10930406

Summary
Title
Identification of a novel inhibitor specific to the fungal chitin synthase. Inhibition of chitin synthase 1 arrests the cell growth, but inhibition of chitin synthase 1 and 2 is lethal in the pathogenic fungus Candida albicans.
Authors
  • Sudoh M
  • Yamazaki T
  • Masubuchi K
  • Taniguchi M
  • Shimma N
  • Arisawa M
  • Yamada-Okabe H
Source
J Biol Chem
Publication Date
2000 Oct 20
PubMed ID
10930406

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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