17666401

Summary
Title
Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the mechanism of chemical chaperone action in Gaucher disease.
Authors
  • Brumshtein B
  • Greenblatt HM
  • Butters TD
  • Shaaltiel Y
  • Aviezer D
  • Silman I
  • Futerman AH
  • Sussman JL
Source
J Biol Chem
Publication Date
2007 Sep 28
PubMed ID
17666401

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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