luminal breast carcinoma A

Summary
Synonym
  • Luminal A Breast Carcinoma
Definition
A breast carcinoma that is characterized by high expression of genes characteristic of luminal epithelial cells, including estrogen receptor (ER), estrogen regulated protein LIV-1, and the transcription factors hepatocyte nuclear factor 3, HNF3A, XBP1, and GATA 3.
Super Class
breast carcinoma
External Links
Disease Ontology
DOID:0060548
UMLS
NCI Thesaurus
Related Genes
Displaying entries 11 - 17 of 17 in total
Gene ID Gene Symbol Description Source
5728 PTEN phosphatase and tensin homolog
8809 IL18R1 interleukin 18 receptor 1
9420 CYP7B1 cytochrome P450 family 7 subfamily B member 1
9563 H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
23583 SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
25796 PGLS 6-phosphogluconolactonase
26035 GLCE glucuronic acid epimerase

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024