Cooperation of binding sites at the hydrophilic domain of cell-surface sulfatase Sulf1 allows for dynamic interaction of the enzyme with its substrate heparan sulfate.

Summary
Title
Cooperation of binding sites at the hydrophilic domain of cell-surface sulfatase Sulf1 allows for dynamic interaction of the enzyme with its substrate heparan sulfate.
Authors
  • Milz F
  • Harder A
  • Neuhaus P
  • Breitkreuz-Korff O
  • Walhorn V
  • Lübke T
  • Anselmetti D
  • Dierks T
Source
Biochim Biophys Acta
Publication Date
2013 Nov
PubMed ID
23891937

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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