Pre-NOTCH Transcription and Translation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
CCND1:CREBBPCCND1:CREBBP:NOTCH1 GeneNOTCH1 geneE2F1/3:DP1/2:NOTCH1 GeneE2F1/3:DP1/2NOTCH1 mRNANOTCH2 geneNOTCH2 mRNANOTCH3 geneNOTCH1 coactivator complex:NOTCH3 geneNOTCH1 Coactivator ComplexELF3p-S68-ELF3ATPADPp-S68-ELF3:NOTCH3 geneNOTCH3 mRNANOTCH4 geneNOTCH4 mRNAMIR34 genesTP53 Tetramer:MIR34 genesTP53 TetramermiR-34 RISCNOTCH1 mRNA:miR-34 RISCNOTCH1 mRNA:miR-200B/C RISCmiR-200B/C RISCmiR-449 RISCNOTCH1 mRNA:miR-449 RISCNOTCH2 mRNA:miR-34 RISCNOTCH3 mRNA:miR-150 RISCmiR-150 RISCNOTCH3 mRNA:miR-206 RISCmiR-206 RISCNOTCH4 mRNA:miR-181C RISCmiR-181C RISCmiR-302A RISCNOTCH4 mRNA:miR-302A RISCNOTCH1NOTCH2NOTCH3NOTCH4RUNX1:NOTCH4 geneAML1SIRT6SIRT6:Nucleosome(H3K9ac):NOTCH1,NOTCH4 geneNOTCH1 gene,NOTCH4 geneNucleosome (H3K9ac)SIRT6:Nucleosome:NOTCH1,NOTCH4 geneNAD2'-O-acetyl-ADP-riboseNOTCH1 mRNA,NOTCH4 mRNA
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 44 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O60814 Histone H2B type 1-K
  • H2BC12
  • H2BFT
  • HIRIP1
  • HIST1H2BK
view
P04637 Cellular tumor antigen p53
  • P53
  • TP53
view
P04908 Histone H2A type 1-B/E
  • H2AC4
  • H2AC8
  • H2AFA
  • H2AFM
  • HIST1H2AB
  • HIST1H2AE
view
P05412 Transcription factor Jun
  • JUN
view
P06899 Histone H2B type 1-J
  • H2BC11
  • H2BFR
  • HIST1H2BJ
view
P16104 Histone H2AX
  • H2AFX
  • H2AX
view
P23527 Histone H2B type 1-O
  • H2BC17
  • H2BFH
  • H2BFN
  • HIST1H2BO
view
P33778 Histone H2B type 1-B
  • H2BC3
  • H2BFF
  • HIST1H2BB
view
P46531 Neurogenic locus notch homolog protein 1
  • NOTCH1
  • TAN1
view
P57053 Histone H2B type F-S
  • H2BC12L
  • H2BFS
  • H2BS1
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025