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MIRAGE
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
BCL2 gene, BCL2L1 geneBcl-2/Bcl-X(L)BCL2Bcl2:BH3-only protein complexBcl-2 interacting BH-3 only proteinsBCL2 antagonistsBCL2:BCL2 antagoniststBID:BCL-2tBIDBcl-XL interacting BH3-only proteinsBcl-XL:BH3-only protein complexBCL2L1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 2 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P40763 Signal transducer and activator of transcription 3
  • APRF
  • STAT3
 view
Q96LC9 Bcl-2-modifying factor
  • BMF
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025