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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sickle cell anemia
Summary
- Synonym
-
- Hb SC disease
- Hb-S/Hb-C disease
- Hb-SS disease without crisis
- Hemoglobin S disease without crisis
- Sickle-cell/Hb-C disease without crisis
- drepanocytosis
- haemoglobin SC disease
- hemoglobin SC disease
- sickle cell anaemia
- Definition
- A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
- Super Class
- autosomal recessive disease blood protein disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1636 | ACE | angiotensin I converting enzyme | |
| 1727 | CYB5R3 | cytochrome b5 reductase 3 | |
| 2215 | FCGR3B | Fc gamma receptor IIIb | |
| 2224 | FDPS | farnesyl diphosphate synthase | |
| 2271 | FH | fumarate hydratase | |
| 2519 | FUCA2 | alpha-L-fucosidase 2 | |
| 2523 | FUT1 | fucosyltransferase 1 (H blood group) | |
| 2539 | G6PD | glucose-6-phosphate dehydrogenase | |
| 2571 | GAD1 | glutamate decarboxylase 1 | |
| 2597 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9BTY2 | Plasma alpha-L-fucosidase | |
| Q9HAW7 | UDP-glucuronosyltransferase 1A7 | |
| Q9HAW8 | UDP-glucuronosyltransferase 1A10 | |
| Q9HAW9 | UDP-glucuronosyltransferase 1A8 | |
| Q9NRA2 | Sialin | |
| Q9NYU2 | UDP-glucose:glycoprotein glucosyltransferase 1 | |
| Q9UEF7 | Klotho | |
| Q9Y5X9 | Endothelial lipase |
