9038146

Summary
Title
Catalysis by a new sialidase, deaminoneuraminic acid residue-cleaving enzyme (KDNase Sm), initially forms a less stable alpha-anomer of 3-deoxy-D-glycero-D-galacto-nonulosonic acid and is strongly inhibited by the transition state analogue, 2-deoxy-2, 3-didehydro-D-glycero-D-galacto-2-nonulopyranosonic acid, but not by 2-deoxy-2,3-didehydro-N-acetylneuraminic acid.
Authors
  • Terada T
  • Kitajima K
  • Inoue S
  • Wilson JC
  • Norton AK
  • Kong DC
  • Thomson RJ
  • von Itzstein M
  • Inoue Y
Source
J Biol Chem
Publication Date
1997 Feb 28
PubMed ID
9038146

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