23060442

Summary
Title
Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear factor of activated T cell 1 (NFAT1) activation.
Authors
  • Goyal A
  • Poluzzi C
  • Willis CD
  • Smythies J
  • Shellard A
  • Neill T
  • Iozzo RV
Source
J Biol Chem
Publication Date
2012 Dec 21
PubMed ID
23060442

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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