Signaling by Leptin

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
STAT32x(p-Y705-STAT3)2x(p-Y705-STAT3)LEPLEP:LEPR:JAK2LEPR:JAK2ATPLEP:LEPR:p-JAK2ADPLEP:p-LEPR:p-JAK2SHP2LEP:p-LEPR:p-JAK2:SHP2LEP:p-LEPR:p-JAK2:p-SHP2STAT5LEP:p-LEPR:p-JAK2:STAT5LEP:p-LEPR:p-JAK2:p-STAT5p-STAT5p-STAT5 dimerp-STAT5 dimerSTAT3LEP:p-LEPR:p-JAK2:STAT3LEP:p-LEPR:p-JAK2:p-STAT3SH2B1-2LEP:p-LEPR:p-JAK2:SH2B1LEP:p-LEPR:p-JAK2:SH2B1:IRS1,2IRS1,2LEP:p-LEPR:p-JAK2:SH2B1:p-IRS1,2SOCS3LEP:p-LEPR:p-JAK2:SOCS3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025