age related macular degeneration

Summary
Synonym
  • Age Related Maculopathies
  • Age Related Maculopathy
  • Senile macular degeneration
  • Senile macular retinal degeneration
  • age-related macular degeneration
Definition
A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision.
Super Class
autosomal dominant disease degeneration of macula and posterior pole
External Links
Disease Ontology
DOID:10871
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 68 in total
Gene ID Gene Symbol Description Source
38 ACAT1 acetyl-CoA acetyltransferase 1
48 ACO1 aconitase 1
142 PARP1 poly(ADP-ribose) polymerase 1
224 ALDH3A2 aldehyde dehydrogenase 3 family member A2
811 CALR calreticulin
847 CAT catalase
1116 CHI3L1 chitinase 3 like 1
1544 CYP1A2 cytochrome P450 family 1 subfamily A member 2
1557 CYP2C19 cytochrome P450 family 2 subfamily C member 19
1589 CYP21A2 cytochrome P450 family 21 subfamily A member 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
19017 Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Displaying 1 entry
Gene ID Gene Symbol Description Source
83516 Ppargc1a PPARG coactivator 1 alpha

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024