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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-C motif chemokine ligand 2
Summary
- Gene Symbol
-
- Ccl2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Chemotaxis
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Pyrrolidone carboxylic acid
- Reference proteome
- Secreted
- Signal
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to wounding | ||
| positive regulation of cellular extravasation | ||
| positive regulation of collagen biosynthetic process | ||
| positive regulation of synaptic transmission, glutamatergic | ||
| positive regulation of protein targeting to membrane |
GO Hierarchy
- response to activity
biological process
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
cellular response to chemical stimulus [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
positive regulation of cellular process [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| axon terminus | ||
| endocytic vesicle | ||
| perikaryon | ||
| neuronal cell body | ||
| C-fiber |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| heparin binding | ||
| G protein-coupled receptor binding | ||
| chemokine activity | ||
| CCR chemokine receptor binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- C-C motif chemokine 2
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| cell chemotaxis |
| chemokine activity |
| chemotaxis |
| cytokine activity |
| eosinophil chemotaxis |
| immune response |
| InterPro |
|---|
| CC chemokine, conserved site |
| Chemokine beta/gamma/delta |
| Chemokine interleukin-8-like domain |
| Chemokine interleukin-8-like superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050700 | cardiomyopathy | |
| DOID:0050848 | obstructive sleep apnea | |
| DOID:0050866 | oral squamous cell carcinoma | |
| DOID:0060180 | colitis | |
| DOID:0080162 | lupus nephritis | |
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0080547 | metabolic dysfunction-associated steatohepatitis | |
| DOID:0080600 | COVID-19 | |
| DOID:0080998 | acute necrotizing pancreatitis | |
| DOID:0081120 | Graves ophthalmopathy |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 6347 | HGNC:10618 | |||
| 6357 | HGNC:10611 | |||
| 24770 | 10116_1:0037ad | RGD:3645 | RATNO02716 | |
| 100034523 | ZFIN:ZDB-GENE-041014-165 | |||
| 100135493 | CAVPO14046 | |||
| 100135494 | CAVPO14133 | |||
| 100379541 | CAVPO14047 | |||
| 100536999 | ZFIN:ZDB-GENE-110411-218 | |||
| 100763833 | 10029_0:0042c5 | CRIGR01154 | ||
| 100764122 | CRIGR01157 |
