RHO GTPases Activate Formins

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Daam1ppDVL:DAAM1pp-DVLppDVL:DAAM1:RHOA:GTPRHOA:GTP:Mg2+G-actinProfilin:G-actinPFNRAC1:GTP:FMNL1:Profilin:G-actinSRGAP2:RAC1:GTP:FMNL1:Profilin:G-actinSrgap2H2ORAC1:GDPFMNL1PiFMNL2CDC42:GTP:FMNL2Cdc42:GTPCDC42:FMNL2:Profilin:G-actinRHOC:GTPRHOC:GTP:FMNL2FMNL3RHOC:GTP:FMNL3RHOC:GTP:FMNL3:G-actinMKL1Profilin:G-actin:MKL1RhoA:GTPRHOA:GTP:DIAPH1DIAPH1EVLRHOA:GTP:DIAPH1:EVL:Profilin:G-actinMKL1SRF:MKL1SrfScaiSRF:MKL1:SCAIDIAPH1,DIAPH3RHOB:GTP:DIAPH1,DIAPH3RHOB:GTPRHOD:GTPRHOD:GTP:DIAPH2-3DIAPH2-3SRC-2RHOD:GTP:DIAPH2:SRC-1CDC42:GTPKinetochore:CDC42:GTP:DIAPH2-2KinetochoreDIAPH2-2ATPADPKinetochore:CDC42:GTP:p-S196-DIAPH2-2Microtubule-bound kinetochoreMicrotubule
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025