TP53 Regulates Transcription of Genes Involved in Cytochrome C Release

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
(p-S15,S20-TP53,TP63,TP73):(ASPP1,ASPP2)(p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2):BAX GeneBAX geneBAXp-S15,S20-TP53 Tetramerp-S15,S20-TP53 Tetramer:BID GeneBID GeneBIDp-S15,S20-TP53 Tetramer:CREBBP:BNIP3L GeneBNIP3L GeneKAT3ANIXTP53AIP1 Genep-S15,S20,S46-TP53 Tetramer:TP53AIP1 Genep-S15,S20,S46-TP53 Tetramerp53AIP1ZNF420:TP53AIP1 GeneApakp-S68=ApakATPADPTSAP6 Genep-S15,S20-TP53 Tetramer:TSAP6 GeneSTEAP3TSAP6:NIXTRIAP1 Genep-S15,S20-TP53 Tetramer:TRIAP1 GeneTRIAP1PRELID1, PRELID3ATRIAP1:PRELID1, PRELID3APAPAp53 Tetramer:AMID GeneAMID GeneAMIDp-S15,S20-TP53 Tetramer:TP53INP1 GeneTP53INP1 GeneTP53INP1NOXA Genep-S15,S20-TP53 Tetramer:PMAIP1 GenePMAIP1BBC3 gene(p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2):BBC3 GeneBBC3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 7 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P04637 Cellular tumor antigen p53
  • P53
  • TP53
view
Q07812 Apoptosis regulator BAX
  • BAX
  • BCL2L4
view
Q13315 Serine-protein kinase ATM
  • ATM
view
Q13625 Apoptosis-stimulating of p53 protein 2
  • ASPP2
  • BBP
  • TP53BP2
view
Q658P3 Metalloreductase STEAP3
  • STEAP3
  • TSAP6
view
Q92793 CREB-binding protein
  • CBP
  • CREBBP
view
Q9BRQ8 Ferroptosis suppressor protein 1
  • AIFM2
  • AMID
  • PRG3
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025