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MIRAGE
LXRs regulate gene expression linked to lipogenesis

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
LXR ligandNRIP1:LXR:RXR:LXR ligand:FASN geneLXR:RXRNRIP1FASN geneFASNNRIP1:LXR:RXR:LXR ligand:SCD geneSCD geneSCDSREBF1 geneNRIP1:NR1H2,3:RXR:NR1H2,3 ligand:SREBF1 geneSREBF1CLXR:RXR:LXR ligand:ANGPTL3 geneANGPTL3 geneANGPTL3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P48552 Nuclear receptor-interacting protein 1
  • NRIP1
 view
P49327 Fatty acid synthase
  • FAS
  • FASN
 view
Q13133 Oxysterols receptor LXR-alpha
  • LXRA
  • NR1H3
 view
Q9Y5C1 Angiopoietin-related protein 3
  • ANGPT5
  • ANGPTL3
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025