F1SPN5 F2Z4Z8 I3L9P4 I3LFJ1 I3LM81 P18871 Q06AS6	A2AR ADCY5 ADCY6 ADRA2A ADRA2C GNAI1 GNAI2 GNB1 GNB2 GNB3 GNB5 GNG10 GNG11 GNG12 GNG3 GNG4 GNG5 GNG7 GNG8 LOC100621431 LOC110255211	Sus scrofa (pig)
Adrenoceptors	Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor Beta-3 adrenergic receptor	A0A2C9F3F6 A7BJW1 F1RR36 F1S5H5 F1S8D0 I3LFJ1 P18871 Q38PT0 Q95252 Q9TSW7 Q9TTM9	A2AR ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 BAR3 alpha-1A	Sus scrofa (pig)
Advanced glycosylation endproduct receptor signaling	Advanced glycosylation end-product specific receptor Amyloid-beta A4 protein Amyloid-beta precursor protein F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha Protein S100-A12 Protein S100-B S100 calcium binding protein A12	A0A286ZTE6 A0A5S6H0X2 A0A8W4FCZ9 A0A8W4FET6 A0A8W4FH92 P79307 P80310 Q29221	A4 AD1 AGER APP CAPZA1 CAPZA2 S100A12 S100B	Sus scrofa (pig)
Aflatoxin activation and detoxification	Aflatoxin B1 aldehyde reductase member 4 Aminoacylase-1 Cytochrome P450 1A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 Dipeptidase 1 Dipeptidase 3 Dipeptidase Dipeptidase Gamma-glutamyltransferase 6 Glutathione hydrolase Glutathione hydrolase Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 Microsomal glutathione S-transferase 3	A0A0K1TQQ0 A0A287B7I8 A0A5G2R0Q5 A0A5K1UGB8 F1S4Y1 F1SJ26 F1SUP1 I3L719 I3LA57 I3LBY7 I3LEX8 I3LFR7 P22412 P37111 P79382 Q2EN77 Q8SQ68	ACY1 AKR7A2 CYP1A2 CYP2A19 CYP3A22 CYP3A227 CYP3A29 DPEP1 DPEP2 DPEP3 GGT1 GGT6 GGT7 GST12 MGST1 MGST2 MGST3 RDP	Sus scrofa (pig)
Amine ligand-binding receptors	G-protein coupled receptor 143 G-protein coupled receptor 143	A0A286ZZS9 F1SG22	GPR143	Sus scrofa (pig)
Androgen biosynthesis	17beta-estradiol 17-dehydrogenase 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3-oxo-5-alpha-steroid 4-dehydrogenase Glycoprotein hormones alpha chain Lutropin subunit beta Polyprenol reductase Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Very-long-chain 3-oxoacyl-CoA reductase	F1S0R8 F1S4L6 I3L709 I3LJY8 I3LKG8 O18765 P01219 P01232 P19100 Q9N119	3b-HSD CGA CYP17 CYP17A1 HSD17B12 HSD17B3 HSD3B LHB LOC100525350 POMC SRD5A1 SRD5A2 ST5AR2	Sus scrofa (pig)
Antagonism of Activin by Follistatin	Follistatin Follistatin Inhibin beta A chain Inhibin beta B chain	A0A287BPF5 F1SLQ4 P03970 P10669	FST INHBA INHBB	Sus scrofa (pig)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	78 kDa glucose-regulated protein ABC-type antigen peptide transporter ABC-type antigen peptide transporter Aminopeptidase Aminopeptidase Beta-2-microglobulin Calnexin Calreticulin Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin C1-set domain-containing protein MHC class I antigen 2 MHC class I antigen 3 MHC class I antigen 6 MHC class I antigen 7 MHC class I antigen 8 Protein SEC13 homolog Protein disulfide-isomerase Protein transport protein SEC23 Protein transport protein Sec24B isoform a Protein transport protein Sec31A SEC24 homolog A, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Small COPII coat GTPase SAR1B	A0A287AFM5 A0A287AJS8 A0A287AWH7 A0A287AXF5 A0A287B0R8 A0A287BIL8 A0A5G2QUP2 A0A5G2R517 A0A8W4F753 A0A8W4FIU8 A0A8W4FKP8 A0A8W4FNN4 A5D9J3 F1RQ21 F1RTG6 F1S129 F1S155 F1SHL3 F1SU53 F6QA08 I3L8L2 K7GLU6 P28491 Q07717 Q5PYH3	B2M CALR CANX ERAP1 ERAP2 HSPA5 LOC100513601 PDIA3 SAR1B SEC13 SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A SLA-2 SLA-3 SLA-6 SLA-7 SLA-8 TAP1 TAP2	Sus scrofa (pig)
Antimicrobial peptides	Antibacterial peptide BPI fold containing family A member 2 BPI fold containing family B member 1 BPI fold containing family B member 2 BPI fold containing family B member 4 BPI fold-containing family A member 1 Bactericidal permeability-increasing protein C-type lectin domain-containing protein C-type lectin domain-containing protein Chromogranin-A Clusterin Clusterin Elafin Epididymal peptidase inhibitor Fibrinogen C-terminal domain-containing protein Granulysin Lactotransferrin Liver-expressed antimicrobial peptide 2 Lysozyme C-3 N-acetylmuramoyl-L-alanine amidase Non-secretory ribonuclease Peptidase S1 domain-containing protein Peptidoglycan recognition protein 3 Peptidoglycan recognition protein 4 Peptidoglycan-recognition protein Regenerating islet-derived 3 gamma Uncharacterized protein trypsin	A0A286ZI97 A0A287AE25 A0A287AN19 A0A287BDI2 A0A287BGS7 A0A287BLV6 A0A287BME6 A0A287BQB3 A0A5G2QHA2 A0A5G2QU73 A0A5G2R6C7 A0A5G2RCV2 A0A5G2RIT7 A0A5K1UBC7 A0A5S8KLN1 A0A8X9AES5 A7J149 B8YGC1 C6L245 F1SD66 F1SFU8 F1SNX2 K7GS01 K7GSX9 P12069 Q29125 Q29549 Q6YT39	BPI BPIFA1 BPIFA2 BPIFB1 BPIFB2 BPIFB4 CHGA CLU EPPIN GNLY LEAP2 LOC100154047 LOC100520832 LOC100624628 LOC102163838 LOC110255221 LOC110260309 LTF PGLYRP1 PGLYRP2 PGLYRP3 PGLYRP4 PMAP-36 PRSS2 REG3G try	Sus scrofa (pig)	G49108TO
Apoptotic cleavage of cell adhesion proteins	Cadherin-1 Catenin beta-1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein-1 Desmoplakin Occludin Plakophilin 1 Tight junction protein 1 Tight junction protein 2	A0A287AL69 A0A287AQX9 A0A287ATF2 A0A287BF71 F1RW75 F6QAP1 I3L5Z1 I3LA65 I3LGN8 I3LU54 Q3BDI7	CDH1 CTNNB1 DSG1 DSG2 DSG3 DSP OCLN PKP1 TJP1 TJP2	Sus scrofa (pig)
Apoptotic cleavage of cellular proteins	APC regulator of WNT signaling pathway Apoptotic chromatin condensation inducer 1 B-cell receptor-associated protein Baculoviral IAP repeat containing 2 Caspase 7 Caspase-6 Caspase-8 Claspin DNA-binding protein SATB Rho-associated protein kinase Tyrosine-protein kinase non-specific serine/threonine protein kinase protein kinase C	A0A286ZLZ9 A0A287AGZ2 A0A287B0C4 A0A287B1C5 A0A287BBY6 A0A5G2QIS7 A0A5G2QXI3 A0A5G2R3D2 F1RS63 F1S2A8 I3LH37 K7GKP6 Q56VC3	ACIN1 APC BCAP31 BIRC2 BMX CASP6 CASP7 CASP8 CLSPN PRKCD ROCK1 SATB1 STK24	Sus scrofa (pig)
Apoptotic execution phase	B-cell receptor-associated protein Caspase-8 Dynamin-1-like protein non-specific serine/threonine protein kinase	A0A287B0C4 A0A287BMW9 F1S2A8 Q56VC3	BCAP31 CASP8 DNM1L STK24	Sus scrofa (pig)
Arachidonic acid metabolism	Fatty-acid amide hydrolase 1 fatty acid amide hydrolase	A0A287B2N9 Q9TUI8	FAAH FAAH1	Sus scrofa (pig)
Asparagine N-linked glycosylation	Asialoglycoprotein receptor 1 Asialoglycoprotein receptor 2 Glycosyltransferase 2-like domain-containing protein Uromodulin	A0A5G2Q826 A0A5G2QNB6 F1RPA9 I3L7N4	ASGR1 ASGR2 LOC110255214 UMOD	Sus scrofa (pig)

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