25288788

Summary
Title
High glucose forces a positive feedback loop connecting Akt kinase and FoxO1 transcription factor to activate mTORC1 kinase for mesangial cell hypertrophy and matrix protein expression.
Authors
  • Das F
  • Ghosh-Choudhury N
  • Dey N
  • Bera A
  • Mariappan MM
  • Kasinath BS
  • Ghosh Choudhury G
Source
J Biol Chem
Publication Date
2014 Nov 21
PubMed ID
25288788

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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